LOCUS HSU58852 3840 bp mRNA linear HUM 20-JUN-1996
DEFINITION Human NPAT mRNA, complete cds.
ACCESSION U58852
VERSION U58852.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3840)
AUTHORS Chen,X., Yang,L., Udar,N., Liang,T., Xu,S., Uhrhammer,N., Bay,J.O.,
Wang,Z., Dandakar,U., Chiplunkar,S., Klisak,I., Telatar,M.,
Yang,H., Concannon,P. and Gatti,R.A.
TITLE A novel gene immediately adjacent and in opposite transcriptional
orientation to the ATM gene at 11q23.1
JOURNAL Mamm. Genome (1996) In press
REFERENCE 2 (bases 1 to 3840)
AUTHORS Chen,X., Yang,L., Udar,N., Liang,T., Xu,S., Uhrhammer,S., Bay,J.O.,
Wang,Z., Dandakar,U., Chiplunkar,S., Klisak,I., Telatar,M.,
Yang,H., Concannon,P. and Gatti,R.A.
TITLE Direct Submission
JOURNAL Submitted (20-MAY-1996) X. Chen, Pediatrics, Cedars-Sinai Medical
Center, 8723 Alden Drive, Los Angeles, CA CA90048, USA
FEATURES Location/Qualifiers
source 1..3840
/db_xref="H-InvDB:HIT000220557"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11q22.3-23.1"
/clone_lib="Stratagene cDNA library (Catalog#936206) in
the lambda ZAP II vector"
gene 1..3840
/gene="NPAT"
CDS 1..3528
/gene="NPAT"
/note="predicted amino acids have three regions which
share similarity to annotated domains of transcriptional
factor oct-1, nucleolus-cytoplasm shuttle phosphoprotein
and protein kinases"
/codon_start=1
/protein_id="AAB02735.1"
/translation="MLLPSDVARLVLGYLQQENLIYTCQTFILESSDLKEYAEHCTDE
GFIPACLLSLFGKNLTTILNEYVAMKTKETSNNVPAIMSSLWKKLDHTLSQIRSMQSS
PRFAGSQRARTRTGIAEIKRQRKLASQTAPASAELLTLPYLSGQFTTPPSTGTQVTRP
SGQISDPSRSYFVVVNHSQSQDTVTTGEALNVIPGAQEKKAHASLMSPGRRKSESQRK
STTLSGPHSTIRNFQDPNAFAVEKQMVIENAREKILSNKSLQEKLAENINKFLTSDNN
IAQVPKQTDNNPTEPETSIDEFLGLPSEIHMSEEAIQDILEQTESDPAFQALFDLFDY
GKTKNNKNISQSISSQPMESNPSIVLADETNLAVKGSFETEESDGQSGQPAFCTSYQN
DDPLNALKNSNNHDVLRQEDQENFSQISTSIQKKAFKTAVPTEQKCDIDITFESVPNL
NDFNQRGNSNAECNPHCAELYTNQMSTETEMAIGIEKNSLSSNVPSESQLQPDQPDIP
ITSFVSLGCEANNENLILSGKSSQLLSQDTSLTGKPSKKSQFCENSNDTVKLKINFHG
SKSSDSSEVHKSKIEINVLEPVMSQLSNCQDNSCLQSEILPVSVESSHLNVSGQVEIH
LGDSLSSTKQPSNDSASVELNHTENEAQASKSENSQEPSSSVKEENTIFLSLGGNANC
EKVALTPPEGTPVENSHSLPPESVCSSVGDSHPESQNTDDKPSSNNSAEIDASNIVSL
KVIISDDPFVSSDTELTSAVSSINGENLPTIILSSPTKSPTKNAELVKCLSSEETVGA
VVYAEVGDSASMEQSLLTFKSEDSAVNNTQNEDGIAFSANVTPCVSKDGGYIQLMPAT
STAFGNSNNILIATCVTDPTALGTSVSQSNVVVLPGNSAPMTAQPLPPQLQTPPRSNS
VFAVNQAVSPNFSQGSAIIIASPVQPVLQGMVGMIPVSVVGQNGNNFSTPPRQVLHMP
LTAPVCNRSIPQFPVPPKSQKAQGLRNKPCIGKQVNNLVDSSGHSVGCHAQKTEVSDK
SIATDLGKKSEETTVPFPEESIVPAAKPCHRRVLCFDSTTAPVANTQGPNHKMVSQNK
ERNAVSFPNLDSPNVSSTLKPPSNNAIKREKEKPPLPKILSKSESAISRHTTIRETQS
