LOCUS HSU68140 2907 bp mRNA linear HUM 17-SEP-1997
DEFINITION Homo sapiens nuclear VCP-like protein NVLp.2 (NVL.2) mRNA, complete
cds.
ACCESSION U68140
VERSION U68140.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2907)
AUTHORS Germain-Lee,E.L., Obie,C. and Valle,D.
TITLE NVL: a new member of the AAA family of ATPases localized to the
nucleus
JOURNAL Genomics 44 (1), 22-34 (1997)
PUBMED 9286697
REFERENCE 2 (bases 1 to 2907)
AUTHORS Germain-Lee,E.L., Obie,C. and Valle,D.
TITLE Direct Submission
JOURNAL Submitted (27-AUG-1996) Pediatrics, Johns Hopkins Med, 600 N. Wolfe
St, Baltimore, MD 21287, USA
FEATURES Location/Qualifiers
source 1..2907
/db_xref="H-InvDB:HIT000221041"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q41-1q42.2"
/tissue_type="kidney"
gene 1..2907
/gene="NVL.2"
/note="alternatively spliced"
CDS 57..2627
/gene="NVL.2"
/note="NVLP; AAA protein; VCP=valosin-containing protein"
/codon_start=1
/product="nuclear VCP-like protein NVLp.2"
/protein_id="AAB70457.1"
/translation="MKPRPAGFVDNKLKQRVIQYLTSNKCGKYVDIGVLASDLQRVYS
IDYGRRKRNAFRIQVEKVFSIISSEKELKNLTELEDEHLAKRARQGEEDNEYTESYSD
DDSSMEDYPDPQSANHMNSSLLSLYRKGNPDSVSNTPEMEQRETTSSTPRISSKTGSI
PLKTPAKDSEGGWFIDKTPSVKKDSFFLDLSCEKSNPKKPITEIQDSKDSSLLESDMK
RKGKLKNKGSKRKKEDLQEVDGEIEAVLQKKAKARGLEFQISNVKFEDVGGNDMTLKE
VCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGELDLPILKVAAPEI
VSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMERRIVAQLLTCM
DDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRERILQTLCRK
LRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAVNRVLMKLQEQQKKNPEMEDLPS
KGVQEERLGTEPTSETQDELQRLLGLLRDQDPLSEEQMQGLCIELNDFIVALSSVQPS
AKREGFVTVPNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPP
GCGKTLLAKAVANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDE
VDALCPRRSDRETGASVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRL
DKTLFVGLPPPADRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVR
EASICALRQEMARQKSGNEKGELKVSHKHFEEAFKKVRSSISKKDQIMYERLQESLSR
"
BASE COUNT 891 a 607 c 709 g 700 t
ORIGIN
1 cgcccccggt tgactaggag ctggcggtcc gagctgtggc ttgaaagacc gacgcgatga
61 agcccagacc tgcagggttc gtggataata aactcaagca gcgagtcatc cagtacctta
121 ccagtaacaa atgtggcaaa tatgtggaca ttggagtctt agcgtctgat ttacaaagag
181 tgtacagtat agactatggt cgaagaaaaa gaaatgcttt taggattcag gtagaaaaag
241 tatttagcat aattagtagt gagaaggaac ttaagaattt aacagaatta gaagatgaac
301 atttggcaaa aagggcaaga caaggtgaag aggataatga gtatactgaa agctattctg
361 atgatgattc aagtatggaa gactacccag atccacagtc agcaaatcac atgaacagtt
421 ccctgctgtc tttatatcgg aaaggaaatc ctgattctgt ttcaaatact cctgagatgg
481 agcaaagaga aaccacctct tcaacaccac gaataagttc caaaacaggc tccattccct
541 tgaagacccc tgccaaagat tctgaaggag gatggtttat tgacaaaacc ccaagtgtaa
