LOCUS HSU61843 3035 bp mRNA linear HUM 22-OCT-2007
DEFINITION Homo sapiens discs large protein P-dlg mRNA, complete cds.
ACCESSION U61843
VERSION U61843.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3035)
AUTHORS Nakamura,H., Sudo,T., Tsuiki,H., Miyake,H., Morisaki,T., Sasaki,J.,
Masuko,N., Kochi,M., Ushio,Y. and Saya,H.
TITLE Identification of a novel human homolog of the Drosophila dlg,
P-dlg, specifically expressed in the gland tissues and interacting
with p55
JOURNAL FEBS Lett. 433 (1-2), 63-67 (1998)
PUBMED 9738934
REFERENCE 2 (bases 1 to 3035)
AUTHORS Nakamura,H., Makino,K., Nakao,M., Ushio,Y. and Saya,H.
TITLE Direct Submission
JOURNAL Submitted (24-JUN-1996) Tumor Genetics and Biology, Kumamoto
University School of Medicine, Honjo 2-2-1, Kumamoto 860, Japan
FEATURES Location/Qualifiers
source 1..3035
/db_xref="H-InvDB:HIT000220703"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
/dev_stage="fetal"
CDS 364..2388
/note="similar to Drosophila discs large protein"
/codon_start=1
/product="discs large protein P-dlg"
/protein_id="AAC61295.1"
/translation="MRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGS
ERGSVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVNPASLGERRKDRPYVEE
PRHVKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSA
TEQQARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHSTLQGSGTTTPEH
PSVIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGNL
HGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQ
YRPEEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTLPQGTFGSWMAW
QLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKH
KRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVK
EMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIXEITE
KNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQ
FEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL"
repeat_region 604..915
/note="dlg homology repeat 1; DHR1"
repeat_region 1027..1359
/note="dlg homology repeat 2; DHR2"
misc_feature 1411..1623
/note="encodes SH3 domain"
misc_feature 1756..2380
/note="encodes guanylate kinase-related domain"
BASE COUNT 681 a 891 c 857 g 602 t
ORIGIN
1 tagcagacac tcttgccctt gcatctgcag gaacagaagt gtgtcccggc cagtggagaa
61 ctctccccgg agctccagga gtgggcacct tactcgcctg ggcattccag ccggcacagc
121 aaccccccgc tataccctag caggccgtct gtgggcactg ttccccggag tttgaccccc
181 agcaccactg tgagctccat cctgcggaac cccatctaca ctgtgcgcag tcacagggtc
241 ggcccctgca gctctccacc tgcggcccga gatgctggcc cccagggttt gcatcccagt
301 gtccagcacc agggacgcct gagcctggac ctgagccaca ggacctgcag cgactactcc
361 gagatgagag ccacccatgg gtccaactca ctgccctcca gcgcccgcct gggttcttcg
421 agtaacttgc agttcaaggc ggaacgcatt aaaatcccat caacaccaag atatccgcgg
481 agtgtcgtgg gctccgagag aggttcagtg tcacattctg aatgcagcac tcctccacag
541 tcacccctga acatcgacac cctgtcctct tgtagccagt cccagacctc agcctccaca
