LOCUS HSU75285 14796 bp DNA linear HUM 02-SEP-2004
DEFINITION Homo sapiens apoptosis inhibitor survivin gene, complete cds.
ACCESSION U75285
VERSION U75285.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 14796)
AUTHORS Altieri,D.C.
TITLE Molecular cloning of effector cell protease receptor-1, a novel
cell surface receptor for the protease factor Xa
JOURNAL J. Biol. Chem. 269 (5), 3139-3142 (1994)
PUBMED 8106347
REFERENCE 2 (bases 1 to 14796)
AUTHORS Altieri,D.C.
TITLE Splicing of effector cell protease receptor-1 mRNA is modulated by
an unusual retained intron
JOURNAL Biochemistry 33 (46), 13848-13855 (1994)
PUBMED 7947793
REFERENCE 3 (bases 1 to 14796)
AUTHORS Ambrosini,G., Adida,C. and Altieri,D.C.
TITLE A novel anti-apoptosis gene, survivin, expressed in cancer and
lymphoma
JOURNAL Nat. Med. 3 (8), 917-921 (1997)
PUBMED 9256286
REFERENCE 4 (bases 1 to 14796)
AUTHORS Altieri,D.C., Adida,C. and Ambrosini,G.
TITLE Direct Submission
JOURNAL Submitted (17-OCT-1996) Pathology, Boyer Center for Molecular
Medicine Rm.436B, Yale University School of Medicine, 295 Congress
Ave., New Haven, CT 06536, USA
FEATURES Location/Qualifiers
source 1..14796
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q25"
mRNA join(2762..2921,3174..3283,5158..5275,11955..13185)
/product="apoptosis inhibitor survivin"
variation 2780
/replace="c"
CDS join(2811..2921,3174..3283,5158..5275,11955..12044)
/function="IAP-related inhibitor of apoptosis
over-expressed in common human cancers, in vivo"
/note="Recombinant expression of survivin counteracts
apoptosis induced by growth factor (IL-3) withdrawal in
pre-B cell transfectants. Survivin expression is
developmentally regulated: present during fetal
development but undetectable in terminally differentiated
normal adult tissues, survivin is abundantly expressed in
transformed cell lines and in all the most common solid
cancers and in 50% of high-grade non Hodgkin's lymphoma.
The coding strand of the survivin gene product is highly
homologous and complementary to the sequence of Effector
cell Protease Receptor-1 (EPR-1) encoded by GenBank
Accession Numbers L26245 and L32866. Single-strand
specific probes identify two separate mRNA transcripts for
EPR-1 and survivin with distinct molecular sizes and
non-overlapping distribution in fetal and adult tissues"
/codon_start=1
/product="apoptosis inhibitor survivin"
/protein_id="AAC51660.1"
/translation="MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFI
HCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFL
KLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD"
polyA_site 13185
BASE COUNT 3482 a 3488 c 3888 g 3938 t
ORIGIN
1 tctagacatg cggatatatt caagctgggc acagcacagc agccccaccc caggcagctt
61 gaaatcagag ctggggtcca aagggaccac accccgaggg actgtgtggg ggtcggggca
121 cacaggccac tgcttccccc cgtctttctc agccattcct gaagtcagcc tcactctgct
