LOCUS HSU62434 1828 bp mRNA linear HUM 11-JAN-1997
DEFINITION Human nicotinic acetylcholine receptor alpha5 subunit precursor,
mRNA, complete cds.
ACCESSION U62434
VERSION U62434.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1828)
AUTHORS Elliott,K.J., Ellis,S.B., Berckhan,K.J., Urrutia,A.,
Chavez-Noriega,L.E., Johnson,E.C., Velicelebi,G. and Harpold,M.M.
TITLE Comparative structure of human neuronal alpha 2-alpha 7 and beta
2-beta 4 nicotinic acetylcholine receptor subunits and functional
expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and
beta 4 subunits
JOURNAL J. Mol. Neurosci. 7 (3), 217-228 (1996)
PUBMED 8906617
REFERENCE 2 (bases 1 to 1828)
AUTHORS Elliott,K.J.
TITLE Direct Submission
JOURNAL Submitted (28-JUN-1996) Kathryn J. Elliott, SIBIA Neurosciences,
Inc., 505 Coast Blvd. So., La Jolla, CA 92037, USA
FEATURES Location/Qualifiers
source 1..1828
/db_xref="H-InvDB:HIT000220718"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="KEalpha5.5"
/cell_line="IMR32"
/cell_type="neuroblastoma"
/clone_lib="SIBIA lambda gt11 library #3 (M. Williams)"
5'UTR 1..154
CDS 155..1561
/codon_start=1
/product="nicotinic acetylcholine receptor alpha5 subunit
precursor"
/protein_id="AAB40112.1"
/translation="MAARGSGPRALRLLLLVQLVAGRCGLAGAAGGAQRGLSEPSSIA
KHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQE
WIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTW
TPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEW
EIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPS
NEGEKICLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFA
INIHHRSSSTHNAMAPLVRKIFLHTLPKLLCMRSHVDRYFTQKEETESGSGPKSSRNT
LEAALNSIRYITRHIMKENDVREVVEDWKFIAQVLDRMFLWTFLFVSIVGSLGLFVPV
IYKWANILIPVHIGNANK"
sig_peptide 155..220
mat_peptide 221..1558
/product="nicotinic acetylcholine receptor alpha5 subunit"
3'UTR 1562..1828
BASE COUNT 496 a 372 c 419 g 541 t
ORIGIN
1 cccggcggga gctgtggcgc ggagcggccc cgctgctgcg tctgccctcg ttttgtctca
61 cgactcacac tcagtgctgc attccccaag agttcgcgtt ccccgcgcgg cggtcgagag
121 gcggctgccc gcggtcccgc gcgggcgcgg ggcgatggcg gcgcgggggt cagggccccg
181 cgcgctccgc ctgctgctct tggtccagct ggtcgcgggg cgctgcggtc tagcgggcgc
241 ggcgggcggc gcgcagagag gattatctga accttcttct attgcaaaac atgaagatag
301 tttgcttaag gatttatttc aagactacga aagatgggtt cgtcctgtgg aacacctgaa
361 tgacaaaata aaaataaaat ttggacttgc aatatctcaa ttggtggatg tggatgagaa
421 aaatcagtta atgacaacaa acgtctggtt gaaacaggaa tggatagatg taaaattaag
481 atggaaccct gatgactatg gtggaataaa agttatacgt gttccttcag actctgtctg
541 gacaccagac atcgttttgt ttgataatgc agatggacgt tttgaaggga ccagtacgaa
601 aacagtcatc aggtacaatg gcactgtcac ctggactcca ccggcaaact acaaaagttc
661 ctgtaccata gatgtcacgt ttttcccatt tgaccttcag aactgttcca tgaaatttgg
721 ttcttggact tatgatggat cacaggttga tataattcta gaggaccaag atgtagacaa
781 gagagatttt tttgataatg gagaatggga gattgtgagt gcaacaggga gcaaaggaaa
841 cagaaccgac agctgttgct ggtatccgta tgtcacttac tcatttgtaa tcaagcgcct
901 gcctctcttt tataccttgt tccttataat accctgtatt gggctctcat ttttaactgt
961 acttgtcttc tatcttcctt caaatgaagg tgaaaagatt tgtctctgca cttcagtact
1021 tgtgtctttg actgtcttcc ttctggttat tgaagagatc ataccatcat cttcaaaagt
1081 catacctcta attggagagt atctggtatt taccatgatt tttgtgacac tgtcaattat
1141 ggtaaccgtc ttcgctatca acattcatca tcgttcttcc tcaacacata atgccatggc
1201 gcctttggtc cgcaagatat ttcttcacac gcttcccaaa ctgctttgca tgagaagtca
1261 tgtagacagg tacttcactc agaaagagga aactgagagt ggtagtggac caaaatcttc
1321 tagaaacaca ttggaagctg cgctcaattc tattcgctac attacaagac acatcatgaa
1381 ggaaaatgat gtccgtgagg ttgttgaaga ttggaaattc atagcccagg ttcttgatcg
1441 gatgtttctg tggacttttc ttttcgtttc aattgttgga tctcttgggc tttttgttcc
1501 tgttatttat aaatgggcaa atatattaat accagttcat attggaaatg caaataagtg
1561 aagcctccca agggactgaa gtatacattt agttaacaca catatatctg atggcaccta
1621 taaaattatg aaaatgtaag ttatgtgtta aatttagtgc aagctttaac agactaagtt
1681 gctaacctca atttatgtta acagatgatc catttgaaca gttggctgta tgactgaagt
1741 aataactgat gagatacatt tgatcttgta aaaatagcaa aatattatct gaactggact
1801 agtgaaaaat ctagtatttg tatcctgg
//