LOCUS HSU69883 2535 bp mRNA linear HUM 25-OCT-1999
DEFINITION Homo sapiens small-conductance, calcium-activated potassium channel
SK1 (KCNN1) mRNA, complete cds.
ACCESSION U69883 AF131937
VERSION U69883.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2535)
AUTHORS Kohler,M., Hirschberg,B., Bond,C.T., Kinzie,J.M., Marrion,N.V.,
Maylie,J. and Adelman,J.P.
TITLE Small-conductance, calcium-activated potassium channels from
mammalian brain
JOURNAL Science 273 (5282), 1709-1714 (1996)
PUBMED 8781233
REFERENCE 2 (bases 1 to 2535)
AUTHORS Litt,M., LaMorticella,D., Bond,C.T. and Adelman,J.P.
TITLE Gene structure and chromosome mapping of the human
small-conductance calcium-activated potassium channel SK1 gene
(KCNN1)
JOURNAL Cytogenet. Cell Genet. 86 (1), 70-73 (1999)
PUBMED 10516439
REFERENCE 3 (bases 267 to 1952)
AUTHORS Bond,C.T., Maylie,J. and Adelman,J.P.
TITLE Direct Submission
JOURNAL Submitted (09-SEP-1996) Vollum Institute, Oregon Health Sciences
University, 3181 SW Sam Jackson Park Road, Portland, OR 97201-3098,
USA
REFERENCE 4 (bases 1 to 2535)
AUTHORS Bond,C.T., Maylie,J. and Adelman,J.P.
TITLE Direct Submission
JOURNAL Submitted (25-OCT-1999) Vollum Institute, Oregon Health Sciences
University, 3181 SW Sam Jackson Park Road, Portland, OR 97201-3098,
USA
REMARK Sequence update by submitter
COMMENT On Oct 25, 1999 this sequence version replaced U69883.1.
FEATURES Location/Qualifiers
source 1..2535
/db_xref="H-InvDB:HIT000221083"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="between WI-9679 and WI-3165"
/tissue_type="hippocampus"
gene 1..2535
/gene="KCNN1"
5'UTR <1..266
/gene="KCNN1"
CDS 267..1952
/gene="KCNN1"
/codon_start=1
/product="small-conductance, calcium-activated potassium
channel SK1"
/protein_id="AAB09562.1"
/translation="MPGPRAACSEPNPCTQVVMNSHSYNGSVGRPLGSGPGALGRDPP
DPEAGHPPQPPHSPGLQVVVAKSEPARPSPGSPRGQPQDQDDDEDDEEDEAGRQRASG
KPSNVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLYSFAL
KCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIHP
VPGHYRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSR
SIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSN
FLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKA
EKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIH
QAQKLRSVKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLD
ALGASLQALPGLIAQAIRPPPPPLPPRPGPGPQDQAARSSPCRWTPVAPSDCG"
3'UTR 1953..>2535
/gene="KCNN1"
BASE COUNT 492 a 854 c 770 g 419 t
ORIGIN
1 gaattccggg gtggtctgag ctggagccac gctttctgtt ggagggggca gctgaaggag
61 aacagcaaga catatccggc ggccctacgg actcggagag ctggagggac cccggagatc
121 tcaaagggac aggaaaggca gcagcagcca ccctctctcc cagtcaagtg gtcaccagca
181 ggactgaagg ggacagcccc tttgcagtgg ctcggcgagg agacccctgc accctagggt
