LOCUS HSU75330 4723 bp mRNA linear HUM 10-OCT-1997
DEFINITION Human neural cell adhesion protein (NCAM21) mRNA, complete cds.
ACCESSION U75330
VERSION U75330.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4723)
AUTHORS Paoloni-Giacobino,A., Chen,H. and Antonarakis,S.E.
TITLE Cloning of a novel human neural cell adhesion molecule gene (NCAM2)
that maps to chromosome region 21q21 and is potentially involved in
Down syndrome
JOURNAL Genomics 43 (1), 43-51 (1997)
PUBMED 9226371
REFERENCE 2 (bases 1 to 4723)
AUTHORS Paoloni-Giacobino,A., Chen,H. and Antonarakis,S.E.
TITLE Direct Submission
JOURNAL Submitted (17-OCT-1996) Medical Genetics, University of Geneva
Medical School, 1 Michel-Servet Street, Geneva 1211, Switzerland
FEATURES Location/Qualifiers
source 1..4723
/db_xref="H-InvDB:HIT000221255"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="21"
/map="21q21"
gene 1..4723
/gene="NCAM21"
CDS 70..2583
/gene="NCAM21"
/codon_start=1
/product="neural cell adhesion protein"
/protein_id="AAB80803.1"
/translation="MSLLLSFYLLGLLVSSGQALLQVTISLSKVELSVGESKFFTCTA
IGEPRSIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDAGIYRCQATDAKGQT
QEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISD
NRLAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSF
NATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDG
GPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITW
KRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRIGGHQKS
MYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLK
TYSTGRKMILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELS
QTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIWKIVRSHGVQTMVVLNNLEPNTTYE
IRVAAVNGKGQGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSFKLSITKQDDGGAPIL
EYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGMKFRLPAANRLGYSEPTVYEF
SMPPKPNIIKDTLFNGLGLGAVIGLGVAALLLILVVTDVSCFFIRQCGLLMCITRRMC
GKKSGSSGKSKELEEGKAAYLKDGSKEPIVEMRTEDERVTNHEDGSPVNEPNETTPLT
EPEKLPLKEEDGKEALNPETIEIKVSNDIIQSKEDDSKA"
BASE COUNT 1583 a 826 c 971 g 1343 t
ORIGIN
1 gaattccggt ctctctccag ggctggactt aataactttg aaactgtcca ccggtgtcac
61 gtcctgaaca tgagcctcct cctctccttc tacctgctgg ggttgcttgt cagtagcggg
121 caagctcttc ttcaagtgac aatttcactt agcaaagtag agcttagtgt tggagaatct
181 aaattcttca catgtacagc gattggtgaa cctagaagta ttgattggta taatcctcaa
241 ggagagaaga taatttcaac acagagggta gtagtgcaaa agggaggtgt taggtcacgg
301 ttaaccatct acaatgcaaa tatagaagat gcagggatat atcgttgtca agcaacagat
361 gccaaaggac aaacacaaga agctacagta gttttggaaa tttaccaaaa actcactttc
421 agagaagtgg tatctccaca agaattcaaa caaggagaag atgcagaagt ggtttgccga
481 gttagcagtt cacctgcacc tgctgtcagc tggttgtatc ataatgagga agtcaccact
541 atttccgaca atcggctcgc tatgttagca aacaataacc tgcagattct caacatcaat
601 aaaagtgatg aaggtatata cagatgtgaa ggaagagtgg aggccagggg agaaattgac
661 ttccgtgata tcattgttat tgttaatgtg ccgccagcaa tctctatgcc tcagaaatct
721 tttaatgcca cagcagagag aggagaagaa atgacatttt cctgcagggc ctcaggctct
781 ccagaacccg ccatctcctg gttcaggaat ggcaagctca ttgaagaaaa tgagaagtac
841 atattgaaag ggagcaatac agaactcact gtcaggaaca taatcaatag tgatggtggt
901 ccttatgtct gcagggccac aaataaggca ggagaagatg aaaagcaagc tttcctccaa
961 gtctttgtac agcctcacat aatacagctt aaaaatgaaa ctacatatga gaatggtcaa
1021 gtcacactcg tatgtgatgc ggaaggggag cctattccag aaatcacttg gaaaagagct
1081 gtggatggct tcacgttcac tgaaggcgat aagagcccgg acggccgtat cgaagtcaaa
1141 gggcagcatg gaagctcatc actgcatatt aaagatgtga agttgtcagg ctcagggaga
1201 tatgactgtg aagctgcaag cagaattgga gggcatcaaa agagcatgta ccttgatatt
1261 gaatatgccc ccaagtttat atcaaaccaa acaatttatt actcttggga aggaaatcct
1321 atcaatataa gttgtgatgt gaaatcgaat ccaccagcat caattcactg gagaagagat
1381 aaattagtct tacctgctaa aaacacgacc aatttaaaga cttatagtac aggaagaaag
1441 atgatattag agattgcacc tacatctgac aatgactttg gacgctataa ttgcacagcc
