LOCUS HSU65410 1484 bp mRNA linear HUM 30-OCT-1996
DEFINITION Human Mad2 (hsMAD2) mRNA, complete cds.
ACCESSION U65410
VERSION U65410.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1484)
AUTHORS Li,Y. and Benezra,R.
TITLE Identification of a human mitotic checkpoint gene: hsMAD2
JOURNAL Science 274 (5285), 246-248 (1996)
PUBMED 8824189
REFERENCE 2 (bases 1 to 1484)
AUTHORS Li,Y. and Benezra,R.
TITLE Direct Submission
JOURNAL Submitted (26-JUL-1996) Cell Biology and Genetics, Memorial
Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY
10021, USA
FEATURES Location/Qualifiers
source 1..1484
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1484
/gene="hsMAD2"
CDS 34..651
/gene="hsMAD2"
/function="required for the execution of the mitotic
checkpoint which monitors the process of
kinetochore-spindle attachment and delays the onset of
anaphase when this process is not complete"
/codon_start=1
/product="Mad2"
/protein_id="AAC50781.1"
/translation="MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFT
RVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQF
DIECDKTAKDDSAPREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKD
LVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYKIPVND"
BASE COUNT 445 a 260 c 317 g 462 t
ORIGIN
1 tggaagcgcg tgcttttgtt tgtgtccctg gccatggcgc tgcagctctc ccgggagcag
61 ggaatcaccc tgcgcgggag cgccgaaatc gtggccgagt tcttctcatt cggcatcaac
121 agcattttat atcagcgtgg catatatcca tctgaaacct ttactcgagt gcagaaatac
181 ggactcacct tgcttgtaac tactgatctt gagctcataa aatacctaaa taatgtggtg
241 gaacaactga aagattggtt atacaagtgt tcagttcaga aactggttgt agttatctca
301 aatattgaaa gtggtgaggt cctggaaaga tggcagtttg atattgagtg tgacaagact
361 gcaaaagatg acagtgcacc cagagaaaag tctcagaaag ctatccagga tgaaatccgt
421 tcagtgatca gacagatcac agctacggtg acatttctgc cactgttgga agtttcttgt
481 tcatttgatc tgctgattta tacagacaaa gatttggttg tacctgaaaa atgggaagag
541 tcgggaccac agtttattac caattctgag gaagtgcgcc ttcgttcatt tactactaca
601 atccacaaag taaatagcat ggtggcctac aaaattcctg tcaatgactg aggatgacat
661 gaggaaaata atgtaattgt aattttgaaa tgtggttttc ctgaaatcag gtcatctata
721 gttgatatgt tttatttcat tggttaattt ttacatggag aaaaccaaaa tgatacttac
781 tgaactgtgt gtaattgttc cttttatttt tttggtacct atttgactta ccatggagtt
841 aacatcatga atttattgca cattgttcaa aaggaaccag gaggtttttt tgtcaacatt
901 gtgatgtata ttcctttgaa gatagtaact gtagatggaa aaacttgtgc tataaagcta
961 gatgctttcc taaatcagat gttttggtca agtagtttga ctcagtatag gtagggagat
1021 atttaagtat aaaatacaac aaaggaagtc taaatattca gaatctttgt taaggtcctg
1081 aaagtaactc ataatctata aacaatgaaa tattgctgta tagctccttt tgaccttcat
1141 ttcatgtata gttttcccta ttgaatcagt ttccaattat ttgactttaa tttatgtaac
1201 ttgaacctat gaagcaatgg atatttgtac tgtttaatgt tctgtgatac agaacagatt
1261 aatactccct ttttatcatt acagttagct aaaaaattgc caggcagtcc acaaaacaga
1321 atttgcttta agaccaaccc acagagtcag ctggagacta acggcgctgg ggcctgctgg
1381 gccgggatat agtcgtgttt agctaagtgt cgagagcatt aagaagaaag tcctggttgg
1441 aggcgcaagg cctgcagcac cagctgtgga atccccaata atgt
//