241 cagtgcagga gcccagccgc tgagccatgc cgggtccccg ggcggcctgc agcgagccca
301 acccctgcac ccaggtagtc atgaacagcc acagctacaa tggcagcgtg gggcggccgc
361 tgggcagcgg gccgggcgcc ctgggacgag accctccgga ccctgaggcc ggccaccccc
421 cacaaccccc gcacagcccg ggcctccagg tggtagtggc caagagtgag ccagcccggc
481 cctcacccgg cagcccccgg gggcagcccc aggaccagga cgatgacgag gatgatgagg
541 aagatgaggc cggcaggcag agagcctcgg ggaaaccctc aaatgtgggc caccgcctgg
601 gccaccggcg ggcgctcttc gagaagcgga agcgcctcag cgactatgcc ctcattttcg
661 gcatgtttgg catcgtcgtc atggtgacgg agaccgagct gtcctggggg gtgtacacca
721 aggagtctct gtactcattc gcactcaaat gcctcatcag cctctccacg gccatcctgc
781 tgggtctcgt tgtcctctac catgcccggg agatccagct gttcatggtg gacaacgggg
841 ctgatgactg gcgcatcgcc atgacctgcg agcgcgtgtt cctcatctcg ctagagctgg
901 cagtgtgcgc cattcacccg gtgcccggcc actaccgctt cacgtggacg gcgcggctgg
961 ccttcacgta cgcgccctcg gtggccgagg ccgacgtgga cgtgctgctg tccatcccca
1021 tgttcctgcg cctctacctg ctgggccggg tgatgctact gcacagcaaa atcttcacgg
1081 acgcctcgag ccgcagcatc ggggccctca acaagatcac cttcaacacg cgcttcgtca
1141 tgaagacact catgaccatc tgccccggca ccgtgctgct ggtcttcagc atctcctcct
1201 ggatcatcgc agcctggacc gtgcgcgtct gcgagaggta ccacgacaag caggaagtga
1261 ccagcaactt cctgggggcc atgtggctga tttccatcac cttcctctcc attggctacg
1321 gcgacatggt gccccacacc tactgcggga agggtgtgtg cctgctcact ggcatcatgg
1381 gagctggctg taccgcgctc gtggtggctg tggtggctcg gaagctggag ctcaccaagg
1441 ctgagaagca cgtgcacaac ttcatgatgg acactcagct caccaagcgg gtaaaaaacg
1501 ccgctgctaa cgttctcagg gagacgtggc tcatctacaa acataccagg ctggtgaaga
1561 agccagacca agcccgggtt cggaaacacc agcgtaagtt cctccaagcc atccatcagg
1621 ctcagaagct ccggagtgtg aagatcgagc aagggaagct gaacgaccag gctaacacgc
1681 ttaccgacct agccaagacc cagaccgtca tgtacgacct tgtatcggag ctgcacgctc
1741 agcacgagga gctggaggcc cgcctggcca ccctggaaag ccgcttggat gcgctgggtg
1801 cctctctaca ggccctgcct ggcctcatcg cccaagccat acgcccaccc ccgcctcccc
1861 tgcctcccag gcccggcccc ggcccccaag accaggcagc ccggagctcc ccctgccggt
1921 ggacgcccgt ggccccctcg gactgcgggt gacggccctg cccgccacca gacccctaaa
1981 tcttggccat cgtgtggccg ccacctccgg gaagccttgt acagtggcgc ctcttggagt
2041 tcaagaagcc gacgctgagt caggctgagt ggactgaggc ctgccccgcc cagactgccc
2101 aggcagaggg cagggctgga ccatgggtga gggcagggga gcccggagct tcctctggtc
2161 acctggtccc ccgactctcc ccaggccccc ggtgggcatg gagcagcccg gggaggggtc
2221 cgtgctggtt ctgaataaag caggacccgc ctagtggctg cctgtgtgca tggctggaag
2281 gcactggtga tgtcccagga ggtagacctc cagccctggg taccaagatg aatgtgggaa
2341 tcagaaaaac ctgttcccat caccggccta gcctagaatc ctagcctaga agccctctct
2401 ccctctggct ggagctcagt agggacaact ctctagggac acctgtacca gccccacctg
2461 gcgctgagat ccctcagaca gcatggccca gccctggcca gaagcatcgc tccccttcaa
2521 ccaaccgcgt tgatg
//