LOCUS HSU65785 4503 bp mRNA linear HUM 24-JAN-1997
DEFINITION Human 150 kDa oxygen-regulated protein ORP150 mRNA, complete cds.
ACCESSION U65785
VERSION U65785.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4503)
AUTHORS Ikeda,J., Kaneda,S., Kuwabara,K., Ogawa,S., Kobayashi,T.,
Matsumoto,M., Yura,T. and Yanagi,H.
TITLE Cloning and expression of cDNA encoding the human 150 kDa
oxygen-regulated protein, ORP150
JOURNAL Biochem. Biophys. Res. Commun. 230 (1), 94-99 (1997)
PUBMED 9020069
REFERENCE 2 (bases 1 to 4503)
AUTHORS Ikeda,J., Kobayashi,T., Kuwabara,K., Ogawa,S., Yura,T. and
Yanagi,H.
TITLE Direct Submission
JOURNAL Submitted (01-AUG-1996) HSP Research Institute, Kyoto Research
Park, Shimogyo-ku, Kyoto 600, Japan
FEATURES Location/Qualifiers
source 1..4503
/db_xref="H-InvDB:HIT000220888"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="astrocytoma U373"
CDS 103..3102
/function="proposed ER chaperone"
/codon_start=1
/product="150 kDa oxygen-regulated protein ORP150"
/protein_id="AAC50947.1"
/translation="MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSES
MKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQH
LLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSL
AEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRR
KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEME
LRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM
DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRV
QEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVEFT
REVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDL
RVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVED
SAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKE
EAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPE
GEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAA
NSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKL
AELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTT
LEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKP
RPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKVETGSEPGDTEPL
ELGGPGAEPEQKEQSTGQKRPLKNDEL"
BASE COUNT 1045 a 1177 c 1311 g 970 t
ORIGIN
1 ttgtgaaggg cgcgggtggg gggcgctgcc ggcctcgtgg gtacgttcgt gccgcgtctg
61 tcccagagct ggggccgcag gagcggaggc aagaggggca ctatggcaga caaagttagg
121 aggcagaggc cgaggaggcg agtctgttgg gccttggtgg ctgtgctctt ggcagacctg
181 ttggcactga gtgatacact ggcagtgatg tctgtggacc tgggcagtga gtccatgaag
241 gtggccattg tcaaacctgg agtgcccatg gaaattgtct tgaataagga atctcggagg
301 aaaacaccgg tgatcgtgac cctgaaagaa aatgaaagat tctttggaga cagtgcagca
361 agcatggcga ttaagaatcc aaaggctacg ctacgttact tccagcacct cctggggaag
421 caggcagata acccccatgt agctctttac caggcccgct tcccggagca cgagctgact
481 ttcgacccac agaggcagac tgtgcacttt cagatcagct cgcagctgca gttctcacct
541 gaggaagtgt tgggcatggt tctcaattat tctcgttctc tagctgaaga ttttgcagag
601 cagcccatca aggatgcagt gatcaccgtg ccagtcttct tcaaccaggc cgagcgccga
661 gctgtgctgc aggctgctcg tatggctggc ctcaaagtgc tgcagctcat caatgacaac
721 accgccactg ccctcagcta tggtgtcttc cgccggaaag atattaacac cactgcccag
781 aatatcatgt tctatgacat gggctcaggc agcaccgtat gcaccattgt gacctaccag
841 atggtgaaga ctaaggaagc tgggatgcag ccacagctgc agatccgggg agtaggattt
901 gaccgtaccc tggggggcct ggagatggag ctccggcttc gagaacgcct ggctgggctt
961 ttcaatgagc agcgcaaggg tcagagagca aaggatgtgc gggagaaccc gcgtgccatg
1021 gccaagctgc tgcgtgaggc taatcggctc aaaaccgtcc tcagtgccaa cgctgaccac
1081 atggcacaga ttgaaggcct gatggatgat gtggacttca aggcaaaagt gactcgtgtg
1141 gaatttgagg agttgtgtgc agacttgttt gagcgggtgc ctgggcctgt acagcaggcc
1201 ctccagagtg ccgaaatgag tctggatgag attgagcagg tgatcctggt gggtggggcc
1261 actcgggtcc ccagagttca ggaggtgctg ctgaaggccg tgggcaagga ggagctgggg
1321 aagaacatca atgcagatga agcagccgcc atgggggcag tgtaccaggc agctgcgctc