181 tctcagggat ttcaaatgtg cagagactct ggcacttttg tagaagcccc ttctggtcct
241 aacttacacc tggatgctgt ggggctgcag ctgctgctcg ggctcgggag gatgctgggg
301 gcccggtgcc catgagcttt tgaagctcct ggaactcggt tttgagggtg ttcaggtcca
361 ggtggacacc tgggctgtcc ttgtccatgc atttgatgac attgtgtgca gaagtgaaaa
421 ggagttaggc cgggcatgct ggcttatgcc tgtaatccca gcactttggg aggctgaggc
481 gggtggatca cgaggtcagg agttcaatac cagcctggcc aagatggtga aaccccgtct
541 ctactaaaaa tacaaaaaaa ttagccgggc atggtggcgg gcgcatgtaa tcccagctac
601 tgggggggct gaggcagaga attgctggaa cccaggagat ggaggttgca gtgagccaag
661 attgtgccac tgcactgcac tccagcctgg cgacagagca agactctgtc tcaaaaaaaa
721 aaaaaaaaag tgaaaaggag ttgttccttt cctccctcct gagggcaggc aactgctgcg
781 gttgccagtg gaggtggtgc gtccttggtc tgtgcctggg ggccacccca gcagaggcca
841 tggtggtgcc agggcccggt tagcgagcca atcagcagga cccaggggcg acctgccaaa
901 gtcaactgga tttgataact gcagcgaagt taagtttcct gattttgatg attgtgttgt
961 ggttgtgtaa gagaatgaag tatttcgggg tagtatggta atgccttcaa cttacaaacg
1021 gttcaggtaa accacccata tacatacata tacatgcatg tgatatatac acatacaggg
1081 atgtgtgtgt gttcacatat atgaggggag agagactagg ggagagaaag taggttgggg
1141 agagggagag agaaaggaaa acaggagaca gagagagagc ggggagtaga gagagggaag
1201 gggtaagaga gggagaggag gagagaaagg gaggaagaag cagagagtga atgttaaagg
1261 aaacaggcaa aacataaaca gaaaatctgg gtgaagggta tatgagtatt ctttgtacta
1321 ttcttgcaat tatcttttat ttaaattgac atcgggccgg gcgcagtggc tcacatctgt
1381 aatcccagca ctttgggagg ccgaggcagg cagatcactt gaggtcagga gtttgagacc
1441 agcctggcaa acatggtgaa accccatctc tactaaaaat acaaaaatta gcctggtgtg
1501 gtggtgcatg cctttaatct cagctactcg ggaggctgag gcaggagaat cgcttgaacc
1561 cgtggcgggg aggaggttgc agtgagctga gatcatgcca ctgcactcca gcctgggcga
1621 tagagcgaga ctcagtttca aataaataaa taaacatcaa aataaaaagt tactgtatta
1681 aagaatgggg gcggggtggg aggggtgggg agaggttgca aaaataaata aataaataaa
1741 taaaccccaa aatgaaaaag acagtggagg caccaggcct gcgtggggct ggagggctaa
1801 taaggccagg cctcttatct ctggccatag aaccagagaa gtgagtggat gtgatgccca
1861 gctccagaag tgactccaga acaccctgtt ccaaagcaga ggacacactg attttttttt
1921 taataggctg caggacttac tgttggtggg acgccctgct ttgcgaaggg aaaggaggag
1981 tttgccctga gcacaggccc ccaccctcca ctgggctttc cccagctccc ttgtcttctt
2041 atcacggtag tggcccagtc cctggcccct gactccagaa ggtggccctc ctggaaaccc
2101 aggtcgtgca gtcaacgatg tactcgccgg gacagcgatg tctgctgcac tccatccctc
2161 ccctgttcat ttgtccttca tgcccgtctg gagtagatgc tttttgcaga ggtggcaccc
2221 tgtaaagctc tcctgtctga cttttttttt ttttttagac tgagttttgc tcttgttgcc
2281 taggctggag tgcaatggca caatctcagc tcactgcacc ctctgcctcc cgggttcaag
2341 cgattctcct gcctcagcct cccgagtagt tgggattaca ggcatgcacc accacgccca
2401 gctaattttt gtatttttag tagagacaag gtttcaccgt gatggccagg ctggtcttga
2461 actccaggac tcaagtgatg ctcctgccta ggcctctcaa agtgttggga ttacaggcgt
2521 gagccactgc acccggcctg cacgcgttct ttgaaagcag tcgagggggc gctaggtgtg
2581 ggcagggacg agctggcgcg gcgtcgctgg gtgcaccgcg accacgggca gagccacgcg