EKKVSPTEIVLESFHKATANKENGDILSS"
misc_feature 169..1566
/gene="NPAT"
/note="encodes region similar to annotated domains of
transcriptional factor oct-1"
misc_feature 1825..2541
/gene="NPAT"
/note="encodes region similar to annotated domains of
nucleolus-cytoplasm shuttle phosphoprotein"
misc_feature 3013..3525
/gene="NPAT"
/note="encodes region similar to annotated domains of
protein kinases, including members of the PI-3 kinase
family"
BASE COUNT 1245 a 806 c 691 g 1098 t
ORIGIN
1 atgttgttac cctcggacgt agcccggctt gtattgggtt acttacagca agaaaacctc
61 atttatacct gccagacttt tattttggaa agttcagatt taaaagaata tgcagaacat
121 tgtacagatg aagggtttat tccagcctgc ttactgtcct tatttggaaa aaacttgaca
181 acaattttaa atgagtatgt agctatgaaa acaaaagaaa catcaaataa tgtcccagca
241 ataatgtcat ctctatggaa gaaattggac catacacttt ctcagatcag gagcatgcaa
301 agttccccaa ggtttgctgg cagtcagaga gcccgaacga gaactggaat tgcagaaatc
361 aaacggcaga gaaagcttgc atctcaaaca gctccagcca gtgcagagtt gctcacttta
421 ccttaccttt caggacagtt taccactcct ccttccacag gtacacaggt tactcgacca
481 agtggccaaa tttcagatcc atcgaggtca tattttgtag tggtcaacca ctcacagtca
541 caagatactg taaccactgg agaagcttta aatgtcattc ctggtgctca ggaaaagaaa
601 gcacatgcca gtttaatgtc tcccggtaga cgcaaaagtg aatctcagag aaaaagtacc
661 actttgtctg gccctcattc aacaatacgg aatttccaag atccaaacgc ttttgcagta
721 gaaaaacaaa tggttattga aaatgcacgg gaaaaaatac taagcaacaa atctcttcaa
781 gaaaagctag cagaaaacat aaataaattt ttaactagtg ataacaatat tgcccaagta
841 cctaagcaaa cagataacaa ccctacggag ccagagactt caattgatga attcctagga
901 cttccgagtg aaattcacat gtctgaagaa gctatacagg acatattgga acagacagaa
961 tcagacccag catttcaggc actctttgat ctctttgact atggcaaaac aaagaataat
1021 aaaaatatat cacaaagtat ttccagtcaa cctatggaat ccaatcccag tatagtctta
1081 gcagatgaaa ctaatctagc agttaaaggt tcttttgaaa cagaagaatc tgatggtcag
1141 tctggtcagc ccgctttttg tacatcctat cagaatgatg acccattaaa tgctttgaag
1201 aatagcaaca accatgatgt gcttagacaa gaagaccagg aaaatttttc ccaaataagt
1261 accagcatac agaaaaaggc ctttaaaaca gctgtaccca ctgaacagaa gtgtgacatt
1321 gacattacct ttgagtccgt gcctaatttg aatgacttta accaaagagg gaattctaat
1381 gctgaatgta atccacattg tgctgaatta tacaccaatc agatgtccac tgaaactgaa
1441 atggctatag ggattgaaaa gaactctttg tcttcaaatg taccgagtga atctcagtta
1501 cagcctgatc agcctgatat accaataact tcatttgttt cacttggttg tgaagctaac
1561 aatgaaaact taattctctc tgggaagagt tctcaacttt tatcccaaga tacttcatta
1621 actggaaagc catctaaaaa aagtcaattt tgtgaaaatt ctaatgatac agtaaaactt
1681 aaaattaatt ttcatggttc caagtcatca gattctagtg aagttcacaa gagtaaaata
