LOCUS HSU72066 3247 bp mRNA linear HUM 21-APR-1998
DEFINITION Homo sapiens CtBP interacting protein CtIP (CtIP) mRNA, complete
cds.
ACCESSION U72066
VERSION U72066.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3247)
AUTHORS Schaeper,U., Subramanian,T., Lim,L., Boyd,J.M. and Chinnadurai,G.
TITLE Interaction between a cellular protein that binds to the C-terminal
region of adenovirus E1A (CtBP) and a novel cellular protein is
disrupted by E1A through a conserved PLDLS motif
JOURNAL J. Biol. Chem. 273 (15), 8549-8552 (1998)
PUBMED 9535825
REFERENCE 2 (bases 1 to 3247)
AUTHORS Schaeper,U. and Chinnadurai,G.
TITLE Direct Submission
JOURNAL Submitted (20-SEP-1996) Institute for Molecular Virology, St. Louis
University Health Sciences Center, 3681 Park Avenue, St. Louis, MO
63110, USA
FEATURES Location/Qualifiers
source 1..3247
/db_xref="H-InvDB:HIT000221166"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
/note="expressed in multiple tissues and cell lines"
gene 1..3247
/gene="CtIP"
CDS 300..2993
/gene="CtIP"
/codon_start=1
/product="CtBP interacting protein CtIP"
/protein_id="AAC14371.1"
/translation="MNILGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTK
LKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKK
QQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVI
PDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPN
ENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMS
PLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATS
SIKSGLDLNTSLSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGS
EVNKIIIQSSNKQILINKNISESLGEQNRTEYGKDSNTDKHLEPLKSLGGRTSKRKKT
EEESEHEVSCPQASFDKENAFPFPMDNQFSMNGDCVMDKPLDLSDRFSAIQRQEKSQG
SETSKNKFRQVTLYEALKTIPKGFSSSRKASDGNCTLPKDSPGEPCSQECIILQPLNK
CSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIKSAGSHEPIKIQTRSDHGGCE
LASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKMDVTVIDTKDGSQSK
LGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCL
ADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEV
VRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRFRYIPPNTPENFWEVGF
PSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT"
misc_feature 1767..1781
/gene="CtIP"
/note="encodes PLDLS which is required for interaction
with the cellular protein CtBP; this motif is also found
in the CtBP-binding region of Adenovirus 2/5 E1A."
BASE COUNT 1132 a 618 c 677 g 820 t
ORIGIN
1 cgggtccggc cgctccgagc ccggccgcag cccccggctt aaagcgcggg ctgtccggag
61 ggtcggcttt cccaccgagg atttggcact ctggtgaggg ttttgggcga aagagaaaag
121 cgagcagccg tccttcacag cctcagaaag tgctcgcttc ccttcggggc tttcgcgaat
181 cccgaggcaa tctcggaggc ggtatttgac ctgtccaaag acgacttgat acctctataa
241 tgtaacagaa aaggtcagaa aatattaagc aagtagaagt gtggagcata ttaagcaaga
301 tgaacatctt gggaagcagc tgtggaagcc ctaactctgc agatacatct agtgacttta
361 aggacctttg gacaaaacta aaagaatgtc atgatagaga agtacaaggt ttacaagtaa
421 aagtaaccaa gctaaaacag gaacgaatct tagatgcaca aagactagaa gaattcttca
481 ccaaaaatca acagctgagg gaacagcaga aagtccttca tgaaaccatt aaagttttag
541 aagatcggtt aagagcaggc ttatgtgatc gctgtgcagt aactgaagaa catatgcgga