2641 gcgggaggac tacaactccc ggcacacccc gcgccgcccc gcctctactc ccagaaggcc
2701 gcggggggtg gaccgcctaa gagggcgtgc gctcccgaca tgccccgcgg cgcgccatta
2761 accgccagat ttgaatcgcg ggacccgttg gcagaggtgg cggcggcggc atgggtgccc
2821 cgacgttgcc ccctgcctgg cagccctttc tcaaggacca ccgcatctct acattcaaga
2881 actggccctt cttggagggc tgcgcctgca ccccggagcg ggtgagactg cccggcctcc
2941 tggggtcccc cacgcccgcc ttgccctgtc cctagcgagg ccactgtgac tgggcctcgg
3001 gggtacaagc cgccctcccc tccccgtcct gtccccagcg aggccactgt ggctgggccc
3061 cttgggtcca ggccggcctc ccctccctgc tttgtcccca tcgaggcctt tgtggctggg
3121 cctcggggtt ccgggctgcc acgtccactc acgagctgtg ctgtcccttg cagatggccg
3181 aggctggctt catccactgc cccactgaga acgagccaga cttggcccag tgtttcttct
3241 gcttcaagga gctggaaggc tgggagccag atgacgaccc catgtaagtc ttctctggcc
3301 agcctcgatg ggctttgttt tgaactgagt tgtcaaaaga tttgagttgc aaagacactt
3361 agtatgggag ggttgctttc caccctcatt gcttcttaaa cagctgttgt gaacggatac
3421 ctctctatat gctggtgcct tggtgatgct tacaacctaa ttaaatctca tttgaccaaa
3481 atgccttggg gtggacgtaa gatgcctgat gcctttcatg ttcaacagaa tacatcagca
3541 gaccctgttg ttgtgaactc ccaggaatgt ccaagtgctt tttttgagat tttttaaaaa
3601 acagtttaat tgaaatataa cctacacagc acaaaaatta ccctttgaaa gtgtgcactt
3661 cacactttcg gaggctgagg cgggcggatc acctgaggtc aggagttcaa gacctgcctg
3721 gccaacttgg cgaaaccccg tctctactaa aaatacaaaa attagccggg catggtagcg
3781 cacgcccgta atcccagcta ctcgggaggc taaggcagga gaatcgcttg aacctgggag
3841 gcggaggttg cagtgagccg agattgtgcc aatgcactcc agcctcggcg acagagcgag
3901 actccgtcat aaaaataaaa aattgaaaaa aaaaaaagaa agaaagcata tacttcagtg
3961 ttgttctgga tttttttctt caagatgcct agttaatgac aatgaaattc tgtactcgga
4021 tggtatctgt ctttccacac tgtaatgcca tattcttttc tcaccttttt ttctgtcgga
4081 ttcagttgct tccacagctt taattttttt cccctggaga atcaccccag ttgtttttct
4141 ttttggccag aagagagtag ctgttttttt tcttagtatg tttgctatgg tggttatact
4201 gcatccccgt aatcactggg aaaagatcag tggtattctt cttgaaaatg aataagtgtt
4261 atgatatttt cagattagag ttacaactgg ctgtcttttt ggactttgtg tggccatgtt
4321 ttcattgtaa tgcagttctg gtaacggtga tagtcagtta tacagggaga ctcccctagc
4381 agaaaatgag agtgtgagct agggggtccc ttggggaacc cggggcaata atgcccttct
4441 ctgcccttaa tccttacagt gggccgggca cggtggctta cgcctgtaat accagcactt
4501 tgggaggccg aggcgggcgg atcacgaggt caggagatcg agaccatctt ggctaatacg
4561 gtgaaacccc gtctccacta aaaatacaaa aaattagccg ggcgtggtgg tgggcgcctg
4621 tagtcccagc tactcgggag gctgaggcag gagaatggcg tgaacccagg aggcggagct
4681 tgcagtgagc cgagattgca ccactgcact ccagcctggg cgacagaatg agactccgtc
4741 tcaaaaaaaa aaaaaaaaga aaaaaatctt tacagtggat tacataacaa ttccagtgaa
4801 atgaaattac ttcaaacagt tccttgagaa tgttggaggg atttgacatg taattccttt
4861 ggacatatac catgtaacac ttttccaact aattgctaag gaagtccaga taaaatagat
4921 acattagcca cacagatgtg gggggagatg tccacaggga gagagaaggt gctaagaggt
4981 gccatatggg aatgtggctt gggcaaagca ctgatgccat caacttcaga cttgacgtct
5041 tactcctgag gcagagcagg gtgtgcctgt ggagggcgtg gggaggtggc ccgtggggag
