LOCUS HSU62583 2995 bp mRNA linear HUM 05-FEB-1997
DEFINITION Human Prt1 homolog mRNA, complete cds.
ACCESSION U62583
VERSION U62583.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2995)
AUTHORS Methot,N., Rom,E., Olsen,H. and Sonenberg,N.
TITLE The human homologue of the yeast Prt1 protein is an integral part
of the eukaryotic initiation factor 3 complex and interacts with
p170
JOURNAL J. Biol. Chem. 272 (2), 1110-1116 (1997)
PUBMED 8995410
REFERENCE 2 (bases 1 to 2995)
AUTHORS Methot,N., Rom,E., Olsen,H. and Sonenberg,N.
TITLE Direct Submission
JOURNAL Submitted (28-JUN-1996) Biochemistry, McGill University, 3655
Drummond St. Rm 807, Montreal, QUE H3G 1Y6, Canada
FEATURES Location/Qualifiers
source 1..2995
/db_xref="H-InvDB:HIT000220728"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
/clone_lib="cDNA library provided by Dr. Morag Park"
CDS 54..2675
/function="interacts with the large subunit of eIF3, p170"
/note="similar to yeast Prt1; contains an RNA recognition
motif; eukaryotic initiation factor 3 subunit"
/codon_start=1
/product="Prt1 homolog"
/protein_id="AAB42010.1"
/translation="MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPE
AAGTEASSEEVGIAEAGPEPEVRTEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVP
AQGEAPGEQARDAGSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFV
DDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIT
NDFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTIS
DEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERAR
WTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQRFSHQGVQLIDFSPCERYLVTFS
PLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYE
TPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRN
LFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKETII
AFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIFWSPQGQFVV
LAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYW
LWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQS
KASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEET
IEFFVTEEIIPLGIRSDLEHCAQPCVLWSRGRPAGSRVTPASSLCSLALDCDCAWILP
LRHIFVPFSPWCLQWGI"
BASE COUNT 717 a 770 c 910 g 598 t
ORIGIN
1 tgctaccgaa ggccggcggc cgcggagccc tgcgagtagg cagcgttggg cccatgcagg
61 acgcggagaa cgtggcggtg cccgaggcgg ccgaggagcg cgccgagccc ggccagcagc
121 agccggccgc cgagccgccg ccagccgagg ggctgctgcg gcccgcgggg cccggcgctc
181 cggaggccgc ggggaccgag gcctccagtg aggaggtggg gatcgcggag gccgggccgg
241 agcccgaggt gaggaccgag ccggcggccg aggcagaggc ggcctccggc ccgtccgagt
301 cgccctcgcc gccggccgcc gaggagctgc ccgggtcgca tgctgagccc cctgtcccgg
361 cacagggcga ggccccagga gagcaggctc gggacgcagg ctccgacagc cgggcccagg
421 cggtgtccga ggacgcggga ggaaacgagg gcagagcggc cgaggccgaa ccccgggcgc
481 tggagaacgg cgacgcggac gagccctcct tcagcgaccc cgaggacttc gtggacgacg
541 tgagcgagga agaattactg ggagatgtac tcaaagatcg gccccaggaa gcagatggaa
601 tcgattcggt gattgtagtg gacaatgtcc ctcaggtggg acccgaccga cttgagaaac
661 tcaaaaatgt catccacaag atcttttcca agtttgggaa aatcacaaat gatttttatc
721 ctgaagagga tgggaagaca aaagggtata ttttcctgga gtacgcgtcc cctgcccacg
781 ctgtggatgc tgtgaagaac gccgacggct acaagcttga caagcagcac acattccggg
841 tcaacctctt tacggatttt gacaagtata tgacgatcag tgacgagtgg gatattccag
901 agaaacagcc tttcaaagac ctggggaact tacgttactg gcttgaagag gcagaatgca
961 gagatcagta cagtgtgatt tttgagagtg gagaccgcac ttccatattc tggaatgacg
1021 taaaagaccc tgtctcaatt gaagaaagag cgagatggac agagacgtat gtgcgttggt
1081 ctcctaaggg cacctacctg gctacctttc atcaaagagg cattgctcta tgggggggag
1141 agaaattcaa gcaaattcag agattcagcc accaaggggt tcagcttatt gacttctcac
1201 cttgtgaaag gtacctggtg acctttagcc ccctgatgga cacgcaggat gaccctcagg
1261 ccataatcat ctgggacatc cttacggggc acaagaagag gggttttcac tgtgagagct
1321 cagcccattg gcctattttt aagtggagcc atgatggcaa attctttgcc agaatgaccc
1381 tggatacgct tagcatctat gaaactcctt ctatgggtct tttggacaag aagagtttga
1441 agatctctgg gataaaagac ttttcttggt ctcctggtgg taacataatc gccttctggg
1501 tgcctgaaga caaagatatt ccagccaggg taaccctgat gcagctccct accaggcaag
1561 agatccgagt gaggaacctg ttcaatgtgg tggactgcaa gctccattgg cagaagaacg
1621 gagactactt gtgtgtgaaa gtagatagga ctccgaaagg cacccagggt gttgtcacaa
1681 attttgaaat tttccgaatg agggagaaac aggtacctgt ggatgtggtc gagatgaaag
1741 aaaccatcat agcctttgcc tgggaaccaa atggaagtaa gtttgctgtg ctgcacggag
1801 aggctccgcg gatatctgtg tctttctacc acgtcaaaaa caacgggaag attgaactca
1861 tcaagatgtt cgacaagcag caggcgaaca ccatcttctg gagcccccaa ggacagttcg
1921 tggtgttggc gggcctgagg agtatgaacg gtgccttagc gtttgtggac acttcggact
1981 gcacggtcat gaacatcgca gagcactaca tggcttccga cgtcgaatgg gatcctactg
2041 ggcgctacgt cgtcacctct gtgtcctggt ggagccataa ggtggacaac gcgtactggc
2101 tgtggacttt ccagggacgc ctcctgcaga agaacaacaa ggaccgcttc tgccagctgc
2161 tgtggcggcc ccggcctccc acactcctga gccaggaaca gatcaagcaa attaaaaagg
2221 atctgaagaa atactctaag atctttgaac agaaggatcg tttgagtcag tccaaagcct
2281 caaaggaatt ggtggagaga aggcgcacca tgatggaaga tttccggaag taccggaaaa
2341 tggcccagga gctctatatg gagcagaaaa acgagcgcct ggagttgcga ggaggggtgg
2401 acactgacga gctggacagc aacgtggacg actgggaaga ggagaccatt gagttcttcg
2461 tcactgaaga aatcattccc ctcggaatca ggagtgacct ggagcactgt gcgcagccgt
2521 gtgtgctgtg gagccgaggc cgtcctgcag gaagccgcgt gactcccgcc tcctccctgt
2581 gctctctggc tctggactgt gactgcgcct ggattctgcc attgcgacac atttttgtgc
2641 ctttcagccc ctggtgtctg cagtggggga tttaaggcac ccgcttccac ttctttcttg
2701 tttggagttt tctgttggaa ccgccggcgt tggctccgaa gacttagcga cgcactggcg
2761 gcaccttctc ctgcgcccag tgatgtttcc acggtgcctg tacacagccg agcagcattt
2821 ccgttgaagg acttgcatcc ccattgcggg cagtgctgga cgtgtcccgg agacccaccg
2881 gagggcgccg catgccttgt acccccaccg tgcaggttgt ggccggtttt ctccgcaggt
2941 tgaacatgga aataaaagca aacttgtatg aaaaaaaaaa aaaaaaaaac tcgag
//