LOCUS HSU64198 4040 bp mRNA linear HUM 28-NOV-2000
DEFINITION Human Il-12 receptor beta2 mRNA, complete cds.
ACCESSION U64198
VERSION U64198.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4040)
AUTHORS Presky,D.H., Yang,H., Minetti,L.J., Chua,A.O., Nabavi,N., Wu,C.Y.,
Gately,M.K. and Gubler,U.
TITLE A functional interleukin 12 receptor complex is composed of two
beta-type cytokine receptor subunits
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 93 (24), 14002-14007 (1996)
PUBMED 8943050
REFERENCE 2 (bases 1 to 4040)
AUTHORS Presky,D.H., Yang,H., Minetti,L.J., Chua,A.O., Nabavi,N.,
Wou,C.-Y., Gately,M.K. and Gubler,U.
TITLE Direct Submission
JOURNAL Submitted (17-JUL-1996) Inflammation/Autoimmune Diseases, Hoffmann
la Roche Inc, 340 Kingsland Street, Nutley, NJ 07110, USA
FEATURES Location/Qualifiers
source 1..4040
/db_xref="H-InvDB:HIT000220799"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 641..3229
/codon_start=1
/product="Il-12 receptor beta2"
/protein_id="AAB36675.1"
/translation="MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLG
STVNITCSLKPRQGCFHYSRRNKLILYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCK
LACINSDEIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQ
LSGPKNLTWQKQCKDIYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTF
LDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLVLLNRLRYRPSNSRLWNMVNVTKAK
GRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHI
DYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGN
WAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA
VQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGG
CSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSN
SQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWM
AFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAE
EKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASE
KDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHD
GYLPSNIDDLPSHEAPLADSLEELEPQHISLSVFPSSSLHPLTFSCGDKLTLDQLKMR
CDSLML"
BASE COUNT 1073 a 1054 c 976 g 937 t
ORIGIN
1 tgcagagaac agagaaagga catctgcgag gaaagttccc tgatggctgt caacaaagtg
61 ccacgtctct atggctgtgt acgctgagca cacgatttta tcgcgcctat catatcttgg
121 tgcataaacg cacctcacct cggtcaaccc ttgctccgtc ttatgagaca ggctttatta
181 tccgcatttt atatgagggg aatctgacgg tggagagaga attatcttgc tcaaggcgac
241 acagcagagc ccacaggtgg cagaatccca cccgagcccg cttcgacccg cggggtggaa
301 accacgggcg cccgcccggc tgcgcttcca gagctgaact gagaagcgag tcctctccgc
361 cctgcggcca ccgcccagcc ccgacccccg ccccggcccg atcctcactc gccgccagct
421 ccccgcgccc accccggagt tggtggcgca gaggcgggag gcggaggcgg gagggcgggc
481 gctggcaccg ggaacgcccg agcgccggca gagagcgcgg agagcgcgac acgtgcggcc
541 cagagcaccg gggccacccg gtccccgcag gcccgggacc gcgcccgctg gcaggcgaca
601 cgtggaagaa tacggagttc tataccagag ttgattgttg atggcacata cttttagagg
661 atgctcattg gcatttatgt ttataatcac gtggctgttg attaaagcaa aaatagatgc
721 gtgcaagaga ggcgatgtga ctgtgaagcc ttcccatgta attttacttg gatccactgt
781 caatattaca tgctctttga agcccagaca aggctgcttt cactattcca gacgtaacaa
841 gttaatcctg tacaagtttg acagaagaat caattttcac catggccact ccctcaattc
901 tcaagtcaca ggtcttcccc ttggtacaac cttgtttgtc tgcaaactgg cctgtatcaa
961 tagtgatgaa attcaaatat gtggagcaga gatcttcgtt ggtgttgctc cagaacagcc
1021 tcaaaattta tcctgcatac agaagggaga acaggggact gtggcctgca cctgggaaag
1081 aggacgagac acccacttat acactgagta tactctacag ctaagtggac caaaaaattt
1141 aacctggcag aagcaatgta aagacattta ttgtgactat ttggactttg gaatcaacct
