LOCUS HSU68532 1963 bp mRNA linear HUM 14-OCT-1998
DEFINITION Homo sapiens cyclic AMP specific phosphodiesterase RD1 (PDE4a)
mRNA, complete cds.
ACCESSION U68532
VERSION U68532.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1963)
AUTHORS Sullivan,M., Rena,G., Begg,F., Gordon,L., Olsen,A.S. and
Houslay,M.D.
TITLE Identification and characterization of the human homologue of the
short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by
analysis of the human HSPDE4A gene locus located at chromosome
19p13.2
JOURNAL Biochem. J. 333 (Pt 3), 693-703 (1998)
PUBMED 9677330
REFERENCE 2 (bases 1 to 1963)
AUTHORS Houslay,M.D. and Sullivan,M.
TITLE Direct Submission
JOURNAL Submitted (30-AUG-1996) Biochemistry, University of Glasgow,
University Avenue, Glasgow G12 8QQ, Scotland, UK
REFERENCE 3 (bases 1 to 1963)
AUTHORS Houslay,M.D. and Sullivan,M.
TITLE Direct Submission
JOURNAL Submitted (14-OCT-1998) Biochemistry, University of Glasgow,
University Avenue, Glasgow G12 8QQ, Scotland, UK
REMARK Sequence update by submitter
COMMENT On Oct 14, 1998 this sequence version replaced gi:1527236.
FEATURES Location/Qualifiers
source 1..1963
/db_xref="H-InvDB:HIT000221054"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p13.2"
/cell_line="CCRF-CEM"
/cell_type="T lymphoblastoid"
gene 1..1963
/gene="PDE4a"
CDS 9..1952
/gene="PDE4a"
/codon_start=1
/product="cyclic AMP specific phosphodiesterase RD1"
/protein_id="AAC63832.1"
/translation="MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQV
SEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKL
MHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIF
QERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAV
FTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQ
EDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMC
DKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSP
PPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALD
ATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVA
VSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACA
GTFGEDTSALPAPGGGGSGGDPT"
BASE COUNT 457 a 595 c 553 g 358 t
ORIGIN
1 gatccaccat gcctttggtg gatttcttct gcgagacctg ctctaagcct tggctggtgg
61 gctggtggga ccagtttaaa aggatgttga accgtgagct cacacacctg tcagaaatga
121 gcaggtccgg aaaccaggtc tcagagtaca tttccacaac attcctggac aaacagaatg
181 aagtggagat cccatcaccc acgatgaagg aacgagaaaa acagcaagcg ccgcgaccaa
241 gaccctccca gccgcccccg ccccctgtac cacacttaca gcccatgtcc caaatcacag
301 ggttgaaaaa gttgatgcat agtaacagcc tgaacaactc taacattccc cgatttgggg
361 tgaagaccga tcaagaagag ctcctggccc aagaactgga gaacctgaac aagtggggcc
421 tgaacatctt ttgcgtgtcg gattacgctg gaggccgctc actcacctgc atcatgtaca
481 tgatattcca ggagcgggac ctgctgaaga aattccgcat cccggtggac acgatggtga
541 catacatgct gacgctggag gatcactacc acgctgacgt ggcctaccat aacagcctgc
601 acgcagctga cgtgctgcag tccacccacg tactgctggc cacgcctgca ctagatgcag
661 tgttcacgga cctggagatt ctcgccgccc tcttcgcggc tgccatccac gatgtggatc
721 accctggggt ctccaaccag ttcctcatca acaccaattc ggagctggcg ctcatgtaca
781 acgatgagtc ggtgctcgag aatcaccacc tggccgtggg cttcaagctg ctgcaggagg
841 acaactgcga catcttccag aacctcagca agcgccagcg gcagagccta cgcaagatgg
901 tcatcgacat ggtgctggcc acggacatgt ccaagcacat gaccctcctg gctgacctga
961 agaccatggt ggagaccaag aaagtgacca gctcaggggt cctcctgcta gataactact
1021 ccgaccgcat ccaggtcctc cggaacatgg tgcactgtgc cgacctcagc aaccccacca
1081 agccgctgga gctgtaccgc cagtggacag accgcatcat ggccgagttc ttccagcagg
1141 gtgaccgaga gcgcgagcgt ggcatggaaa tcagccccat gtgtgacaag cacactgcct
1201 ccgtggagaa gtctcaggtg ggttttattg actacattgt gcacccattg tgggagacct
1261 gggcggacct tgtccaccca gatgcccagg agatcttgga cactttggag gacaaccggg
1321 actggtacta cagcgccatc cggcagagcc catctccgcc acccgaggag gagtcaaggg
1381 ggccaggcca cccacccctg cctgacaagt tccagtttga gctgacgctg gaggaggaag
1441 aggaggaaga aatatcaatg gcccagatac cgtgcacagc ccaagaggca ttgactgcgc
1501 agggattgtc aggagtcgag gaagctctgg atgcaaccat agcctgggag gcatccccgg
1561 cccaggagtc gttggaagtt atggcacagg aagcatccct ggaggccgag ctggaggcag
1621 tgtatttgac acagcaggca cagtccacag gcagtgcacc tgtggctccg gatgagttct
1681 cgtcccggga ggaattcgtg gttgctgtaa gccacagcag cccctctgcc ctggctcttc
1741 aaagccccct tctccctgct tggaggaccc tgtctgtttc agagcatgcc ccgggcctcc
1801 cgggcctccc ctccacggcg gccgaggtgg aggcccaacg agagcaccag gctgccaaga
1861 gggcttgcag tgcctgcgca gggacatttg gggaggacac atccgcactc ccagctcctg
1921 gtggcggggg gtcaggtgga gaccctacct gatccccaga cct
//