1501 actaatcata taggaacaag atttcaagaa tatattcttg ctttggctga cgtgccatcc
1561 agtccctatg gagtgaagat catagagctg tcgcagacca cggccaaggt ttccttcaac
1621 aaaccggact cccatggagg tgtacctatt catcactatc aggtggatgt caaagaagta
1681 gcgtcagaaa tctggaaaat tgtacgctcc catggagttc aaacaatggt tgttttgaac
1741 aacctggaac caaatacaac ttatgaaatt agggttgcag ctgtaaatgg aaagggacaa
1801 ggagactaca gtaaaataga aatcttccaa acattaccag ttcgtgaacc aagtcctcca
1861 tccatacatg gacagccaag cagtggaaag agctttaaac tcagcatcac caaacaggac
1921 gatggagggg cccctatttt ggaatacatt gtgaaatata gaagtaaaga taaggaagac
1981 caatggctag agaaaaaagt gcaaggaaat aaagaccaca tcattttgga gcatctccag
2041 tggaccatgg ggatgaagtt cagattacca gctgccaata gattgggata ttctgaaccg
2101 acagtttatg aattcagcat gccaccaaag cccaacatta ttaaagacac gctgtttaat
2161 ggtcttgggc ttggagcagt aattggcctg ggagttgctg cactgctgct aattcttgtg
2221 gtaacagacg tcagctgctt ctttattcgg caatgtgggt tgctgatgtg catcactagg
2281 agaatgtgtg gaaagaaaag tggctccagt ggcaaaagta aagaactcga agaaggaaaa
2341 gctgcatacc tgaaagatgg atcaaaagaa ccaatagtgg agatgagaac agaggatgaa
2401 agagttacta atcacgaaga tgggagccca gtaaatgagc caaatgaaac cacaccactg
2461 acagaacctg aaaaattgcc tttaaaggaa gaagatggga aagaagctct aaatccagaa
2521 actatagaaa ttaaagtttc taacgacatc attcaatcaa aagaagacga cagcaaagca
2581 taacaacaat attacagggg cttgaacaac actacgaaga gtatttggat tgcgtgaccc
2641 tatgaccaaa actattccat tgaccttaat ttcttgggaa acttctagct tggaatagct
2701 tgtacacata tacatatgat caaatactcc tggcccatgg atccattccc ttttgttatt
2761 gttgttgttg ttgctgttgt tgttaatttt gttaagaatt tcaatatcaa gactgactgg
2821 caccaacact ttggtattca atttgattct atgactgaag tactggaatt tattatgtgg
2881 ctaaagtgct ctatttatta agaactatat ttaataccac caacaaatat aggggttaag
2941 gaaaaaaaac gttgagctac atgtgtaaga aggccctgca tgtgtatgag tcctattctg
3001 ggcaaataga ttcttaaagt ggctttcaac ttcaagatga aggagcttaa taatggttac
3061 tcattttatc aggggaattt cagggaacgt aggcgtcaaa gagccagtta tctttagcag
3121 atattaaaaa ttgaaaactt tggagaactc atttcaagtt atgattcagt gcattttcaa
3181 cattgatttt tgatagactg aagtgccaga tcaaaattgt tacccatttg aaagaatatt
3241 agttgtatat aaaattagat tagaaagact ttcctaaatc tctatctctt tatatatgtc
3301 ctattcattc acaatggatt atacaaaaaa aagtgtattg caagtgaaat aatattgatt
3361 tctgccctca gcttcaaata aagtaaattg aaatgggaac aatatcaata tggtgtcttg
3421 atatatttat aaatatgtga ttatcattta tttttaaaat aatttatcaa aaaacaagtc
3481 tttagtgttc aaatacttca aatcatatcc tcagatatat ttttagccca tggttttata
3541 taatctttaa gaactaattt taccactgtt ataggttcac cattaaatat aattggctaa
3601 taaaaatttt aaggttgact aaattaagaa gaaattattt aacattttaa tgtgccataa
3661 aagagtaaat gataaataat taaatgccac tatgtgttct attccggatg ttctagctag
3721 aagtcatttt aagattttga taaacaactt tggttgaaga aattccttaa gtattcaaca
3781 caaactttct aatatctttt gttagggtta taccagaata aaatgcttct ttacttccaa
3841 gctatgcaag ctcccagagg taatagagtg acacatgatt taacttatat gtaaggttta
3901 aaaaagtatt tatcattata aacatacata ccatttggga gcaggtttat taaccttgag
3961 agccaaaggt ttccttaggc cctgtaacat tcagaacctt tggtgtttca ggtggtatta
4021 tagctcaaat agtgacagga cagggaatgc gttccaaagg aatattggag caattttaac
4081 attgcagaaa cctgctctgg gtgtgtctct ctgtagagat aacctgatga ttattaaatg
4141 taaaattaag gcaactcatg aatattttta tttacaaagt gcttgaaact cagccaagga
4201 gagaaaacta agtactttta tataattcat cacttttctg gctacagcag gacagaatat
4261 gaccaccttc gtttgaaggc accaaatcgt cgcagtgtct ttgccataag ttgcagggtt
4321 aaatgcggaa atctctcctt gcgttcctgt ctggcgtatt ctgaagaaaa gaacagaatt
4381 cttgtgccta cctaagaatt tgagtagtgt ctaaacaaac aaagcagtta ggtcatttta
4441 actgacttga ttatccaact ggtctttgac agatttgact gtccatattt agtttatgtt
4501 tgtctgatca tccagtttgc tttatttggc tgtgtttaat ttggtggttg gtttggtttg
4561 gtaccagtgt actaaaacta gtcaaaatac ttgaattagt ttgtttgtgc aaagtgtaca
4621 accttagtaa agtgtccatg aagcaatagc catgaatgct aattatttct aaatagggcc
4681 acatggtttt aaactaatga tggtgaaaga aatacgatga ctg
//