LOCUS HSU59423 1990 bp mRNA linear HUM 30-AUG-1996
DEFINITION Human Smad1 mRNA, complete cds.
ACCESSION U59423
VERSION U59423.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1990)
AUTHORS Lennon,G.G., Auffray,C., Polymeropoulos,M. and Soares,M.B.
TITLE The I.M.A.G.E. consortium: an integrated molecular analysis of
genomes and their expression
JOURNAL Genomics (1996) In press
REFERENCE 2 (bases 1 to 1990)
AUTHORS Liu,F., Hata,A., Baker,J.C., Doody,J., Carcamo,J., Harland,R.M. and
Massague,J.
TITLE A human Mad protein acting as a BMP-regulated transcriptional
activator
JOURNAL Nature 381 (6583), 620-623 (1996)
PUBMED 8637600
REFERENCE 3 (bases 1 to 1990)
AUTHORS Liu,F.
TITLE Direct Submission
JOURNAL Submitted (28-MAY-1996) Cell Biology and Genetics Program, Memorial
Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY
10021, USA
FEATURES Location/Qualifiers
source 1..1990
/db_xref="H-InvDB:HIT000220586"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 433..1830
/note="Sma and Mad homolog"
/codon_start=1
/product="Smad1"
/protein_id="AAB06852.1"
/translation="MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKK
KGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHE
LKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG
QNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQM
PADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVY
YELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGV
HLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLL
AQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKV
LTQMGSPHNPISSVS"
BASE COUNT 526 a 517 c 478 g 469 t
ORIGIN
1 gaattccggg ggtattggca gctgaggagt ggaggctggg cagctccgac tccctgacgc
61 cagcgcgacc agatcaatcc aggctccagg agaaagcagg cgggcgggcg gagaaaggag
121 aggccgagcg gctcaacccg ggccgaggct cggggagcgg agagtggcgc accgcccggc
181 cgtccggacc cgggccgcga gaccccgctc gcccggccac tcgtgctccc gcacggacgg
241 gcgcgccgcc aacccggtgc tgactgggtt acttttttaa acactaggaa tggtaatttc
301 tactcttctg gacttcaaac taagaagtta aagagacttc tctgtaaata aacaaatctc
361 ttctgctgtc cttttgcatt tggagacagc tttatttcac catatccaag gagtataact
421 agtgctgtca ttatgaatgt gacaagttta ttttccttta caagtccagc tgtgaagaga
481 cttcttgggt ggaaacaggg cgatgaagaa gaaaaatggg cagagaaagc tgttgatgct
541 ttggtgaaaa aactgaagaa aaagaaaggt gccatggagg aactggaaaa ggccttgagc
601 tgcccagggc aaccgagtaa ctgtgtcacc attccccgct ctctggatgg caggctgcaa
661 gtctcccacc ggaagggact gcctcatgtc atttactgcc gtgtgtggcg ctggcccgat
721 cttcagagcc accatgaact aaaaccactg gaatgctgtg agtttccttt tggttccaag
781 cagaaggagg tctgcatcaa tccctaccac tataagagag tagaaagccc tgtacttcct
841 cctgtgctgg ttccaagaca cagcgaatat aatcctcagc acagcctctt agctcagttc
901 cgtaacttag gacaaaatga gcctcacatg ccactcaacg ccacttttcc agattctttc
961 cagcaaccca acagccaccc gtttcctcac tctcccaata gcagttaccc aaactctcct
1021 gggagcagca gcagcaccta ccctcactct cccaccagct cagacccagg aagccctttc
1081 cagatgccag ctgatacgcc cccacctgct tacctgcctc ctgaagaccc catgacccag
1141 gatggctctc agccgatgga cacaaacatg atggcgcctc ccctgccctc agaaatcaac
1201 agaggagatg ttcaggcggt tgcttatgag gaaccaaaac actggtgctc tattgtctac
1261 tatgagctca acaatcgtgt gggtgaagcg ttccatgcct cctccacaag tgtgttggtg
1321 gatggtttca ctgatccttc caacaataag aaccgtttct gccttgggct gctctccaat
1381 gttaaccgga attccactat tgaaaacacc aggcggcata ttggaaaagg agttcatctt
1441 tattatgttg gaggggaggt gtatgccgaa tgccttagtg acagtagcat ctttgtgcaa
1501 agtcggaact gcaactacca tcatggattt catcctacta ctgtttgcaa gatccctagt
1561 gggtgtagtc tgaaaatttt taacaaccaa gaatttgctc agttattggc acagtctgtg
1621 aaccatggat ttgagacagt ctatgagctt acaaaaatgt gtactatacg tatgagcttt
1681 gtgaagggct ggggagcaga ataccaccgc caggatgtta ctagcacccc ctgctggatt
1741 gagatacatc tgcacggccc cctccagtgg ctggataaag ttcttactca aatgggttca
1801 cctcataatc ctatttcatc tgtatcttaa atggccccag catctgcctc tggaaaacta
1861 ttgagccttg catgtacttg aaggatggat gagtcagaca cgattgagaa ctgacaaagg
1921 agccttgata atacttgacc tctgtgacca actgttggat tcagaaattt aaacaaaaaa
1981 aaaaaaaaaa
//