LOCUS HSU66497 4102 bp mRNA linear HUM 16-OCT-2000
DEFINITION Human leptin receptor splice variant form 13.2 mRNA, complete cds.
ACCESSION U66497
VERSION U66497.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4102)
AUTHORS Bennett,B.D., Solar,G.P., Yuan,J.Q., Mathias,J., Thomas,G.R. and
Matthews,W.
TITLE A role for leptin and its cognate receptor in hematopoiesis
JOURNAL Curr. Biol. 6 (9), 1170-1180 (1996)
PUBMED 8805376
REFERENCE 2 (bases 1 to 4102)
AUTHORS Bennett,B.D., Solar,G.P., Yuan,J.Q., Mathias,J., Thomas,G.R. and
Matthews,W.
TITLE Direct Submission
JOURNAL Submitted (09-AUG-1996) Molecular Oncology, Genentech Inc., 460 Pt.
San Bruno Blvd, South San Francisco, CA 92080, USA
FEATURES Location/Qualifiers
source 1..4102
/db_xref="H-InvDB:HIT000220946"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="13.2"
CDS 127..3624
/note="splice variant form 13.2; Ob receptor"
/codon_start=1
/product="leptin receptor"
/protein_id="AAB07497.1"
/translation="MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTY
DYFLLPAGLSKNTSNSNGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLC
ADNIEGKTFVSTVNSLVFQQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVH
LLYVLPEVLEDSPLVPQKGSFQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSG
GVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSEN
STTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVI
YFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVT
FFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLTKMTCRWS
TSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSG
YTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPEN
NLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSN
WSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVIN
HHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNI
VQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNEDGEIKWLRISSSVKKYYIH
DHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGLYVIVPVIISSSILL
LGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTASVTCGPLLLE
PETISEDISVDTSWKNKDEMMPTTVVSLLSTTDLEKGSVCISDQFNSVNFSEAEGTEV
TYEDESQRQPFVKYATLISNSKPSETGEEQGLINSSVTKCFSSKNSPLKDSFSNSSWE
IEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYLGVTSIKKR
ESGVLLTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNINLGTSSKKTFASYMPQFQ
TCSTQTHKIMENKMCDLTV"
BASE COUNT 1252 a 759 c 810 g 1281 t
ORIGIN
1 gaattctcga gtcgacggcg ggcgttaaag ctctcgtggc attatccttc agtggggcta
61 ttggactgac ttttcttatg ctgggatgtg ccttagagga ttatgggtgt acttctctga
121 agtaagatga tttgtcaaaa attctgtgtg gttttgttac attgggaatt tatttatgtg
181 ataactgcgt ttaacttgtc atatccaatt actccttgga gatttaagtt gtcttgcatg
241 ccaccaaatt caacctatga ctacttcctt ttgcctgctg gactctcaaa gaatacttca
301 aattcgaatg gacattatga gacagctgtt gaacctaagt ttaattcaag tggtactcac
361 ttttctaact tatccaaaac aactttccac tgttgctttc ggagtgagca agatagaaac
421 tgctccttat gtgcagacaa cattgaagga aagacatttg tttcaacagt aaattcttta
481 gtttttcaac aaatagatgc aaactggaac atacagtgct ggctaaaagg agacttaaaa
541 ttattcatct gttatgtgga gtcattattt aagaatctat tcaggaatta taactataag
601 gtccatcttt tatatgttct gcctgaagtg ttagaagatt cacctctggt tccccaaaaa
661 ggcagttttc agatggttca ctgcaattgc agtgttcatg aatgttgtga atgtcttgtg
721 cctgtgccaa cagccaaact caacgacact ctccttatgt gtttgaaaat cacatctggt
781 ggagtaattt tccagtcacc tctaatgtca gttcagccca taaatatggt gaagcctgat
841 ccaccattag gtttgcatat ggaaatcaca gatgatggta atttaaagat ttcttggtcc
901 agcccaccat tggtaccatt tccacttcaa tatcaagtga aatattcaga gaattctaca
961 acagttatca gagaagctga caagattgtc tcagctacat ccctgctagt agacagtata
1021 cttcctgggt cttcgtatga ggttcaggtg aggggcaaga gactggatgg cccaggaatc