601 ttgcccagaa tcgctgtcaa ccccgcgtcc ctcggggagc ggagaaagga caggccttat
661 gtggaggagc cacgccacgt gaaggtgcag aagggctcag agccgctggg catctccatc
721 gtgagtggag agaagggcgg catctacgtc tccaaggtga ccgtggggag catcgctcac
781 caggctggcc tcgagtatgg ggatcagtta ctggagttca acggcataaa cctgcggagc
841 gccacggagc agcaggcgcg gctcatcatc gggcagcagt gtgataccat caccatcctg
901 gcccagtaca acccccacgt gcaccagctc agcagccact cccggtccag ctcacacctg
961 gaccctgccg gtacccactc cactctccag ggcagtggca ccaccacccc ggagcatcca
1021 tctgtcatcg acccactgat ggagcaggac gaggggccta gcaccccccc agccaagcag
1081 agcagctcca ggattgcggg agatgccaac aagaagaccc tggagccacg cgttgtcttc
1141 atcaaaaagt cccagctgga gcttggggtg cacttgtgtg gtgggaacct gcatggggtg
1201 tttgtggccg aggtggagga tgacagtcct gccaagggtc ctgacggcct cgtgccaggg
1261 gacctcatcc tggagtatgg cagcctggac gtgcggaaca agacagtgga ggaagtctat
1321 gtggagatgc tgaagcccag ggatggcgtc cgcctgaagg tgcagtaccg ccctgaggag
1381 ttcacgaagg ccaagggcct gcctggtgac agcttctaca tcagggccct gtacgaccgg
1441 ctggcagatg tggagcaaga gttgagcttt aagaaggacg acatcctcta cgtggatgac
1501 accttacccc agggcacgtt cgggtcctgg atggcttggc agctggacga gaatgcccag
1561 aagatccagc gcgggcagat tcccagcaaa tatgtgatgg accaagaatt ctccaggagg
1621 ctcagcatgt ctgaagtcaa agatgacaat agcgccacaa agacgctgtc agcggctgca
1681 cgccggtcct tttttcggag gaaacacaag cacaaacgca gcgggtccaa ggacgggaaa
1741 gacctgctcg ccttggatgc cttttccagt gactccattc cactctttga agattcggtg
1801 agcctggcct atcagcgggt ccagaaggtg gactgcaccg ctctgaggcc tgtcctgatt
1861 ctggggcctt tgctggacgt ggtgaaggag atgctggtga atgaggctcc tggcaagttc
1921 tgcagatgtc cccttgaggt gatgaaggcc tcccagcagg ccattgagcg gggtgtcaaa
1981 gattgcctgt ttgtcgacta taagcggaga agcggccatt tcgatgtgac cactgtggcg
2041 tcaatawagg agatcacaga aaagaaccga cactgcctcc tggacattgc tccgcacgct
2101 attgagcggc tccaccacat gcacatctac cccattgtca tcttcatcca ctacaagagc
2161 gccaagcaca tcaaggagca gagagacccc atctacctga gggacaaggt gactcagagg
2221 cattccaaag agcartttga ggcggcgcag aagcttgagc aggagtacag caggtacttc
2281 acaggggtca tccagggagg agccctgtca agcatttgca ctcagatctt ggcaatggtc
2341 aatcaagaac aaaataaagt cctgtggatt ccagcctgcc cgctctagga gaatgctgtg
2401 ctgtggatga ctgcagctgg ccgcctgagg ggacaccaga ctcagctctt ttctagcgac
2461 tgaaagtaga agtctgtccg tctatgaaca tgcgggggaa ggatccggaa ccaggaccca
2521 gaagcacctc ctttgtagac agagggccac ggctgcgtgc gatccaggcc caggmccaca
2581 cactctgccc gtgtcacacg tgtgctttaa cacaaaacag ataacactaa agacgggttc
2641 agcacccacc tttctttagc cagctgatca gagatgctgc aaagagaacc tttcggatca
2701 ctcgtttaca agccttttct aagtatttgg tggtttatgt ttacttgaac ggctccatgt
2761 tgccggtgcc cagcccctgt cccctctgtc aaccccctgt cgctttggtg ttggtttcgt
2821 tcccgtcttc agcaaaacga ccttggaacc tcaatggggg ctgctttgct ttgggaggtt
2881 cttgttggtg ggaccagagc tttgacaaac ctcctgctcc ttggtgggca cctctcctgg
2941 gaaggacgtt cacaactcca gggtgcttca gaatgcctgt ggaacmagga accagtggcc
3001 tttggatttt ttcctcccac aatgggggaa ggtga
//