5101 tggactgccg ctttaatccc ttcagctgcc tttccgctgt tgttttgatt tttctagaga
5161 ggaacataaa aagcattcgt ccggttgcgc tttcctttct gtcaagaagc agtttgaaga
5221 attaaccctt ggtgaatttt tgaaactgga cagagaaaga gccaagaaca aaattgtatg
5281 tattgggaat aagaactgct caaaccctgt tcaatgtctt tagcactaaa ctacctagtc
5341 cctcaaaggg actctgtgtt ttcctcagga agcatttttt ttttttttct gagatagagt
5401 ttcactcttg ttgcccaggc tggagtgcaa tggtgcaatc ttggctcact gcaacctctg
5461 cctctcgggt tcaagtgatt ctcctgcctc agcctcccaa gtaactggga ttacagggaa
5521 gtgccaccac acccagctaa tttttgtatt tttagtagag atggggtttc accacattgc
5581 ccaggctggt cttgaactcc tgacctcgtg attcgcccac cttggcctcc caaagtgctg
5641 ggattacagg cgtgaaccac cacgcctggc tttttttttt ttgttctgag acacagtttc
5701 actctgttac ccaggctgga gtagggtggc ctgatctcgg atcactgcaa cctccgcctc
5761 ctgggctcaa gtgatttgcc tgcttcagcc tcccaagtag ccgagattac aggcatgtgc
5821 caccacaccc aggtaatttt tgtatttttg gtagagacga ggtttcacca tgttggccag
5881 gctggttttg aactcctgac ctcaggtgat ccacccgcct cagcctccca aagtgctgag
5941 attataggtg tgagccacca cacctggcct caggaagtat ttttattttt aaatttattt
6001 atttatttga gatggagtct tgctctgtcg cccaggctag agtgcagcga cgggatctcg
6061 gctcactgca agctccgccc cccaggttca agccattctc ctgcctcagc ctcccgagta
6121 gctgggacta caggcgcccg ccaccacacc cggctaattt ttttgtattt ttagtagaga
6181 cgggttttca ccgtgttagc caggagggtc ttgatctcct gacctcgtga tctgcctgcc
6241 tcggcctccc aaagtgctgg gattacaggt gtgagccacc acacccggct atttttattt
6301 ttttgagaca gggactcact ctgtcacctg ggctgcagtg cagtggtaca ccatagctca
6361 ctgcagcctc gaactcctga gctcaagtga tcctcccacc tcatcctcac aagtaattgg
6421 gactacaggt gcaccccacc atgcccacct aatttattta tttatttatt tatttatttt
6481 catagagatg agggttccct gtgttgtcca ggctggtctt gaactcctga gctcacggga
6541 tccttttgcc tgggcctccc aaagtgctga gattacaggc atgagccacc gtgcccagct
6601 aggaatcatt tttaaagccc ctaggatgtc tgtgtgattt taaagctcct ggagtgtggc
6661 cggtataagt atataccggt ataagtaaat cccacatttt gtgtcagtat ttactagaaa
6721 cttagtcatt tatctgaagt tgaaatgtaa ctgggcttta tttatttatt tatttattta
6781 tttattttta attttttttt ttgagacgag tctcactttg tcacccaggc tggagtgcag
6841 tggcacgatc tcggctcact gcaacctctg cctcccgggg tcaagcgatt ctcctgcctt
6901 agcctcccga gtagctggga ctacaggcac gcaccaccat gcctggctaa tttttgtatt
6961 tttagtagac ggggtttcac catgctggcc aagctggtct caaactcctg accttgtgat
7021 ctgcccgctt tagcctccca gagtgctggg attacaggca tgagccacca tgcgtggtct
7081 ttttaaaatt ttttgatttt tttttttttt gagacagagc cttgctctgt cgcccaggct
7141 ggagtgcagt ggcacgatct cagctcacta caagctccgc ctcccgggtt cacgccattc
7201 ttctgcctca gcctcctgag tagctgggac tacaggtgcc caccaccacg cctggctaat
7261 tttttttggt atttttatta gagacaaggt ttcatcatgt tggccaggct ggtctcaaac
7321 tcctgacctc aagtgatctg cctgcctcgg cctcccaaag cgctgagatt acaggtgtga
7381 tctactgcgc caggcctggg cgtcatatat tcttatttgc taagtctggc agccccacac
7441 agaataagta ctgggggatt ccatatcctt gtagcaaagc cctgggtgga gagtcaggag
7501 atgttgtagt tctgtctctg ccacttgcag actttgagtt taagccagtc gtgctcatgc