601 aaaaacagca agagtttgaa aatatccggc agcagaatct taaacttatt acagaactta
661 tgaatgaaag gaatactcta caggaagaaa ataaaaagct ttctgaacaa ctccagcaga
721 aaattgagaa tgatcaacag catcaagcag ctgagcttga atgtgaggaa gacgttattc
781 cagattcacc gataacagcc ttctcatttt ctggcgttaa ccggctacga agaaaggaga
841 acccccatgt ccgatacata gaacaaacac atactaaatt ggagcactct gtgtgtgcaa
901 atgaaatgag aaaagtttcc aagtcttcaa ctcatccaca acataatcct aatgaaaatg
961 aaattctagt agctgacact tatgaccaaa gtcaatctcc aatggccaaa gcacatggaa
1021 caagcagcta tacccctgat aagtcatctt ttaatttagc tacagttgtt gctgaaacac
1081 ttggacttgg tgttcaagaa gaatctgaaa ctcaaggtcc catgagcccc cttggtgatg
1141 agctctacca ctgtctggaa ggaaatcaca agaaacagcc ttttgaggaa tctacaagaa
1201 atactgaaga tagtttaaga ttttcagatt ctacttcaaa gactcctcct caagaagaat
1261 tacctactcg agtgtcatct cctgtatttg gagctacctc tagtatcaaa agtggtttag
1321 atttgaatac aagtttgtcc ccttctcttt tacagcctgg gaaaaaaaaa catctgaaaa
1381 cactcccttt tagcaacact tgtatatcta gattagaaaa aactagatca aaatctgaag
1441 atagtgccct tttcacacat cacagtcttg ggtctgaagt gaacaagatc attatccagt
1501 catctaataa acagatactt ataaataaaa atataagtga atccctaggt gaacagaata
1561 ggactgagta cggtaaagat tctaacactg ataaacattt ggagcccctg aaatcattgg
1621 gaggccgaac atccaaaagg aagaaaactg aggaagaaag tgaacatgaa gtaagctgcc
1681 cccaagcttc ttttgataaa gaaaatgctt tcccttttcc aatggataat cagttttcca
1741 tgaatggaga ctgtgtgatg gataaacctc tggatctgtc tgatcgattt tcagctattc
1801 agcgtcaaga gaaaagccaa ggaagtgaga cttctaaaaa caaatttagg caagtgactc
1861 tttatgaggc tttgaagacc attccaaagg gcttttcctc aagccgtaag gcctcagatg
1921 gcaactgcac gttgcccaaa gattccccag gggagccctg ttcacaggaa tgcatcatcc
1981 ttcagccctt gaataaatgc tctccagaca ataaaccatc attacaaata aaagaagaaa
2041 atgctgtctt taaaattcct ctacgtccac gtgaaagttt ggagactgag aatgttttag
2101 atgacataaa gagtgctggt tctcatgagc caataaaaat acaaaccagg tcagaccatg
2161 gaggatgtga acttgcatca gttcttcagt taaatccatg tagaactggt aaaataaagt
2221 ctctacaaaa caaccaagat gtatcctttg aaaatatcca gtggagtata gatccgggag
2281 cagacctttc tcagtataaa atggatgtta ctgtaataga tacaaaggat ggcagtcagt
2341 caaaattagg aggagagaca gtggacatgg actgtacatt ggttagtgaa accgttctct
2401 taaaaatgaa gaagcaagag cagaagggag aaaaaagttc aaatgaagaa agaaaaatga
2461 atgatagctt ggaagatatg tttgatcgga caacacatga agagtatgaa tcctgtttgg
2521 cagacagttt ctcccaagca gcagatgaag aggaggaatt gtctactgcc acaaagaaac
2581 tacacactca tggtgataaa caagacaaag tcaagcagaa agcgtttgtg gagccgtatt
2641 ttaaaggtga tgaaagagag actagcttgc aaaattttcc tcatattgag gtggttcgga
2701 aaaaagagga gagaagaaaa ctgcttgggc acacgtgtaa ggaatgtgaa atttattatg
2761 cagatatgcc agcagaagaa agagaaaaga aattggcttc ctgctcaaga caccgattcc
2821 gctacattcc acccaacaca ccagagaatt tttgggaagt tggttttcct tccactcaga
2881 cttgtatgga aagaggttat attaaggaag atcttgatcc ttgtcctcgt ccaaaaagac
2941 gtcagcctta caacgcaata ttttctccaa aaggcaagga gcagaagaca tagacgttga
3001 aacagaaaca gaaggatgaa ggacagtttt ttccttctta gttatttata gttaaagttg
3061 gtactaaaca ttgatttttt tgatcttctg taaatggatt tataaatcag ttttctattg
3121 aaaatgtttg tgatattttg cttttgcacc tttaaaacaa taaggcgctt tcattttgca
3181 ctctaactta agagttttta ctttatgtag tgatacctaa tacaattttg aaaatacaaa
3241 aaaaaaa
//