1741 gaaattaatg tgttagaacc agttatgtca cagctatcaa attgccaaga taattcttgt
1801 cttcaaagtg aaatactacc tgtgtctgtt gaaagttcac atttaaatgt atctggacaa
1861 gtagaaattc atcttggaga ttcgctgtct tctactaaac aaccatctaa tgattcagca
1921 tctgttgagt taaatcatac agaaaatgaa gctcaggcat ccaagtctga gaattcacag
1981 gagccttcat cttctgtaaa agaagagaat actatttttc tctctttagg tggaaatgct
2041 aactgtgaga aagttgcact gacgcctcca gaaggcactc ctgtagaaaa cagtcactct
2101 cttcctccag aatctgtgtg ttcttcagtg ggagattctc accctgagtc ccaaaatact
2161 gatgacaaac cttctagcaa caactcagca gagatagatg catcaaatat cgtctctctc
2221 aaagttatca ttagtgatga tccatttgtt tcctcagata ctgaacttac cagtgctgtt
2281 tctagtatta atggagaaaa cctgccaact ataatcttgt cttctcctac taaatcacct
2341 actaaaaatg cagaactagt taaatgccta tcttcagaag aaactgtagg tgctgttgta
2401 tatgccgaag taggggattc agcctcaatg gaacagagtc ttttaacatt caaatctgaa
2461 gactctgcag taaacaatac tcagaatgaa gatggcattg ctttttcagc taatgttaca
2521 ccatgtgttt ccaaggatgg aggatatata cagttgatgc cagccacaag cacagctttt
2581 ggcaattcaa ataacattct gatagctacc tgtgtgactg atccaacagc gttaggaaca
2641 tctgtaagtc agtctaatgt agtggtgttg cctggaaatt ctgcacctat gactgctcaa
2701 cctctaccac ctcagttaca gacaccacca aggtcaaaca gtgtatttgc tgtcaaccaa
2761 gctgtgtcac caaacttttc acaaggatct gccataataa ttgcctctcc agtccagcct
2821 gtactccaag gaatggtagg gatgatccca gtatctgtgg ttggacagaa tggaaataac
2881 ttttctactc ctcctcggca ggttcttcat atgcctttga cagcacctgt atgcaataga
2941 agtatccctc aattccccgt ccctccaaaa tctcagaagg ctcagggact aagaaacaag
3001 ccttgtatag gaaaacaagt aaataatttg gtggattcgt caggtcattc agttggatgt
3061 catgcacaaa aaactgaagt ttctgacaaa agtattgcca cagatcttgg gaaaaaatca
3121 gaagaaacca cagttccctt cccagaagag agtatagttc cagctgctaa accatgccac
3181 agacgtgtac tctgtttcga cagcactact gctcctgtgg caaatacgca ggggccaaac
3241 cataagatgg tgtcccaaaa caaagaaagg aatgcagtct cttttcctaa tcttgactca
3301 cccaatgtgt cctccacctt aaaaccccct tctaataatg ctatcaaaag agagaaagag
3361 aagcctcctc tgcctaagat tttatctaaa tcggaaagtg ccattagccg gcataccacc
3421 ataagagaaa ctcaatcaga aaagaaagtt tctccaacag aaattgtgct tgaatctttc
3481 cataaagcaa cagctaataa ggagaatggt gatatactat cttcttgatg tgcagtttta
3541 tttagttagc tagtattttg ttgaggactt ttgcatctat gctcatcagg gatagtggtc
3601 tgcagttttc tttttattat gtcctttcct ggttttgata ttagatcagg gaagatttcc
3661 tcaattgttt gttcaaataa gttttccaaa cttgtagcct tgtcttctcc ctcaggaatg
3721 ccaatcattc ttaggtttgg ccttttcaca taatctcata tttcttagag actttgtcca
3781 cttcttttga ttatttttct ttatctttgt ctaattggat aatttgaaag ccttgtcttg
//