LOCUS HSU59288 3485 bp mRNA linear HUM 09-NOV-2001
DEFINITION Human H-cadherin mRNA, complete cds.
ACCESSION U59288
VERSION U59288.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3485)
AUTHORS Lee,S.W.
TITLE H-cadherin, a novel cadherin with growth inhibitory functions and
diminished expression in human breast cancer
JOURNAL Nat. Med. 2 (7), 776-782 (1996)
PUBMED 8673923
REFERENCE 2 (bases 1 to 3485)
AUTHORS Lee,S.W.
TITLE Direct Submission
JOURNAL Submitted (24-MAY-1996) Medicine, Beth Israel/Harvard Institutes of
Medicine, 77 Ave. Louis Pasteur, Boston, MA 02215, USA
FEATURES Location/Qualifiers
source 1..3485
/db_xref="H-InvDB:HIT000220576"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16q24"
/cell_type="mammary epithelial cells"
CDS 217..2358
/note="cell-cell adhesion; cadherin family"
/codon_start=1
/product="H-cadherin"
/protein_id="AAB18911.1"
/translation="MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEF
IEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPH
AEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVG
KVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETT
DVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPA
TDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQ
DMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPT
TGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPL
VPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQ
HQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPAT
GTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHK
QAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSC
RNSKVDCNAAGALRFSLPSVLLLSLFSLACL"
BASE COUNT 976 a 874 c 797 g 838 t
ORIGIN
1 tgatccagag gcctgagctg cagagggcac aagagagaaa agatgtctta gaaagagctt
61 tgagaacatg ccttggctgc tggcagggac cttggatggg gtagtctaca cccggaagtg
121 cctgcctgcc atcctctagt ggctgccttg caaaatatgc tcagtgcagc cgcgtgcatg
181 aatgaaaacg ccgccgggcg cttctagtcg gacaaaatgc agccgagaac tccgctcgtt
241 ctgtgcgttc tcctgtccca ggtgctgctg ctaacatctg cagaagattt ggactgcact
301 cctggatttc agcagaaagt gttccatatc aatcagccag ctgaattcat tgaggaccag
361 tcaattctaa acttgacctt cagtgactgt aagggaaacg acaagctacg ctatgaggtc
421 tcgagcccat acttcaaggt gaacagcgat ggcggcttag ttgctctgag aaacataact
481 gcagtgggca aaactctgtt cgtccatgca cggacccccc atgcggaaga tatggcagaa
541 ctcgtgattg tcggggggaa agacatccag ggctccttgc aggatatatt taaatttgca
601 agaacttctc ctgtcccaag acaaaagagg tccattgtgg tatctcccat tttaattcca
661 gagaatcaga gacagccttt cccaagagat gttggcaagg tagtcgatag tgacaggcca
721 gaaaggtcca agttccggct cactggaaag ggagtggatc aagagcctaa aggaattttc
781 agaatcaatg agaacacagg gagcgtctcc gtgacacgga ccttggacag agaagtaatc
841 gctgtttatc aactatttgt ggagaccact gatgtcaatg gcaaaactct cgaggggccg
901 gtgcctctgg aagtcattgt gattgatcag aatgacaacc gaccgatctt tcgggaaggc
961 ccctacatcg gccacgtcat ggaagggtca cccacaggca ccacagtgat gcggatgaca
1021 gcctttgatg cagatgaccc agccaccgat aatgccctcc tgcggtataa tatccgtcaa