1201 cacccctgaa tcacctgaat ccaatttcac agccaaggtt actgctgtca atagtcttgg
1261 aagctcctct tcacttccat ccacattcac attcttggac atagtgaggc ctcttcctcc
1321 gtgggacatt agaatcaaat ttcaaaaggc ttccgtgagc agatgtaccc tttattggag
1381 agatgaggga ctggtactgc ttaatcgact cagatatcgg cccagtaaca gcaggctctg
1441 gaatatggtt aatgttacaa aggccaaagg aagacatgat ttgctggatc tgaaaccatt
1501 tacagaatat gaatttcaga tttcctctaa gctacatctt tataagggaa gttggagtga
1561 ttggagtgaa tcattgagag cacaaacacc agaagaagag cctactggga tgttagatgt
1621 ctggtacatg aaacggcaca ttgactacag tagacaacag atttctcttt tctggaagaa
1681 tctgagtgtc tcagaggcaa gaggaaaaat tctccactat caggtgacct tgcaggagct
1741 gacaggaggg aaagccatga cacagaacat cacaggacac acctcctgga ccacagtcat
1801 tcctagaacc ggaaattggg ctgtggctgt gtctgcagca aattcaaaag gcagttctct
1861 gcccactcgt attaacataa tgaacctgtg tgaggcaggg ttgctggctc ctcgccaggt
1921 ctctgcaaac tcagagggca tggacaacat tctggtgact tggcagcctc ccaggaaaga
1981 tccctctgct gttcaggagt acgtggtgga atggagagag ctccatccag ggggtgacac
2041 acaggtccct ctaaactggc tacggagtcg accctacaat gtgtctgctc tgatttcaga
2101 gaacataaaa tcctacatct gttatgaaat ccgtgtgtat gcactctcag gggatcaagg
2161 aggatgcagc tccatcctgg gtaactctaa gcacaaagca ccactgagtg gcccccacat
2221 taatgccatc acagaggaaa aggggagcat tttaatttca tggaacagca ttccagtcca
2281 ggagcaaatg ggctgcctcc tccattatag gatatactgg aaggaacggg actccaactc
2341 ccagcctcag ctctgtgaaa ttccctacag agtctcccaa aattcacatc caataaacag
2401 cctgcagccc cgagtgacat atgtcctgtg gatgacagct ctgacagctg ctggtgaaag
2461 ttcccacgga aatgagaggg aattttgtct gcaaggtaaa gccaattgga tggcgtttgt
2521 ggcaccaagc atttgcattg ctatcatcat ggtgggcatt ttctcaacgc attacttcca
2581 gcaaaaggtg tttgttctcc tagcagccct cagacctcag tggtgtagca gagaaattcc
2641 agatccagca aatagcactt gcgctaagaa atatcccatt gcagaggaga agacacagct
2701 gcccttggac aggctcctga tagactggcc cacgcctgaa gatcctgaac cgctggtcat
2761 cagtgaagtc cttcatcaag tgaccccagt tttcagacat cccccctgct ccaactggcc
2821 acaaagggaa aaaggaatcc aaggtcatca ggcctctgag aaagacatga tgcacagtgc
2881 ctcaagccca ccacctccaa gagctctcca agctgagagc agacaactgg tggatctgta
2941 caaggtgctg gagagcaggg gctccgaccc aaagccagaa aacccagcct gtccctggac
3001 ggtgctccca gcaggtgacc ttcccaccca tgatggctac ttaccctcca acatagatga
3061 cctcccctca catgaggcac ctctcgctga ctctctggaa gaactggagc ctcagcacat
3121 ctccctttct gttttcccct caagttctct tcacccactc accttctcct gtggtgataa
3181 gctgactctg gatcagttaa agatgaggtg tgactccctc atgctctgag tggtgaggct
3241 tcaagcctta aagtcagtgt gccctcaacc agcacagcct gccccaattc ccccagcccc
3301 tgctccagca gctgtcatct ctgggtgcca ccatcggtct ggctgcagct agaggacagg
3361 caagccagct ctgggggagt cttaggaact gggagttggt cttcactcag atgcctcatc
3421 ttgcctttcc cagggcctta aaattacatc cttcactgtg tggacctaga gactccaact
3481 tgaattccta gtaactttct tggtatgctg gccagaaagg gaaatgagga ggagagtaga
3541 aaccacagct cttagtagta atggcataca gtctagagga ccattcatgc aatgactatt
3601 tctaaagcac ctgctacaca gcaggctgta cacagcagat cagtactgtt caacagaact
3661 tcctgagatg atggaaatgt tctacctctg cactcactgt ccagtacatt agacactagg
3721 cacattggct gttaatcact tggaatgtgt ttagcttgac tgaggaatta aattttgatt
3781 gtaaatttaa atcgccacac atggctagtg gctactgtat tggagtgcac agctctagat
3841 ggctcctaga ttattgagag cctccaaaac aaatcaacct agttctatag atgaagacat
3901 aaaagacact ggtaaacacc aatgtaaaag ggcccccaag gtggtcatga ctggtctcat
3961 ttgcagaagt ctaagaatgt acctttttct ggccgggcgt ggtagctcat gcctgtaatc
4021 ccagcacttt gggaggctga
//