LOCUS HSU62858 1572 bp mRNA linear HUM 09-MAR-2000
DEFINITION Human interleukin-13 receptor mRNA, complete cds.
ACCESSION U62858
VERSION U62858.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1572)
AUTHORS Aman,M.J., Tayebi,N., Obiri,N.I., Puri,R.K., Modi,W.S. and
Leonard,W.J.
TITLE cDNA cloning and characterization of the human interleukin 13
receptor alpha chain
JOURNAL J. Biol. Chem. 271 (46), 29265-29270 (1996)
PUBMED 8910586
REFERENCE 2 (bases 1 to 1572)
AUTHORS Aman,M.J., Tayebi,N., Modi,W.S. and Leonard,W.J.
TITLE Direct Submission
JOURNAL Submitted (02-JUL-1996) Lab. of Molecular Immunology, NHLBI, NIH,
9000 Rockville Pike, Bethesda, MD 20892-1674, USA
FEATURES Location/Qualifiers
source 1..1572
/db_xref="H-InvDB:HIT000220743"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
CDS 85..1368
/function="cytokine receptor"
/note="IL-13 receptor; IL-13R or IL-13Ralpha; this protein
together with the 140 kDa IL-4 binding protein, IL-4R or
IL-4Ralpha, can form a functional receptor for IL-13;
IL-13R plus IL-4R is also one of the functional forms of
the IL-4 receptor, the other is IL-4R plus the common
cytokine receptor gamma chain"
/codon_start=1
/product="interleukin-13 receptor"
/protein_id="AAB37127.1"
/translation="MEWPARLCGLWALLLCAGGGGGGGGAAPTETQPPVTNLSVSVEN
LCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERICLQVGSQC
STNESEKPSILVEKCISPPEGDPESAVIELQCIWHNLSYMKCSWLPGRNTSPDTNYTL
YYWHRSLEKIHQCENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFN
IVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQNFISRCLFYEVEVNNSQTETHNVFY
VQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEM
SIGKKRNSTLYITMLLIVPVIVADAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQ
NDDTLHWKKYDIYEKQTKEETDSVVLIENLKKASQ"
BASE COUNT 477 a 332 c 358 g 405 t
ORIGIN
1 cgggtaattt tttcaaagta aacgcttcgg gccccgcggg acactcagct aagagcccgg
61 ccgggctccg aggcgagagg ctgcatggag tggccggcgc ggctctgcgg gctgtgggcg
121 ctgctgctct gcgccggcgg cgggggcggg ggcgggggcg ccgcgcctac ggaaactcag
181 ccacctgtga caaatttgag tgtctctgtt gaaaacctct gcacagtaat atggacatgg
241 aatccacccg agggagccag ctcaaattgt agtctatggt attttagtca ttttggcgac
301 aaacaagata agaaaatagc tccggaaact cgtcgttcaa tagaagtacc cctgaatgag
361 aggatttgtc tgcaagtggg gtcccagtgt agcaccaatg agagtgagaa gcctagcatt
421 ttggttgaaa aatgcatctc acccccagaa ggtgatcctg agtctgctgt gattgagctt
481 caatgcattt ggcacaacct gagctacatg aagtgttctt ggctccctgg aaggaatacc
541 agtcccgaca ctaactatac tctctactat tggcacagaa gcctggaaaa aattcatcaa
601 tgtgaaaaca tctttagaga aggccaatac tttggttgtt cctttgatct gaccaaagtg
661 aaggattcca gttttgaaca acacagtgtc caaataatgg tcaaggataa tgcaggaaaa
721 attaaaccat ccttcaatat agtgccttta acttcccgtg tgaaacctga tcctccacat
781 attaaaaacc tctccttcca caatgatgac ctatatgtgc aatgggagaa tccacagaat
841 tttattagca gatgcctatt ttatgaagta gaagtcaata acagccaaac tgagacacat
901 aatgttttct acgtccaaga ggctaaatgt gagaatccag aatttgagag aaatgtggag
961 aatacatctt gtttcatggt ccctggtgtt cttcctgata ctttgaacac agtcagaata
1021 agagtcaaaa caaataagtt atgctatgag gatgacaaac tctggagtaa ttggagccaa
1081 gaaatgagta taggtaagaa gcgcaattcc acactctaca taaccatgtt actcattgtt
1141 ccagtcatcg tcgcagatgc aatcatagta ctcctgcttt acctaaaaag gctcaagatt
1201 attatattcc ctccaattcc tgatcctggc aagattttta aagaaatgtt tggagaccag
1261 aatgatgata ctctgcactg gaagaagtac gacatctatg agaagcaaac caaggaggaa
1321 accgactctg tagtgctgat agaaaacctg aagaaagcct ctcagtgatg gagataattt
1381 atttttacct tcactgtgac cttgagaaga ttcttcccat tctccatttg ttatctggga
1441 acttattaga tggaaactga aactactgca ccatttaaaa acaggcagct cataagagcc
1501 acaggtcttt atgttgagtc gctagcaaga acaagaaaag ttttaaagaa agatgttgct
1561 tactatgagt gg
//