1381 agcaaagcct ttaaagtgaa gccatttgtc gtccgagatg cagtggtcta ccccatcctg
1441 gtggagttca cgagggaggt ggaggaggag cctgggattc acagcctgaa gcacaataaa
1501 cgggtactct tctctcggat ggggccctac cctcaacgca aagtcatcac ctttaaccgc
1561 tacagccatg atttcaactt ccacatcaac tacggcgacc tgggcttcct ggggcctgaa
1621 gatcttcggg tatttggctc ccagaatctg accacagtga agctaaaagg ggtgggtgac
1681 agcttcaaga agtatcctga ctacgagtcc aagggcatca aggctcactt caacctggat
1741 gagagtggcg tgctcagtct agacagggtg gagtctgtat ttgagacact ggtagaggac
1801 agcgcagaag aggaatctac tctcaccaaa cttggcaaca ccatttccag cctgtttgga
1861 ggcggtacca caccagatgc caaggagaat ggtactgata ctgtccagga ggaagaggag
1921 agccctgcag aggggagcaa ggacgagcct ggggagcagg tggagctcaa ggaggaagct
1981 gaggccccag tggaggatgg ctctcagccc ccaccccctg aacctaaggg agatgcaacc
2041 cctgagggag aaaaggccac agaaaaagaa aatggggaca agtctgaggc ccagaaacca
2101 agtgagaagg cagaggcagg gcctgagggc gtcgctccag ccccagaggg agagaagaag
2161 cagaagcccg ccaggaagcg gcgaatggta gaggagatcg gggtggagct ggttgttctg
2221 gacctgcctg acttgccaga ggataagctg gctcagtcgg tgcagaaact tcaggacttg
2281 acactccgag acctggagaa gcaggaacgg gaaaaagctg ccaacagctt ggaagcgttc
2341 atatttgaga cccaggacaa gctgtaccag cccgagtacc aggaagtgtc cacagaggag
2401 cagcgtgagg agatctctgg gaagctcagc gccgcatcca cctggctgga ggatgagggt
2461 gttggagcca ccacagtgat gttgaaggag aagctggctg agctgaggaa gctgtgccaa
2521 gggctgtttt ttcgggtaga ggagcgcaag aagtggcccg aacggctgtc tgccctcgat
2581 aatctcctca accattccag catgttcctc aagggggccc ggctcatccc agagatggac
2641 cagatcttca ctgaggtgga gatgacaacg ttagagaaag tcatcaatga gacctgggcc
2701 tggaagaatg caactctggc cgagcaggct aagctgcccg ccacagagaa gcctgtgttg
2761 ctctcaaaag acattgaagc taagatgatg gccctggacc gagaggtgca gtatctgctc
2821 aataaggcca agtttaccaa gccccggccc cggcctaagg acaagaatgg gacccgggca
2881 gagccacccc tcaatgccag tgccagtgac cagggggaga aggtcatccc tccagcaggc
2941 cagactgaag atgcagagcc catttcagaa cctgagaaag tagagactgg atccgagcca
3001 ggagacactg agcctttgga gttaggaggt cctggagcag aacctgaaca gaaagaacaa
3061 tcgacaggac agaagcggcc tttgaagaac gacgaactat aacccccacc tctgttttcc
3121 ccattcatct ccaccccctt cccccaccac ttctatttat ttaacatcga gggttggggg
3181 aggggttggt cctgccctcg gctggagttc ctttctcacc cctgtgattt ggaggtgtgg
3241 agaaggggaa gggagggaca gctcactggt tccttctgca gtacctctgt ggttaaaaat
3301 ggaaactgtt ctcctcccca gccccactcc ctgttcccta cccatatagg ccctaaattt
3361 gggaaaaatc actattaatt tctgaatcct ttgcctgtgg gtaggaagag aatggctgcc
3421 agtggctgat gggtcccggt gatgggaagg gtatcaggtt gctggggagt ttccactctt
3481 ctctggtgat tgttccttcc ctcccttcct ctcccaccat gcgatgagca tcctttcagg
3541 ccagtgtctg cagagcctca gttaccaggt ttggtttctg agtgcctatc tgtgctcttt
3601 cctccctctg cgggcttctc ttgctctgag cctcccttcc ccattcccat gcagctcctt
3661 tccccctggg tttccttggc ttcctgcagc aaattgggca gttctctgcc ccttgcctaa
3721 aagcctgtac ctctggattg gcggaagtaa atctggaagg attctcactc gtatttccca
3781 cccctagtgg ccagaggagg gaggggcaca gtgaagaagg gagcccacca cctctccgaa
3841 gaggaaagcc acgtagagtg gttggcatgg ggtgccagca tcgtgcaagc tctgtcataa
3901 tctgcatctt cccagcagcc tggtacccca ggttcctgta actccctgcc tcctcctctc
3961 ttctgctgtt ctgctcctcc cagacagagc ctttccctca ccccctgacc ccctgggctg
4021 accaaaatgt gctttctact gtgagtccct atcccaagat cctggggaaa ggagagacca
4081 tggtgtgaat gtagagatgc cacctccctc tctctgaggc aggcctgtgg atgaaggagg
4141 agggtcaggg ctggccttcc tctgtgcatc actctgctag gttgggggcc cccgacccac
4201 catacctacg cctagggagc ccgtcctcca gtattccgtc tgtagcagga gctagggctg
4261 ctgcctcagc tccaagacaa gaatgaacct ggctgtgtca gtcattttgt cttttccttt
4321 tttttttttt gccacattgg cagagatggg acctaagggt cccacccctc accccacccc
4381 cacctcttct gtatgtttga attctttcag tagctgttga tgctggttgg acaggtttga
4441 gtcaaattgt actttgctcc attgttaatt gagaaactgt ttcaataaaa tattcttttc
4501 tac
//