LOCUS HSU59912 1793 bp mRNA linear HUM 01-NOV-1996
DEFINITION Human chromosome 4 Mad homolog Smad1 mRNA, complete cds.
ACCESSION U59912
VERSION U59912.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1793)
AUTHORS Riggins,G.J., Thiagalingam,S., Rozenblum,E., Weinstein,C.L.,
Kern,S.E., Hamilton,S.R., Willson,J.K., Markowitz,S.D.,
Kinzler,K.W. and Vogelstein,B.
TITLE Mad-related genes in the human
JOURNAL Nat. Genet. 13 (3), 347-349 (1996)
PUBMED 8673135
REFERENCE 2 (bases 1 to 1793)
AUTHORS Riggins,G.J., Thiagalingam,S., Kinzler,K.W. and Vogelstein,B.V.
TITLE Direct Submission
JOURNAL Submitted (04-JUN-1996) Oncology Center, Rm. 109, Johns Hopkins,
424 N. Bond St., Baltimore, MD 21231, USA
COMMENT On Nov 1, 1996 this sequence version replaced gi:1403714.
FEATURES Location/Qualifiers
source 1..1793
/db_xref="H-InvDB:HIT000220607"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
CDS 242..1639
/note="Mad homolog"
/codon_start=1
/product="Smad1"
/protein_id="AAC50790.1"
/translation="MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKK
KGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHE
LKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG
QNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQM
PADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVY
YELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGV
HLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLL
AQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKV
LTQMGSPHNPISSVS"
BASE COUNT 483 a 445 c 392 g 473 t
ORIGIN
1 tcactgcatg tgtattcgtg agttcgcggt tgaacaactg ttcctttact ctgctccctg
61 tctttgtgct gactgggtta cttttttaaa cactaggaat ggtaatttct actcttctgg
121 acttcaaact aagaagttaa agagacttct ctgtaaataa acaaatctct tctgctgtcc
181 ttttgcattt ggagacagct ttatttcacc atatccaagg agtataacta gtgctgtcat
241 tatgaatgtg acaagtttat tttcctttac aagtccagct gtgaagagac ttcttgggtg
301 gaaacagggc gatgaagaag aaaaatgggc agagaaagct gttgatgctt tggtgaaaaa
361 actgaagaaa aagaaaggtg ccatggagga actggaaaag gccttgagct gcccagggca
421 accgagtaac tgtgtcacca ttccccgctc tctggatggc aggctgcaag tctcccaccg
481 gaagggactg cctcatgtca tttactgccg tgtgtggcgc tggcccgatc ttcagagcca
541 ccatgaacta aaaccactgg aatgctgtga gtttcctttt ggttccaagc agaaggaggt
601 ctgcatcaat ccctaccact ataagagagt agaaagccct gtacttcctc ctgtgctggt
661 tccaagacac agcgaatata atcctcagca cagcctctta gctcagttcc gtaacttagg
721 acaaaatgag cctcacatgc cactcaacgc cacttttcca gattctttcc agcaacccaa
781 cagccacccg tttcctcact ctcccaatag cagttaccca aactctcctg ggagcagcag
841 cagcacctac cctcactctc ccaccagctc agacccagga agccctttcc agatgccagc
901 tgatacgccc ccacctgctt acctgcctcc tgaagacccc atgacccagg atggctctca
961 gccgatggac acaaacatga tggcgcctcc cctgccctca gaaatcaaca gaggagatgt
1021 tcaggcggtt gcttatgagg aaccaaaaca ctggtgctct attgtctact atgagctcaa
1081 caatcgtgtg ggtgaagcgt tccatgcctc ctccacaagt gtgttggtgg atggtttcac
1141 tgatccttcc aacaataaga accgtttctg ccttgggctg ctctccaatg ttaaccggaa
1201 ttccactatt gaaaacacca ggcggcatat tggaaaagga gttcatcttt attatgttgg
1261 aggggaggtg tatgccgaat gccttagtga cagtagcatc tttgtgcaaa gtcggaactg
1321 caactaccat catggatttc atcctactac tgtttgcaag atccctagtg ggtgtagtct
1381 gaaaattttt aacaaccaag aatttgctca gttattggca cagtctgtga accatggatt
1441 tgagacagtc tatgagctta caaaaatgtg tactatacgt atgagctttg tgaagggctg
1501 gggagcagaa taccaccgcc aggatgttac tagcaccccc tgctggattg agatacatct
1561 gcacggcccc ctccagtggc tggataaagt tcttactcaa atgggttcac ctcataatcc
1621 tatttcatct gtatcttaaa tggccccagg catctgcctc tggaaaacta ttgagccttg
1681 catgtacttg aaggatggat gagtcagaca cgattgagaa ctgacaaagg agccttgata
1741 atacttgacc tctgtgacca actgttggat tcagaaattt aaacaaaaaa aaa
//