LOCUS HSU58048 2474 bp mRNA linear HUM 24-OCT-1996
DEFINITION Human metallopeptidase PRSM1 mRNA, complete cds.
ACCESSION U58048
VERSION U58048.1
KEYWORDS zincin, metalloproteinase, gluzincin, procollagen type III
N-proteinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2474)
AUTHORS Scott,I.C., Halila,R., Jenkins,J.M., Mehan,S., Apostolou,S.,
Winqvist,R., Callen,D.F., Prockop,D.J., Peltonen,L. and Kadler,K.E.
TITLE Molecular cloning, expression and chromosomal localization of a
human gene encoding a 33 kDa putative metallopeptidase (PRSM1)
JOURNAL Gene 174 (1), 135-143 (1996)
PUBMED 8863740
REFERENCE 2 (bases 1 to 2474)
AUTHORS Scott,I.C., Halila,R., Jenkins,J.M., Mehan,S., Apostolou,S.,
Winqvist,R., Callen,D.F., Prockop,D.J., Peltonen,L. and Kadler,K.E.
TITLE Direct Submission
JOURNAL Submitted (13-MAY-1996) Karl E. Kadler, Wellcome Trust Centre for
Cell-Matrix Research, University of Manchester, School of
Biological Sciences, Oxford Road, Manchester, UK M13 9PT, England
FEATURES Location/Qualifiers
source 1..2474
/db_xref="H-InvDB:HIT000220518"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16q24.3"
/note="Identified by immune screening of a human placental
cDNA library."
CDS 41..997
/note="protease, metallo, 33 kDa, number 1;
immunolocalized to various human tissues and cell lines
including placenta, aorta, skin fibroblasts, fetal liver,
kidney and bone cells; Contains a HEXXH motif found in the
zincin superfamily of metallopeptidases. putative
metallopeptidase"
/codon_start=1
/product="PRSM1"
/protein_id="AAC50775.1"
/translation="MATAAGSRAPPLWRDRPPSSREEHPVRPEVGRRPRKSPPGAAWS
VRSPPGPDTARSWRPFSLSECCSCHCGHGRYPVPVEVHGEAAGEAGQEGGEGLQGGAG
QSEEGPSAEKCRVCPCVCRERHPQEERRCELASDGVPRRRSGLQGGHSCDYEGGDQEY
GPGDQSPGQGPEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGG
QPHHADRRGEWPGGAGPAQPAARGRLCRGRELCAQPGGPAVTEVGRLEELAVPRRCAP
PLPRDVLEGSCPLPTASCLCADPAGLRPAATLRLSPARPAWP"
BASE COUNT 433 a 760 c 763 g 518 t
ORIGIN
1 agcgactcac aaaaggtcct cggccacggc gtgcgtcacc atggcgaccg ccgccggcag
61 ccgcgccccg cccctctggc gggaccggcc accatcctct cgcgaggagc atcccgtgcg
121 accggaagtg gggcggcgac cccggaagtc cccgccgggt gcagcttggt cggttcgatc
181 gccgccggga cctgacaccg cccggagttg gcgtcccttc tccctctccg agtgctgctc
241 ctgtcattgt ggccatggac gataccctgt tccagttgaa gttcacggcg aagcagctgg
301 agaagctggc caagaaggcg gagaaggact ccaaggcgga gcaggccaaa gtgaagaagg
361 cccttctgca gaaaaatgta gagtgtgccc gtgtgtatgc cgagaacgcc atccgcaaga
421 agaacgaagg tgtgaactgg cttcggatgg cgtcccgcgt agacgcagtg gcctccaagg
481 tggacacagc tgtgactatg aagggggtga ccaagaatat ggcccaggtg accaaagccc
541 tggacaaggc cctgagcacc atggacctgc agaaggtctc ctcagtgatg gacaggttcg
601 agcagcaggt gcagaacctg gacgtccata catcggtgat ggaggactcc atgagctcgg
661 ccaccaccct gaccacgccg caggagcagg tggacagcct catcatgcag atcgccgagg
721 agaatggcct ggaggtgctg gaccagctca gccagctgcc cgagggcgcc tctgccgtgg
781 gcgagagctc tgtgcgcagc caggaggacc agctgtcacg gaggttggcc gccttgagga
841 actagccgtg ccccgccggt gtgcaccgcc tctgccccgt gatgtgctgg aaggctcctg
901 tcctctcccc accgcgtctt gcctttgtgc tgaccccgcg gggctgcggc cggcagccac
961 tctgcgtctc tcacctgcca ggcctgcgtg gccttagggt tgttcctgtt cttttaggtt
1021 gggcggtggg tctgtgtcct ggtgttgagt ttctgcaaat ttctgggggt gatttctgtg
1081 actctgggcc cacagcgggg aggccaagag gggccctgtg gactttcacc cagcactgtg
1141 ggggccttca gactctgggg cagcagacat gctgcttccc atcagccaga gggggtcagg
1201 gctgccctgt tgccaaacaa ctccctgagg cctctccgca ccacctcagc gggcaggagg
1261 tcccaccatg tggacagaca tagcccaagg aggcaccaca ggtctatgtg tgctggggga
1321 tgtcaggtgc cacccaacgc tgtcctggtg gtatttacaa tgacatcctc ctcctccatc
1381 actccagggg tggtgtctcg gccgccccta ccagctggct gagccccctg gcctcctgcg
1441 ctccctcact tccctcagtt cccaaagctg cccagtccat ggggacagaa ccgtcactca
1501 gatccacatt caagtgtgcc caccctgcag tcttcatcct cactcagctg ctgcctctgg
1561 aggtgccttt ggccacatgt gctgtgctgt ttgtctcctc gacagggagc ctgtccacca
1621 gcaggctgcg gtcccagcgg gtgcgtctgc agctcctccc cttgggcagg ctggttctcc
1681 cggaggacct ttccttgggg ccctgcttca tgacgatgct gcctgtgtca ccctctacca
1741 tctgtaaaca actgggtgcc ttccccgacc acaccccaat gccttcccag cttggaagcc
1801 aaggcagctg atgaagggag ctcaggagag ccgtcttcag ctgggctggg gttggggctg
1861 ctgtgaggaa aacctgccat tgtggccctg gagagtcacc agcagctctt gggaaggact
1921 tgctgggagg ctgagagagg ctttgggcac agcctgctgt cttttccatt tcctaaagtt
1981 tacttcattg tcttgaggct tccaggtttt gtttttgttt ttgccaaagt agaaaaggca
2041 ggtggtgggc ggctggcagg gagtgcgggt ccccgcccct cttcagtcct gccctcccct
2101 cctcagtcct gcccaccccg tgcagcccat gctgaggctg cagtggtgtc gtgggtgtta
2161 cgtgcaggaa cgtggagacc ctgacgtggg ctcactgcat ttggttttct tttcagaact
2221 tgggagcccc cagggagggg ctagtgttgg taggtcctag acgtggttcc ctccagcctc
2281 cccaaaatca accctggtgt tgagagaacg tccttctgtc catcgtgggt aacagccttg
2341 gggagggtgc agagctctgc agagccatgg gccaggtggg gctgcctcag tcctgtcccc
2401 ttgggcactg aggagagggg cccattcacc tttctcctag aatgctgttg taaataaaca
2461 aatggatccc tgga
//