1081 cagacgcctg acaagccatc tcccaacatg ttctacatcg atcctgagaa aggagacatt
1141 gtcactgttg tgtcacctgc gctgctggac cgagagactc tggaaaatcc caagtatgaa
1201 ctgatcatcg aggctcaaga tatggctgga ctggatgttg gattaacagg cacggccaca
1261 gccacgatca tgatcgatga caaaaatgat cactcaccaa aattcaccaa gaaagagttt
1321 caagccacag tcgaggaagg agctgtggga gttattgtca atttgacagt tgaagataag
1381 gatgacccca ccacaggtgc atggagggct gcctacacca tcatcaacgg aaaccccggg
1441 cagagctttg aaatccacac caaccctcaa accaacgaag ggatgctttc tgttgtcaaa
1501 ccattggact atgaaatttc tgccttccac accctgctga tcaaagtgga aaatgaagac
1561 ccactcgtac ccgacgtctc ctacggcccc agctccacag ccaccgtcca catcactgtc
1621 ctggatgtca acgagggccc agtcttctac ccagacccca tgatggtgac caggcaggag
1681 gacctctctg tgggcagcgt gctgctgaca gtgaatgcca cggaccccga ctccctgcag
1741 catcaaacca tcaggtattc tgtttacaag gacccagcag gttggctgaa tattaacccc
1801 atcaatggga ctgttgacac cacagctgtg ctggaccgtg agtccccatt tgtcgacaac
1861 agcgtgtaca ctgctctctt cctggcaatt gacagtggca accctcccgc tacgggcact
1921 gggactttgc tgataaccct ggaggacgtg aatgacaatg ccccgttcat ttaccccaca
1981 gtagctgaag tctgtgatga tgccaaaaac ctcagtgtag tcattttggg agcatcagat
2041 aaggatcttc acccgaatac agatcctttc aaatttgaaa tccacaaaca agctgttcct
2101 gataaagtct ggaagatctc caagatcaac aatacacacg ccctggtaag ccttcttcaa
2161 aatctgaaca aagcaaacta caacctgccc atcatggtga cagattcagg gaaaccaccc
2221 atgacgaata tcacagatct cagggtacaa gtgtgctcct gcaggaattc caaagtggac
2281 tgcaacgcgg cgggggccct gcgcttcagc ctgccctcag tcctgctcct cagcctcttc
2341 agcttagctt gtctgtgaga actcctgacg tctgaagctt gactcccaag tttccatagc
2401 aacaggaaaa aaaaaaaatc tatccaaatc tgaagattgc ggtttacagc tatcgaactt
2461 cacaactagg cctcaattgt tccggttttt tattttcttt acaatttcac ttagtctgta
2521 cttcatcatt ttgacagcat cttcctccct cctttaatta atggaatctt ctgaattttc
2581 cctgaatgtt taaagatcat gacatatgac ttgatcttct gggagcagga acaatgacta
2641 ctttttctgg tgtgttaaca tgtcgctagc cagtgctcca ggcacccagc tttgtctgtg
2701 ggttagtatt ggtgtatgta tgagtatctg tatgtatata tacacggtat ttatagagag
2761 agactatctg gagaagcctc gttttgatgc cattcttcct tgcaaggtta agcaaggtgg
2821 gtggaaacta agacacctga accctccagc ctcccgcatc aaggtcagca tgaggacaga
2881 ccacagagct gtcacttttg ctccgaagct acttctccac tgtcccgttc agtctgaatg
2941 tgccacaacc agccaggcag gtccacagag agggagagca gagaaagaag tcctttctct
3001 ttattgagtt cgaggactac aaccaattta cactgccatc tgatgccgtg atcctgagcc
3061 aaggaggtga ggagcagagc aggcaatttc accaccaaat gccaagaaaa gggctgacat
3121 tttctttcat gggcaccaac ctgcatttgt atgtgtcccg aatccacagt cgtactgatt
3181 ctaatgggga cacagatcat ggtagagaat ctctccctcc tcagtaaatg tacaactgca
3241 cctgttatca tggaggtcat acatggatac aaagaggtgt acaggtacca tcttgtatac
3301 acatatatac ccacatgtac agacatacat ttatgcacat tcacgctgtt tgtttcatat
3361 atacaggcat aaaatagagt aaatacaggt agttttaaaa gtaccctttt gtgtgaattg
3421 actaccgttg tttgcaaacc cgaaaataaa agacgttcat tatgtatgaa aaaaaaaaaa
3481 aaaaa
//