7561 tttccttgct aaatagaggt tagaccccct atcccatggt ttctcaggtt gcttttcagc
7621 ttgaaaattg tattcctttg tagagatcag cgtaaaataa ttctgtcctt atatgtggct
7681 ttattttaat ttgagacaga gtgtcactca gtcgcccagg ctggagtgtg gtggtgcgat
7741 cttggctcac tgcgacctcc acctcccagg ttcaagcgat tctcgtgcct caggctccca
7801 agtagctgag attataggtg tgtgccacca ggcccagcta acttttgtat ttttagtaga
7861 gacagggttt tgccatgttg gctaagctgg tctcgaactc ctggcctcaa gtgatctgcc
7921 cgccttggca tcccaaagtg ctgggattac aggtgtgaac caccacacct ggcctcaata
7981 tagtggcttt taagtgctaa ggactgagat tgtgttttgt caggaagagg ccagttgtgg
8041 gtgaagcatg ctgtgagaga gcttgtcacc tggttgaggt tgtgggagct gcagcgtggg
8101 aactggaaag tgggctgggg atcatctttt tccaggtcag gggtcagcca gcttttctgc
8161 agcgtgccat agaccatctc ttagccctcg tgggtcagag tctctgttgc atattgtctt
8221 ttgttgtttt tcacaacctt ttagaaacat aaaaagcatt cttagcccgt gggctggaca
8281 aaaaaaggcc atgacgggct gtatggattt ggcccagcag gcccttgctt gccaagccct
8341 gttttagaca aggagcagct tgtgtgcctg gaaccatcat gggcacaggg gaggagcaga
8401 gtggatgtgg aggtgtgagc tggaaaccag gtcccagagc gctgagaaag acagagggtt
8461 tttgcccttg caagtagagc aactgaaatc tgacaccatc cagttccaga aagccctgaa
8521 gtgctggtgg acgctgcggg gtgctccgct ctagggttac agggatgaag atgcagtctg
8581 gtagggggag tccactcacc tgttggaaga tgtgattaag aaaagtagac tttcagggcc
8641 gggcatggtg gctcacgcct gtaatcccag cactttggga ggccgaggcg ggtggatcac
8701 gaggtcagga gatcgagacc atcctggcta acatggtgaa accccgtctt tactaaaaat
8761 acaaaaaatt agctgggcgt ggtggcgggc gcctgtagtc ccagctactc gggaggctga
8821 ggcaggagaa tggcgtgaac ctgggaggtg gagcttgctg tgagccgaga tcgcgccact
8881 gcactccagc ctgggcgaca gagcgagact ccgtctcaaa aaaaaaaaaa aaagtaggct
8941 ttcatgatgt gtgagctgaa ggcgcagtag gcagaagtag aggcctcagt ccctgcagga
9001 gacccctcgg tctctatctc ctgatagtca gacccagcca cactggaaag aggggagaca
9061 ttacagcctg cgagaaaagt agggagattt aaaaactgct tggcttttat tttgaactgt
9121 tttttttgtt tgtttgtttt ccccaattca gaatacagaa tacttttatg gatttgtttt
9181 tattacttta attttgaaac aatataatct tttttttgtt gtttttttga gacagggtct
9241 tactctgtca cccaggctga gtgcagtggt gtgatcttgg ctcacctcag cctcgacccc
9301 ctgggctcaa atgattctcc cacctcagct tcccaagtag ctgggaccac aggtgcgtgt
9361 gttgcgctat acaaatcctg aagacaagga tgctgttgct ggtgatgctg gggattccca
9421 agatcccaga tttgatggca ggatgcccct gtctgctgcc ttgccagggt gccaggaggg
9481 cgctgctgtg gaagctgagg cccggccatc cagggcgatg cattgggcgc tgattcttgt
9541 tcctgctgct gcctcggtgc ttagcttttg aaacaatgaa ataaattaga accagtgtga
9601 aaatcgatca gggaataaat ttaatgtgga aataaactga acaacttagt tcttcataag
9661 agtttacttg gtaaatactt gtgatgagga caaaacgaag cactagaagg agaggcgagt
9721 tgtagacctg ggtggcagga gtgttttgtt tgttttcttt ggcagggtct tgctctgttg
9781 ctcaggctgg agtacagtgg cacaatcaca gctcactata gcctcgacct cctggactca
9841 agcaatcctc ctgcctcagc ctcccagtag ctgggactac aggcgcatgc caccatgcct
9901 ggctaatttt aaattttttt ttttctcttt tttgagatgg aatctcactc tgtcgcccag
