LOCUS HSU63289 2113 bp mRNA linear HUM 12-DEC-1996
DEFINITION Human RNA-binding protein CUG-BP/hNab50 (NAB50) mRNA, complete cds.
ACCESSION U63289
VERSION U63289.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2113)
AUTHORS Timchenko,L.T., Miller,J.W., Timchenko,N.A., DeVore,D.R.,
Datar,K.V., Lin,L., Roberts,R., Caskey,C.T. and Swanson,M.S.
TITLE Identification of a (CUG)n triplet repeat RNA-binding protein and
its expression in myotonic dystrophy
JOURNAL Nucleic Acids Res. 24 (22), 4407-4414 (1996)
PUBMED 8948631
REFERENCE 2 (bases 1 to 2113)
AUTHORS Timchenko,L.T., Miller,J.W., Timchenko,N.A., DeVore,D.R.,
Datar,K.V., Lin,L., Roberts,R., Caskey,C.T. and Swanson,M.S.
TITLE Direct Submission
JOURNAL Submitted (08-JUL-1996) Molecular Genetics and Microbiology,
University of Florida, 1600 SW Archer Road, Gainesville, FL
32610-0266, USA
FEATURES Location/Qualifiers
source 1..2113
/db_xref="H-InvDB:HIT000220763"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="osteosarcoma cell line"
gene 1..2113
/gene="NAB50"
CDS 138..1586
/gene="NAB50"
/function="binds to (CUG)n triplet repeats"
/note="RNA-binding protein"
/codon_start=1
/product="CUG-BP/hNab50"
/protein_id="AAC50895.1"
/translation="MNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYE
INVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKN
NAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAM
AQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLA
GLNTLGPQYLALLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSG
TNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAA
LNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKE
GPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVS
AQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY"
BASE COUNT 523 a 518 c 523 g 549 t
ORIGIN
1 gggcagcggc agcggcggcg ggacgcggag gctcccccgg gattcggcct cagcagcgag
61 gcggcggcgg cggctgcgga ggcgcaggca gcaactgagg cagcggcagg ctcaggtgca
121 gccgctgctc aaagaaaatg aacggcaccc tggaccaccc agaccaacca gatcttgatg
181 ctatcaagat gtttgtgggc caggttccaa ggacctggtc tgaaaaggac ttgcgggaac
241 tcttcgaaca gtatggtgct gtgtatgaaa tcaacgtcct aagggatagg agccaaaacc
301 cgcctcagag caaagggtgc tgttttgtta cattttacac ccgtaaagct gcattagaag
361 ctcagaatgc tcttcacaac atgaaagtcc tcccagggat gcatcaccct atacagatga
421 aacctgctga cagtgagaag aacaatgcag tggaagacag gaagctgttt attggtatga
481 tttccaagaa gtgcactgaa aatgacatcc gagtcatgtt ctcttcgttt ggacagattg
541 aagaatgccg gatattgcgg ggacctgatg gcctgagccg aggttgtgca tttgtgactt
601 ttacaacaag agccatggca cagacggcta tcaaggcaat gcaccaagca cagaccatgg
661 agggttgctc atcacccatg gtggtaaaat ttgctgatac acagaaggac aaagaacaga
721 agagaatggc ccagcagctc cagcagcaga tgcagcaaat cagcgcagca tctgtgtggg
781 gaaaccttgc tggtctaaat actcttggac cccagtattt agcactcctt cagcagactg
841 cctcctctgg gaacctcaac accctgagca gcctccaccc aatgggaggg ttgaatgcaa
901 tgcagttaca gaatttggct gcactagctg ctgcagctag tgcagctcag aacacaccaa
961 gtggtaccaa tgctctcact acatccagca gtcccctcag cgtgctcact agttcagggt
1021 cctcacctag ctctagcagc agtaattctg tcaaccccat agcctcactt ggagccctgc
1081 agacattagc tggagcaacg gctggcctca atgttggctc tttggcagga atggctgctt
1141 taaatggtgg cctgggcagc agtggccttt ccaatggcac cgggagcacc atggaggccc
1201 tcactcaggc ctactcgggt atccagcaat atgctgctgc tgcgctcccc actctgtaca
1261 accagaatct tctgacacag cagagtattg gtgctgctgg aagccagaag gaaggtccag
1321 agggagccaa cctgttcatc taccacctgc cccaggagtt tggtgatcag gacctgctgc
1381 agatgtttat gccctttggg aatgtcgtgt ctgccaaggt tttcatagac aagcagacaa
1441 acctgagcaa gtgttttggt tttgtaagtt acgacaatcc tgtttcggcc caagctgcca
1501 tccagtccat gaacggcttt cagattggca tgaagcggct taaagtgcag ctcaaacgtt
1561 cgaagaatga cagcaagccc tactgagcgt gctcccctct gagactggag tgagagggtc
1621 ttctgattcc tgccgtttgt tcatcgttgt gcctaaagca tgtcgatgtg gcgtcaagta
1681 catcgtccaa atccctgtct cttcagcttc tctgatgctt gaactctcac ctttgacctt
1741 gtgttgacct ttgatgctga tgtgtatttt tattatgttt gtttctttct tcgttttttt
1801 ttcttttttt ctttcctttt tttttccttt tgtgctgcca aattggtttt gctagaacga
1861 ctgctgaagg ggaaatattt aaacttgcat ttgaatataa aaaaaatcta tttttctaga
1921 acttcataag ataaccactt gattttgtga ttccaattct ttgtaattgt cttcagagca
1981 gccctactag cacataccgc gtggtgtttg tatttctgtg aacacacagc cagtccgttt
2041 ctaggctttg tttctctgtg tgcttagttt taaagacaac tttgaagtaa acaatgaaat
2101 aaaagatgtc act
//