LOCUS HSU75645 2590 bp mRNA linear HUM 16-NOV-2000
DEFINITION Human PEX protein mRNA, complete cds.
ACCESSION U75645
VERSION U75645.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2590)
AUTHORS Beck,L., Soumounou,Y., Martel,J., Krishnamurthy,G., Gauthier,C.,
Goodyer,C.G. and Tenenhouse,H.S.
TITLE Pex/PEX tissue distribution and evidence for a deletion in the 3'
region of the Pex gene in X-linked hypophosphatemic mice
JOURNAL J. Clin. Invest. 99 (6), 1200-1209 (1997)
PUBMED 9077527
REFERENCE 2 (bases 1 to 2590)
AUTHORS Beck,L. and Soumounou,Y.
TITLE Direct Submission
JOURNAL Submitted (21-OCT-1996) Biochemical Genetics, Montreal Children's
Hospital, 2300 Tupper, Montreal, Qc H3H 1P3, Canada
FEATURES Location/Qualifiers
source 1..2590
/db_xref="H-InvDB:HIT000221265"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xp22.1-22.2"
gene 1..2590
/gene="PEX"
CDS 77..2326
/gene="PEX"
/note="similar to metalloendopeptidase; X-linked
hypophosphatemia candidate gene"
/codon_start=1
/product="PEX protein"
/protein_id="AAB47749.1"
/translation="MEAETGSSVETGKKANRGTRIALVVFVGGTLVLGTILFLVSQGL
LSLQAKQEYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYG
VYPWLRHNVDLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHIL
RHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEH
ILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLR
LEIKIAEIMIPHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDIS
PSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRV
IQGTTTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDML
EKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQ
TRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYP
RSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSN
YYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLPGITFTNNQ
LFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMN
RGMDSCRLW"
BASE COUNT 769 a 544 c 615 g 662 t
ORIGIN
1 aacgcctcgc tcttgagacc agccaccaaa ccacgaaaag tgactttctt ctcgtgtgct
61 ctctacggcc cttctgatgg aagcagaaac agggagcagc gtggagactg gaaagaaggc
121 caacagaggc actcgaattg ccctggtcgt gtttgtcggt ggcaccctag ttctgggcac
181 gatcctcttt ctagtgagtc aaggtctctt aagtctccaa gctaaacagg agtactgcct
241 gaagccagaa tgcatcgaag cggctgctgc catcttaagt aaagtaaatc tgtctgtgga
301 tccttgtgat aatttcttcc ggttcgcttg tgatggctgg ataagcaata atccaattcc
361 cgaagatatg ccaagctatg gggtttatcc ttggctgaga cataatgttg acctcaagtt
421 gaaggaactt ttggagaaat caatcagtag aaggcgggac accgaagcca tacagaaagc
481 caaaatcctt tattcatcct gcatgaatga gaaagcgatt gaaaaagcag atgccaagcc
541 actgctacac atcctacggc attcaccttt ccgctggccc gtgcttgaat ctaatattgg
601 ccctgaaggg gtttggtcag agagaaagtt cagccttctg cagacacttg caacgtttcg
661 tggtcaatac agcaattctg tgttcatccg tttgtatgtg tcccctgatg acaaagcatc
721 caatgaacat atcttgaagc tggaccaagc aacactctcc ctggccgtga gggaagacta
781 ccttgataac agtacagaag ccaagtctta tcgggatgcc ctttacaagt tcatggtgga
841 tactgccgtg cttttaggag ctaacagttc cagagcagag catgacatga agtcagtgct
901 cagattggaa attaagatag ctgagataat gattccacat gaaaaccgaa ccagcgaggc
961 catgtacaac aaaatgaaca tttctgaact gagtgctatg attccccagt tcgactggct
1021 gggctacatc aagaaggtca ttgacaccag actctacccc catctgaaag acatcagccc
1081 ctccgagaat gtggtggtcc gcgtcccgca gtactttaaa gatttgttta ggatattagg
1141 gtctgagaga aagaagacca ttgccaacta tttggtgtgg agaatggttt attccagaat
1201 tccaaacctt agcaggcgct ttcagtatag atggctggaa ttctcaaggg taatccaggg
1261 gaccacaact ttgctgcctc aatgggacaa atgtgtaaac tttattgaaa gtgccctccc
1321 ttatgttgtt ggaaagatgt ttgtagatgt gtacttccag gaagataaga aggaaatgat
1381 ggaggaattg gttgagggcg ttcgctgggc ctttattgac atgctagaga aagaaaatga
1441 gtggatggat gcaggaacga aaaggaaagc caaagaaaag gcgagagctg ttttggcaaa
1501 agttggctat ccagagttta taatgaatga tactcatgtt aatgaagacc tcaaagctat
1561 caagttttca gaagccgact actttggcaa cgtcctacaa actcgcaagt atttagcaca
1621 gtctgatttc ttctggctaa gaaaagccgt tccaaaaaca gagtggttta caaatccgac
1681 gactgtcaat gccttctaca gtgcatccac caaccagatc cgatttccag caggagagct
1741 ccagaagcct ttcttttggg gaacagaata tcctcgatct ctgagttatg gtgctatagg
1801 agtaattgtc ggacatgaat ttacacatgg atttgataat aatggtagaa aatatgataa
1861 aaatggaaac ctggatcctt ggtggtctac tgaatcagaa gaaaagttta aggaaaaaac
1921 aaaatgcatg attaaccagt atagcaacta ttattggaag aaagctggct taaatgtcaa
1981 ggggaagagg accctgggag aaaatattgc tgataatgga ggcctgcggg aagcttttag
2041 ggcttacagg aaatggataa atgacagaag gcagggactt gaggagcctc ttctaccagg
2101 catcacattc accaacaacc agctcttctt cctgagttat gctcatgtga ggtgcaattc
2161 ctacagacca gaagctgccc gagaacaagt ccaaattggt gctcacagtc cccctcagtt
2221 tagggtcaat ggtgcaatta gtaactttga agaattccag aaagctttta actgtccacc
2281 caattccacg atgaacagag gcatggactc ctgccgactc tggtagctgg gacgctggtt
2341 tatggcatcc tgagacagtt gcacagtgcc agcggaggct gcactgagcc ttcatcgccc
2401 attgctttag gcctggagac tttcattttt agtgcatttt cattatttgg gtaggtgacc
2461 tgcttggatc tagacagcat ctgttcaaag tcgtagggct tataaagtgg aatataagaa
2521 tgaactaagt atgtttcttt agaaaatcaa accaacaaaa ataaatccct aggctacttt
2581 tgttaaaaaa
//