9961 gctggagtgc agtggcgtga tctcggctga cggcaagctc cgcctcccag gttcactcca
10021 ttcgcctgcc tcagcctccc aagtagctgg gactacaggc gctgggatta caaacccaaa
10081 cccaaagtgc tgggattaca ggcgtgagcc actgcacccg gcctgttttg tctttcaata
10141 gcaagagttg tgtttgcttc gcccctacct ttagtggaaa aatgtataaa atggagatat
10201 tgacctccac attggggtgg ttaaattata gcatgtatgc aaaggagctt cgctaattta
10261 aggctttttt gaaagagaag aaactgaata atccatgtgt gtatatatat tttaaaagcc
10321 atggtcatct ttccatatca gtaaagctga ggctccctgg gactgcagag ttgtccatca
10381 cagtccatta taagtgcgct gctgggccag gtgcagtggc ttgtgcctga atcccagcac
10441 tttgggaggc caaggcagga ggattcattg agcccaggag ttttgaggcg agcctgggca
10501 atgtggccag acctcatctc ttcaaaaaat acacaaaaaa ttagccaggc atggtggcac
10561 gtgcctgtag tctcagctac tcaggaggct gaggtgggag gatcactttg agccttgcag
10621 gtcaaagctg cagtaagcca tgatcttgcc actgcattcc agcctggatg acagagcgag
10681 accctgtctc taaaaaaaaa aaaaaccaaa cggtgcactg ttttcttttt tcttatcaat
10741 ttattatttt taaattaaat tttcttttaa taatttataa attataaatt tatattaaaa
10801 aatgacaaat ttttattact tatacatgag gtaaaactta ggatatataa agtacatatt
10861 gaaaagtaat tttttggctg gcacagtggc tcacacctgt aatcccagca ctttgggagg
10921 ccgtggcggg cagatcacat gagatcatga gttcgagacc aacctgacca acatggagag
10981 accccatctc tactaaaaat acaaaattag ccggggtggt ggcgcatgcc tgtaatccca
11041 gctactcggg aggctgaggc aggagaatct cttgaacccg ggaggcagag gttgcggtga
11101 gccaagatcg tgcctttgca caccagccta ggcaacaaga gcgaaagtcc gtctcaaaaa
11161 aaaagtaatt ttttttaagt taacctctgt cagcaaacaa atttaaccca ataaaggtct
11221 ttgtttttta atgtagtaga ggagttaggg tttataaaaa atatggtagg gaagggggtc
11281 cctggatttg ctaatgtgat tgtcatttgc cccttaggag agagctctgt tagcagaatg
11341 aaaaaattgg aagccagatt cagggaggga ctggaagcaa aagaatttct gttcgaggaa
11401 gagcctgatg tttgccaggg tctgtttaac tggacatgaa gaggaaggct ctggactttc
11461 ctccaggagt ttcaggagaa aggtagggca gtggttaaga gcagagctct gcctagacta
11521 gctggggtgc ctagactagc tggggtgccc agactagctg gggtgcctag actagctggg
11581 tactttgagt ggctccttca gcctggacct cggtttcctc acctgtatag tagagatatg
11641 ggagcaccca gcgcaggatc actgtgaaca taaatcagtt aatggaggaa gcaggtagag
11701 tggtgctggg tgcataccaa gcactccgtc agtgtttcct gttattcgat gattaggagg
11761 cagcttaaac tagagggagt tgagctgaat caggatgttt gtcccaggta gctgggaatc
11821 tgcctagccc agtgcccagt ttatttaggt gctctctcag tgttccctga ttgttttttc
11881 ctttgtcatc ttatctacag gatgtgactg ggaagctctg gtttcagtgt catgtgtcta
11941 ttctttattt ccaggcaaag gaaaccaaca ataagaagaa agaatttgag gaaactgcga
12001 agaaagtgcg ccgtgccatc gagcagctgg ctgccatgga ttgaggcctc tggccggagc
12061 tgcctggtcc cagagtggct gcaccacttc cagggtttat tccctggtgc caccagcctt
12121 cctgtgggcc ccttagcaat gtcttaggaa aggagatcaa cattttcaaa ttagatgttt
12181 caactgtgct cctgttttgt cttgaaagtg gcaccagagg tgcttctgcc tgtgcagcgg
12241 gtgctgctgg taacagtggc tgcttctctc tctctctctc ttttttgggg gctcattttt
12301 gctgttttga ttcccgggct taccaggtga gaagtgaggg aggaagaagg cagtgtccct
12361 tttgctagag ctgacagctt tgttcgcgtg ggcagagcct tccacagtga atgtgtctgg
