LOCUS HSU60805 4171 bp mRNA linear HUM 23-JAN-1997
DEFINITION Human oncostatin-M specific receptor beta subunit (OSMRB) mRNA,
complete cds.
ACCESSION U60805
VERSION U60805.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4171)
AUTHORS Mosley,B., De Imus,C., Friend,D., Boiani,N., Thoma,B., Park,L.S.
and Cosman,D.
TITLE Dual oncostatin M (OSM) receptors. Cloning and characterization of
an alternative signaling subunit conferring OSM-specific receptor
activation
JOURNAL J. Biol. Chem. 271 (51), 32635-32643 (1996)
PUBMED 8999038
REFERENCE 2 (bases 1 to 4171)
AUTHORS Mosley,B. and Cosman,D.
TITLE Direct Submission
JOURNAL Submitted (13-JUN-1996) Bruce Mosley, Molecular Biology, Immunex
Corporation, 51 University St., Seattle, WA 98101, USA
FEATURES Location/Qualifiers
source 1..4171
/db_xref="H-InvDB:HIT000220647"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..4171
/gene="OSMRB"
CDS 368..3307
/gene="OSMRB"
/codon_start=1
/product="oncostatin-M specific receptor beta subunit"
/protein_id="AAC50946.1"
/translation="MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNST
RQSLHLQWTVHNLPYHQELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLHWSWESE
LPLECATHFVRIKSLVDDAKFPEPNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEE
GTNVTICYVSRNIQNNVSCYLEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEAS
QGNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYT
LFESFSGEKKLCTHKNWCNWQITQDSQETYNFTLIAENYLRKRSVNILFNLTHRVYLM
NPFSVNFENVNATNAIMTWKVHSIRNNFTYLCQIELHGEGKMMQYNVSIKVNGEYFLS
ELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHTVT
LFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIA
NNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQ
DVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELA
PSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSD
GSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSM
LIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKSSILSLIKFKENPHLIIMN
VSDCIPDAIEVVSKPEGTKIQFLGTRKSLTETELTKPNYLYLLPTEKNHSGPGPCICF
ENLTYNQAASDSGSCGHVPVSPKAPSMLGLMTSPENVLKALEKNYMNSLGEIPAGETS
LNYVSQLASPMFGDKDSLPTNPVEAPHCSEYKMQMAVSLRLALPPPTENSSLSSITLL
DPGEHYC"
BASE COUNT 1169 a 1004 c 911 g 1087 t
ORIGIN
1 gggccgcctc tgcacgtccg ccccggagcc cgcacccgcg ccccacgcgc cgccgaggac
61 tcggcccggc tcgtggagcc cttcgcccgc ggcgtgagta cccccgaccc gcccgtcccc
121 gctctgctcg cgccctgccg ctgcgccgcc ctcggtggct tttccgacgg gcgagccccg
181 tgctgtgcgg gaaagaatcc gacaacttcg cagcccatcc cggctggacg cgaccgggag
241 tgcagcagcc cgttcccctc ctcggtgccg cctctgccca gcgtttgctt ggctgggcta
301 ccacctgcgc tcggacggcg ctcggagggt cctcgccccc ggcctgccta cctgaaaacc
361 agaactgatg gctctatttg cagtctttca gacaacattc ttcttaacat tgctgtcctt
421 gaggacttac cagagtgaag tcttggctga acgtttacca ttgactcctg tatcacttaa
481 agtttccacc aattctacgc gtcagagttt gcacttacaa tggactgtcc acaaccttcc
541 ttatcatcag gaattgaaaa tggtatttca gatccagatc agtaggattg aaacatccaa
601 tgtcatctgg gtggggaatt acagcaccac tgtgaagtgg aaccaggttc tgcattggag
661 ctgggaatct gagctccctt tggaatgtgc cacacacttt gtaagaataa agagtttggt
721 ggacgatgcc aagttccctg agccaaattt ctggagcaac tggagttcct gggaggaagt
781 cagtgtacaa gattctactg gacaggatat attgttcgtt ttccctaaag ataagctggt
841 ggaagaaggc accaatgtta ccatttgtta cgtttctagg aacattcaaa ataatgtatc
901 ctgttatttg gaagggaaac agattcatgg agaacaactt gatccacatg taactgcatt
961 caacttgaat agtgtgcctt tcattaggaa taaagggaca aatatctatt gtgaggcaag
1021 tcaaggaaat gtcagtgaag gcatgaaagg catcgttctt tttgtctcaa aagtacttga
1081 ggagcccaag gacttttctt gtgaaaccga ggacttcaag actttgcact gtacttggga
1141 tcctgggacg gacactgcct tggggtggtc taaacaacct tcccaaagct acactttatt