1081 tggagtgact ggagtactcc tcgtgtcttt accacacaag atgtcatata ctttccacct
1141 aaaattctga caagtgttgg gtctaatgtt tcttttcact gcatctataa gaaggaaaac
1201 aagattgttc cctcaaaaga gattgtttgg tggatgaatt tagctgagaa aattcctcaa
1261 agccagtatg atgttgtgag tgatcatgtt agcaaagtta cttttttcaa tctgaatgaa
1321 accaaacctc gaggaaagtt tacctatgat gcagtgtact gctgcaatga acatgaatgc
1381 catcatcgct atgctgaatt atatgtgatt gatgtcaata tcaatatctc atgtgaaact
1441 gatgggtact taactaaaat gacttgcaga tggtcaacca gtacaatcca gtcacttgcg
1501 gaaagcactt tgcaattgag gtatcatagg agcagccttt actgttctga tattccatct
1561 attcatccca tatctgagcc caaagattgc tatttgcaga gtgatggttt ttatgaatgc
1621 attttccagc caatcttcct attatctggc tacacaatgt ggattaggat caatcactct
1681 ctaggttcac ttgactctcc accaacatgt gtccttcctg attctgtggt gaagccactg
1741 cctccatcca gtgtgaaagc agaaattact ataaacattg gattattgaa aatatcttgg
1801 gaaaagccag tctttccaga gaataacctt caattccaga ttcgctatgg tttaagtgga
1861 aaagaagtac aatggaagat gtatgaggtt tatgatgcaa aatcaaaatc tgtcagtctc
1921 ccagttccag acttgtgtgc agtctatgct gttcaggtgc gctgtaagag gctagatgga
1981 ctgggatatt ggagtaattg gagcaatcca gcctacacag ttgtcatgga tataaaagtt
2041 cctatgagag gacctgaatt ttggagaata attaatggag atactatgaa aaaggagaaa
2101 aatgtcactt tactttggaa gcccctgatg aaaaatgact cattgtgcag tgttcagaga
2161 tatgtgataa accatcatac ttcctgcaat ggaacatggt cagaagatgt gggaaatcac
2221 acgaaattca ctttcctgtg gacagagcaa gcacatactg ttacggttct ggccatcaat
2281 tcaattggtg cttctgttgc aaattttaat ttaacctttt catggcctat gagcaaagta
2341 aatatcgtgc agtcactcag tgcttatcct ttaaacagca gttgtgtgat tgtttcctgg
2401 atactatcac ccagtgatta caagctaatg tattttatta ttgagtggaa aaatcttaat
2461 gaagatggtg aaataaaatg gcttagaatc tcttcatctg ttaagaagta ttatatccat
2521 gatcatttta tccccattga gaagtaccag ttcagtcttt acccaatatt tatggaagga
2581 gtgggaaaac caaagataat taatagtttc actcaagatg atattgaaaa acaccagagt
2641 gatgcaggtt tatatgtaat tgtgccagta attatttcct cttccatctt attgcttgga
2701 acattattaa tatcacacca aagaatgaaa aagctatttt gggaagatgt tccgaacccc
2761 aagaattgtt cctgggcaca aggacttaat tttcagaagc cagaaacgtt tgagcatctt
2821 tttatcaagc atacagcatc agtgacatgt ggtcctcttc ttttggagcc tgaaacaatt
2881 tcagaagata tcagtgttga tacatcatgg aaaaataaag atgagatgat gccaacaact
2941 gtggtctctc tactttcaac aacagatctt gaaaagggtt ctgtttgtat tagtgaccag
3001 ttcaacagtg ttaacttctc tgaggctgag ggtactgagg taacctatga ggacgaaagc
3061 cagagacaac cctttgttaa atacgccacg ctgatcagca actctaaacc aagtgaaact
3121 ggtgaagaac aagggcttat aaatagttca gtcaccaagt gcttctctag caaaaattct
3181 ccgttgaagg attctttctc taatagctca tgggagatag aggcccaggc attttttata
3241 ttatcagatc agcatcccaa cataatttca ccacacctca cattctcaga aggattggat
3301 gaacttttga aattggaggg aaatttccct gaagaaaata atgataaaaa gtctatctat
3361 tatttagggg tcacctcaat caaaaagaga gagagtggtg tgcttttgac tgacaagtca
3421 agggtatcgt gcccattccc agccccctgt ttattcacgg acatcagagt tctccaggac
3481 agttgctcac actttgtaga aaataatatc aacttaggaa cttctagtaa gaagactttt
3541 gcatcttaca tgcctcaatt ccaaacttgt tctactcaga ctcataagat catggaaaac
3601 aagatgtgtg acctaactgt gtaatttcac tgaagaaacc ttcagatttg tgttataatg
3661 ggtaatataa agtgtaatag attatagttg tgggtgggag agagaaaaga aaccagagtc
3721 aaatttgaaa ataattgttc caaatgaatg ttgtctgttt gttctctctt agtaacatag
3781 acaaaaaatt tgagaaagcc ttcataagcc taccaatgta gacacgctct tctattttat
3841 tcccaagctc tagtgggaag gtcccttgtt tccagctaga aataagccca acagacacca
3901 tcttttgtga gatgtaattg ttttttcaga gggcgtgttg ttttacctca agtttttgtt
3961 ttgtaccaac acacacacac acacacattc ttaacacatg tccttgtgtg ttttgagagt
4021 atattatgta tttatatttt gtgctatcag actgtaggat ttgaagtagg actttcctaa
4081 atgtttaaga taaacagaat tc
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