12421 acctcatgtt gttgaggctg tcacagtcct gagtgtggac ttggcaggtg cctgttgaat
12481 ctgagctgca ggttccttat ctgtcacacc tgtgcctcct cagaggacag tttttttgtt
12541 gttgtgtttt tttgtttttt ttttttggta gatgcatgac ttgtgtgtga tgagagaatg
12601 gagacagagt ccctggctcc tctactgttt aacaacatgg ctttcttatt ttgtttgaat
12661 tgttaattca cagaatagca caaactacaa ttaaaactaa gcacaaagcc attctaagtc
12721 attggggaaa cggggtgaac ttcaggtgga tgaggagaca gaatagagtg ataggaagcg
12781 tctggcagat actccttttg ccactgctgt gtgattagac aggcccagtg agccgcgggg
12841 cacatgctgg ccgctcctcc ctcagaaaaa ggcagtggcc taaatccttt ttaaatgact
12901 tggctcgatg ctgtggggga ctggctgggc tgctgcaggc cgtgtgtctg tcagcccaac
12961 cttcacatct gtcacgttct ccacacgggg gagagacgca gtccgcccag gtccccgctt
13021 tctttggagg cagcagctcc cgcagggctg aagtctggcg taagatgatg gatttgattc
13081 gccctcctcc ctgtcataga gctgcagggt ggattgttac agcttcgctg gaaacctctg
13141 gaggtcatct cggctgttcc tgagaaataa aaagcctgtc atttcaaaca ctgctgtgga
13201 ccctactggg tttttaaaat attgtcagtt tttcatcgtc gtccctagcc tgccaacagc
13261 catctgccca gacagccgca gtgaggatga gcgtcctggc agagacgcag ttgtctctgg
13321 gcgcttgcca gagccacgaa ccccagacct gtttgtatca tccgggctcc ttccgggcag
13381 aaacaactga aaatgcactt cagacccact tatttatgcc acatctgagt cggcctgaga
13441 tagacttttc cctctaaact gggagaatat cacagtggtt tttgttagca gaaaatgcac
13501 tccagcctct gtactcatct aagctgctta tttttgatat ttgtgtcagt ctgtaaatgg
13561 atacttcact ttaataactg ttgcttagta attggctttg tagagaagct ggaaaaaaat
13621 ggttttgtct tcaactcctt tgcatgccag gcggtgatgt ggatctcggc ttctgtgagc
13681 ctgtgctgtg ggcagggctg agctggagcc gcccctctca gcccgcctgc cacggccttt
13741 ccttaaaggc catccttaaa accagaccct catggctgcc agcacctgaa agcttcctcg
13801 acatctgtta ataaagccgt aggcccttgt ctaagcgcaa ccgcctagac tttctttcag
13861 atacatgtcc acatgtccat ttttcaggtt ctctaagttg gagtggagtc tgggaagggt
13921 tgtgaatgag gcttctgggc tatgggtgag gttccaatgg caggttagag cccctcgggc
13981 caactgccat cctggaaagt agagacagca gtgcccgctg cccagaagag accagcaagc
14041 caaactggag cccccattgc aggctgtcgc catgtggaaa gagtaactca caattgccaa
14101 taaagtctca tgtggtttta tctacttttt ttttcttttt cttttttttt gagacaaggc
14161 cttgccctcc caggctggag tgcagtggaa tgaccacagc tcaccgcaac ctcaaattct
14221 tgcgttcaag tgaacctccc actttagcct cccaagtagc tgggactaca ggcgcacgcc
14281 atcacacccg gctaattgaa aaattttttt ttttgtttag atggaatctc actttgttgc
14341 ccaggctggt ctcaaactcc tgggctcaag tgatcatcct gcttcagcgt ccgacttgtt
14401 ggtattatag gcgtgagcca ctgggcctga cctagctacc attttttaat gcagaaatga
14461 agacttgtag aaatgaaata acttgtccag gatagtcgaa taagtaactt ttagagctgg
14521 gatttgaacc caggcaatct ggctccagag ctgggccctc actgctgaag gacactgtca
14581 gcttgggagg gtggctatgg tcggctgtct gattctaggg agtgagggct gtctttaaag
14641 caccccattc cattttcaga cagctttgtc agaaaggctg tcatatggag ctgacacctg
14701 cctccccaag gcttccatag atcctctctg tacattgtaa ccttttattt tgaaatgaaa
14761 attcacagga agttgtaagg ctagtacagg ggatcc
//