601 agaaagacag ttttttcttg gacctgtcat gtgagaaaag taatcctaag aagccaataa
661 ctgagataca ggattcaaaa gattcttctc ttttggagag tgatatgaaa cggaaaggca
721 agctaaagaa taaaggaagc aaaaggaaga aagaagatct tcaggaagta gatggagaaa
781 ttgaagctgt cctacaaaag aaagctaaag ccagggggtt agaattccag atctccaacg
841 tgaagtttga agatgtggga ggcaatgata tgacattaaa agaggtctgc aagatgctca
901 tacacatgcg tcacccggag gtgtaccacc acctgggcgt cgtgccccct cgtggagttc
961 tccttcatgg accaccaggc tgtgggaaga cattacttgc acatgcaatt gctggggaac
1021 ttgacctgcc aattttgaaa gtggctgctc cagagattgt gtctggagta tccggagagt
1081 ctgagcagaa gctgagagaa ctatttgagc aagctgtgtc aaatgcacca tgtatcattt
1141 tcattgatga aattgatgct attaccccca aaagagaagt ggcttcaaaa gatatggaac
1201 gaagaattgt agcccaactc ctaacctgca tggatgatct gaataatgtg gctgctacag
1261 cccgggtcct agttattgga gctactaatc gaccagactc gttagaccct gctttgagac
1321 gtgcgggaag gttcgaccga gaaatatgcc taggtatccc agatgaagca tccagggaaa
1381 gaatacttca aacattgtgc agaaaactga ggcttcctca agcttttgat ttctgtcact
1441 tagcacacct aactccaggc tttgttggtg ctgatctcat ggcactgtgc cgagaggcag
1501 caatgtgtgc agtcaataga gtcttaatga agctacagga acagcagaag aaaaatcctg
1561 aaatggaaga tttgccatct aaaggagtcc aggaggaaag gctgggaact gagcccactt
1621 ctgaaacaca ggatgaatta caaaggctgc tggggttgct aagagaccaa gatcccctct
1681 cagaggagca gatgcaagga ctgtgcattg aactgaatga tttcattgtt gctctatcct
1741 cagtccaacc ctctgccaaa agggaaggct ttgtcactgt ccctaatgtg acatgggcag
1801 atattggtgc cctggaagac attagagagg agctcaccat ggcaatattg gcaccagtac
1861 gcaacccaga ccagttcaaa gctcttggat tggtgactcc agctggggtc ctccttgctg
1921 gtcctcctgg ctgtgggaag actctgctgg cgaaggctgt tgcaaatgag tccggactaa
1981 attttatatc tgtcaagggc cccgaattac taaacatgta tgttggtgag agtgaacgtg
2041 ctgtgcgaca agtttttcaa cgagccaaga actcagcacc ctgtgtgata ttctttgatg
2101 aagtggatgc tttatgtcct cgaagatcag accgagagac aggggcaagt gtccgagtgg
2161 tgaatcagct acttacagag atggatggtc tggaagcacg ccagcaggtt tttattatgg
2221 cagccactaa caggccagat ataattgacc ctgcaatcct gcgcccgggc cgcctggaca
2281 aaacactgtt tgtgggttta ccgccccctg cagatcgcct tgccatctta aaaactatca
2341 caaaaaatgg taccaaacca ccactggatg cagatgtaaa tttggaagca attgctggtg
2401 accttcgctg tgattgctat acgggcgcag atctctctgc tttggtacga gaagcttcta
2461 tctgtgccct gagacaggaa atggcaagac agaagagtgg aaatgaaaaa ggtgaactca
2521 aggttagtca taagcatttt gaagaagctt tcaagaaagt aagatcatct atatcaaaaa
2581 aggatcaaat catgtatgaa cgtttgcagg agtccctcag ccggtgatgt ctccagcagc
2641 cggcttagag gagctagccc atcaagccgg cagagaatcc cccacacgct ctgaaggacc
2701 cactttcagc tggacacagg cgcggcctca tgtaaacatt ttattttcaa atgaatgagg
2761 ccaagctgaa gctgaagctg aagattcttc ccatctggcc agccttgtgt gaaaatgcct
2821 tcttcctctt taagaaaaag gacaattttt aaactgctga aataaaatga ctgttacatt
2881 tttcaaataa aacttttact ttgaact
//