LOCUS HSU75329 2479 bp mRNA linear HUM 10-OCT-1997
DEFINITION Human serine protease mRNA, complete cds.
ACCESSION U75329
VERSION U75329.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2479)
AUTHORS Paoloni-Giacobino,A., Chen,H., Peitsch,M.C., Rossier,C. and
Antonarakis,S.E.
TITLE Cloning of the TMPRSS2 gene, which encodes a novel serine protease
with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3
JOURNAL Genomics 44 (3), 309-320 (1997)
PUBMED 9325052
REFERENCE 2 (bases 1 to 2479)
AUTHORS Paoloni-Giacobino,A., Chen,H. and Antonarakis,S.E.
TITLE Direct Submission
JOURNAL Submitted (17-OCT-1996) Medical Genetics, University of Geneva
Medical School, 1 Michel-Servet Street, Geneva 1211, Switzerland
FEATURES Location/Qualifiers
source 1..2479
/db_xref="H-InvDB:HIT000221254"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="21"
/map="21q22.3"
CDS 57..1535
/codon_start=1
/product="serine protease"
/protein_id="AAC51784.1"
/translation="MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQY
YPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAA
GLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQM
YSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGN
VDIYKKLYHSDACSSKAVVSLRCLACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQ
NVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVQKVISH
PNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGK
TSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSNN
NIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMKANG"
BASE COUNT 578 a 650 c 677 g 574 t
ORIGIN
1 gtcatattga acattccaga tacctatcat tactcgatgc tgttgataac agcaagatgg
61 ctttgaactc agggtcacca ccagctattg gaccttacta tgaaaaccat ggataccaac
121 cggaaaaccc ctatcccgca cagcccactg tggtccccac tgtctacgag gtgcatccgg
181 ctcagtacta cccgtccccc gtgccccagt acgccccgag ggtcctgacg caggcttcca
241 accccgtcgt ctgcacgcag cccaaatccc catccgggac agtgtgcacc tcaaagacta
301 agaaagcact gtgcatcacc ttgaccctgg ggaccttcct cgtgggagct gcgctggccg
361 ctggcctact ctggaagttc atgggcagca agtgctccaa ctctgggata gagtgcgact
421 cctcaggtac ctgcatcaac ccctctaact ggtgtgatgg cgtgtcacac tgccccggcg
481 gggaggacga gaatcggtgt gttcgcctct acggaccaaa cttcatcctt cagatgtact
541 catctcagag gaagtcctgg caccctgtgt gccaagacga ctggaacgag aactacgggc
601 gggcggcctg cagggacatg ggctataaga ataattttta ctctagccaa ggaatagtgg
661 atgacagcgg atccaccagc tttatgaaac tgaacacaag tgccggcaat gtcgatatct
721 ataaaaaact gtaccacagt gatgcctgtt cttcaaaagc agtggtttct ttacgctgtt
781 tagcctgcgg ggtcaacttg aactcaagcc gccagagcag gatcgtgggc ggtgagagcg
841 cgctcccggg ggcctggccc tggcaggtca gcctgcacgt ccagaacgtc cacgtgtgcg
901 gaggctccat catcaccccc gagtggatcg tgacagccgc ccactgcgtg gaaaaacctc
961 ttaacaatcc atggcattgg acggcatttg cggggatttt gagacaatct ttcatgttct
1021 atggagccgg ataccaagta caaaaagtga tttctcatcc aaattatgac tccaagacca
1081 agaacaatga cattgcgctg atgaagctgc agaagcctct gactttcaac gacctagtga
1141 aaccagtgtg tctgcccaac ccaggcatga tgctgcagcc agaacagctc tgctggattt
1201 ccgggtgggg ggccaccgag gagaaaggga agacctcaga agtgctgaac gctgccaagg
1261 tgcttctcat tgagacacag agatgcaaca gcagatatgt ctatgacaac ctgatcacac
1321 cagccatgat ctgtgccggc ttcctgcagg ggaacgtcga ttcttgccag ggtgacagtg
1381 gagggcctct ggtcacttcg aacaacaata tctggtggct gataggggat acaagctggg
1441 gttctggctg tgccaaagct tacagaccag gagtgtacgg gaatgtgatg gtattcacgg
1501 actggattta tcgacaaatg aaggcaaacg gctaatccac atggtcttcg tccttgacgt
1561 cgttttacaa gaaaacaatg gggctggttt tgcttccccg tgcatgattt actcttagag
1621 atgattcaga ggtcacttca tttttattaa acagtgaact tgtctggctt tggcactctc
1681 tgccatactg tgcaggctgc agtggctccc ctgcccagcc tgctctccct aaccccttgt
1741 ccgcaagggg tgatggccgg ctggttgtgg gcactggcgg tcaattgtgg aaggaagagg
1801 gttggaggct gcccccattg agatcttcct gctgagtcct ttccaggggc caattttgga
1861 tgagcatgga gctgtcactt ctcagctgct ggatgacttg agatgaaaaa ggagagacat
1921 ggaaagggag acagccaggt ggcacctgca gcggctgccc tctggggcca cttggtagtg
1981 tccccagcct acttcacaag gggattttgc tgatgggttc ttagagcctt agcagccctg
2041 gatggtggcc agaaataaag ggaccagccc ttcatgggtg gtgacgtggt agtcacttgt
2101 aaggggaaca gaaacatttt tgttcttatg gggtgagaat atagacagtg cccttggtgc
2161 gagggaagca attgaaaagg aacttgccct gagcactcct ggtgcaggtc tccacctgca
2221 cattgggtgg ggctcctggg agggagactc agccttcctc ctcatcctcc ctgaccctgc
2281 tcctagcacc ctggagagtg aatgcccctt ggtccctggc agggcgccaa gtttggcacc
2341 atgtcggcct cttcaggcct gatagtcatt ggaaattgag gtccatgggg gaaatcaagg
2401 atgctcagtt taaggtacac tgtttccatg ttatgtttct acacattgat ggtggtgacc
2461 ctgagttcaa agccatctt
//