1201 tgaatcattt tctggggaaa agaaactttg tacacacaaa aactggtgta attggcaaat
1261 aactcaagac tcacaagaaa cctataactt cacactcata gctgaaaatt acttaaggaa
1321 gagaagtgtc aatatccttt ttaacctgac tcatcgagtt tatttaatga atccttttag
1381 tgtcaacttt gaaaatgtaa atgccacaaa tgccatcatg acctggaagg tgcactccat
1441 aaggaataat ttcacatatt tgtgtcagat tgaactccat ggtgaaggaa aaatgatgca
1501 atacaatgtt tccatcaagg tgaacggtga gtacttctta agtgaactgg aacctgccac
1561 agagtacatg gcgcgagtac ggtgtgctga tgccagccac ttctggaaat ggagtgaatg
1621 gagtggtcag aacttcacca cacttgaagc tgctccctca gaggcccctg atgtctggag
1681 aattgtgagc ttggagccag gaaatcatac tgtgacctta ttctggaagc cattatcaaa
1741 actgcatgcc aatggaaaga tcctgttcta taatgtagtt gtagaaaacc tagacaaacc
1801 atccagttca gagctccatt ccattccagc accagccaac agcacaaaac taatccttga
1861 caggtgttcc taccaaatct gcgtcatagc caacaacagt gtgggtgctt ctcctgcttc
1921 tgtaatagtc atctctgcag accccgaaaa caaagaggtt gaggaagaaa gaattgcagg
1981 cacagagggt ggattctctc tgtcttggaa accccaacct ggagatgtta taggctatgt
2041 tgtggactgg tgtgaccata cccaggatgt gctcggtgat ttccagtgga agaatgtagg
2101 tcccaatacc acaagcacag tcattagcac agatgctttt aggccaggag ttcgatatga
2161 cttcagaatt tatgggttat ctacaaaaag gattgcttgt ttattagaga aaaaaacagg
2221 atactctcag gaacttgctc cttcagacaa ccctcacgtg ctggtggata cattgacatc
2281 ccactccttc actctgagtt ggaaagatta ctctactgaa tctcaacctg gttttataca
2341 agggtaccat gtctatctga aatccaaggc gaggcagtgc cacccacgat ttgaaaaggc
2401 agttctttca gatggttcag aatgttgcaa atacaaaatt gacaacccgg aagaaaaggc
2461 attgattgtg gacaacctaa agccagaatc cttctatgag tttttcatca ctccattcac
2521 tagtgctggt gaaggcccca gtgctacgtt cacgaaggtc acgactccgg atgaacactc
2581 ctcgatgctg attcatatcc tactgcccat ggttttctgc gtcttgctca tcatggtcat
2641 gtgctacttg aaaagtcagt ggatcaagga gacctgttat cctgacatcc ctgaccctta
2701 caagagcagc atcctgtcat taataaaatt caaggagaac cctcacctaa taataatgaa
2761 tgtcagtgac tgtatcccag atgctattga agttgtaagc aagccagaag ggacaaagat
2821 acagttccta ggcactagga agtcactcac agaaaccgag ttgactaagc ctaactacct
2881 ttatctcctt ccaacagaaa agaatcactc tggccctggc ccctgcatct gttttgagaa
2941 cttgacctat aaccaggcag cttctgactc tggctcttgt ggccatgttc cagtatcccc
3001 aaaagcccca agtatgctgg gactaatgac ctcacctgaa aatgtactaa aggcactaga
3061 aaaaaactac atgaactccc tgggagaaat cccagctgga gaaacaagtt tgaattatgt
3121 gtcccagttg gcttcaccca tgtttggaga caaggacagt ctcccaacaa acccagtaga
3181 ggcaccacac tgttcagagt ataaaatgca aatggcagtc tccctgcgtc ttgccttgcc
3241 tcccccgacc gagaatagca gcctctcctc aattaccctt ttagatccag gtgaacacta
3301 ctgctaacca gcatgccgat ttcatacctt atgctacaca gacattaaga agagcagagc
3361 tggcaccctg tcatcaccag tggccttggt ccttaatccc agtacaattt gcaggtctgg
3421 tttatataag accactacag tctggctagg ttaaaggcca gaggctatgg aacttaacac
3481 tccccattgg agcaagcttg ccctagagac ggcaggatca tgggagcatg cttaccttct
3541 gctgtttgtt ccaggctcac ctttagaaca ggagacttga gcttgaccta aggatatgca
3601 ttaaccactc tacagactcc cactcagtac tgtacagggt ggctgtggtc ctagaagttc
3661 agtttttact gaggaaatat ttccattaac agcaattatt atattgaagg ctttaataaa
3721 ggccacagga gacattacta tagcatagat tgtcaaatgt aaatttactg agcgtgtttt
3781 ataaaaaact cacaggtgtt tgaggccaaa acagatttta gacttacctt gaacggataa
3841 gaatctatag ttcactgaca cagtaaaatt aactctgtgg gtgggggcgg ggggcatagc
3901 tctaatctaa tatataaaat gtgtgatgaa tcaacaagat ttccacaatt cttctgtcaa
3961 gcttactaca gtgaaagaat gggattggca agtaacttct gacttactgt cagttgtact
4021 tctgctccat agacatcagt attctgccat catttttgat gactacctca gaacataaaa
4081 aggaacgtat atcacataat tccagtcaca gtttttggtt cctcttttct ttcaagaact
4141 atatataaat gacctgtttt cacgcggccg c
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