LOCUS HSU74667 2215 bp mRNA linear HUM 05-NOV-1996
DEFINITION Human tat interactive protein (TIP60) mRNA, complete cds.
ACCESSION U74667
VERSION U74667.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 271 to 2215)
AUTHORS Kamine,J., Elangovan,B., Subramanian,T., Coleman,D. and
Chinnadurai,G.
TITLE Identification of a cellular protein that specifically interacts
with the essential cysteine region of the HIV-1 Tat transactivator
JOURNAL Virology 216 (2), 357-366 (1996)
PUBMED 8607265
REFERENCE 2 (bases 1 to 2215)
AUTHORS Elangovan,B., Boyd,J.M., Subramanian,T. and Chinnadurai,G.
TITLE Full cDNA sequence for the Tat interacting protein Tip60
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 2215)
AUTHORS Elangovan,B., Boyd,J.M., Subramanian,T. and Chinnadurai,G.
TITLE Direct Submission
JOURNAL Submitted (07-OCT-1996) Institute for Molecular Virology, St. Louis
University Health Sciences Center, 3681 Park Avenue, St. Louis, MO
63110, USA
FEATURES Location/Qualifiers
source 1..2215
/db_xref="H-InvDB:HIT000221248"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
gene 1..2215
/gene="TIP60"
misc_feature 1..355
/gene="TIP60"
/note="similar to EST with GenBank Accession Number
T09055"
CDS 242..1783
/gene="TIP60"
/note="interacts with HIV1 Tat; similar to
acetyltransferase; similar to yeast SAS2, SAS3 and human
MOZ, encoded by GenBank Accession Numbers U14548, Z23261
and U47742, respectively; similar to sequence with GenBank
Accession Number U40989"
/codon_start=1
/product="tat interactive protein"
/protein_id="AAB18236.1"
/translation="MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFY
VHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQAS
GKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPV
PSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVS
DRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCL
QRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTD
PFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYRKLLIEFSYEL
SKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISEITSI
KKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWS
KRGKW"
BASE COUNT 529 a 644 c 624 g 418 t
ORIGIN
1 actcagtaga ccgccactgg ctgtgcacgt tatggggttt ccacctaggg ctcggcctga
61 ggcttgtaac actccgtttt cccccgagtc acaggggcag tcttgcccct cgcagctggg
121 tcgcggtgtc tctcaaaggt ccccctctac aggggcttcg tgaggcccgg gcccacaggg
181 cgctcggtcc cggaagtgac gtctcccaga ggggccggaa gtggcagtgg agggagggaa
241 gatggcggag gtgggggaga taatcgaggg ctgccgccta cccgtgctgc ggcggaacca
301 ggacaacgaa gatgagtggc ccctggccga gatcctgagc gtgaaggaca tcagtggccg
361 gaagcttttc tacgtccatt acattgactt caacaaacgt ctggatgaat gggtgacgca
421 tgagcggctg gacctaaaga agatccagtt ccccaagaaa gaggccaaga cccccactaa
481 gaacggactt cctgggtccc gtcctggctc tccagagaga gaggtgccgg cctcggcgca
541 ggccagcggg aagaccttgc caatcccggt ccagatcaca ctccgcttca acctgcccaa
601 ggagcgggag gccattcccg gtggcgagcc tgaccagccg ctctcctcca gctcctgcct
661 gcagcccaac caccgctcaa cgaaacggaa ggtggaggtg gtttcaccag caactccagt
721 gcccagcgag acagccccgg cctcggtttt tccccagaat ggagccgccc gtagggcagt
781 ggcagcccag ccaggacgga agcgaaaatc gaattgtttg ggcactgatg aggactccca
841 ggacagctct gatggaatac cgtcagcacc acgcatgact ggcagcctgg tgtctgatcg
901 aagccacgac gacatcgtca cccggatgaa gaacattgag tgcattgagc tgggccggca
961 ccgcctcaag ccgtggtact tctccccgta cccacaggaa ctcaccacat tgcctgtcct
1021 ctacctgtgc gagttctgcc tcaagtacgg ccgtagtctc aagtgtcttc agcgtcattt
1081 gaccaagtgt gacctacgac atcctccagg caatgagatt taccgcaagg gcaccatctc
1141 cttctttgag attgatggac gtaagaacaa gagttattcc cagaacctgt gtcttttggc
1201 caagtgtttc cttgaccata agacactgta ctatgacaca gaccctttcc tcttctacgt
1261 catgacagag tatgactgta agggcttcca catcgtgggc tacttctcca aggagaaaga
1321 atcaacggaa gactacaatg tggcctgcat cctaaccctg cctccctacc agcgccgggg
1381 ctaccggaag ctgctgatcg agttcagcta tgaactctcc aaagtggaag ggaaaacagg
1441 gacccctgag aagcccctct cagaccttgg cctcctatcc tatcgaagct actggtccca
1501 gaccatcctg gagatcctga tggggctgaa gtcggagagc ggggagaggc cacagatcac
1561 catcaatgag attagtgaaa tcaccagcat caagaaggag gatgtcatct ccactctgca
1621 gtacctcaat ctcatcaact actacaaggg ccagtacatc ctcacactgt cagaggacat
1681 cgtggatggc catgagcggg ccatgctcaa gcggctcctg cggatcgact ccaagtgtct
1741 gcacttcact cccaaggact ggagcaagag ggggaagtgg tgaccagaca ctgcccactg
1801 cagtgccaag acggcagcag gactggggct gatagcccac cccgccccca ctgcagctcc
1861 cacaaagcac tctaagggag atggggctga ggacagctca aaaaggagag gacaggcctg
1921 cagggcccac ttgcccagca ccaaggcgag ctccgggctc agaccaactc caaggtcagc
1981 tggccacagc ccaggcctcc tctgaagcag ggaccagagg gagccaggca gctgtgtaca
2041 gtgagaaggg atccggatgg gggagctctg tacagagggc tggtgattgt aaaaatttct
2101 tttgtaaagt agaagttggg ggtggggtgg gtgctggctg caaaaatttc tggcttctct
2161 tacccctatt gcccccggca ataaattgtt tctatatgcc aaaaaaaaaa aaaaa
//