LOCUS HSU57456 1695 bp mRNA linear HUM 30-JUL-1996
DEFINITION Human transforming growth factor-beta signaling protein-1 (bsp-1)
mRNA, complete cds.
ACCESSION U57456
VERSION U57456.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1695)
AUTHORS Lechleider,R.J., de Caestecker,M.P., Dehejia,A.,
Polymeropoulos,M.H. and Roberts,A.B.
TITLE Serine phosphorylation, chromosomal localization, and transforming
growth factor-beta signal transduction by human bsp-1
JOURNAL J. Biol. Chem. 271 (30), 17617-17620 (1996)
PUBMED 8663601
REFERENCE 2 (bases 1 to 1695)
AUTHORS Lechleider,R.J., de Caestecker, M.P., Dehejia,A.,
Polymeropoulos,M.H. and Roberts,A.B.
TITLE Direct Submission
JOURNAL Submitted (02-MAY-1996) R.J. Lechleider, Laboratory of
Chemoprevention, NCI, 41 Library Drive MSC 5055, Bethesda, MD
20892-5055, USA
FEATURES Location/Qualifiers
source 1..1695
/db_xref="H-InvDB:HIT000220489"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4q28"
/cell_line="MDA-MB-231 breast carcinoma cell line"
gene 1..1695
/gene="bsp-1"
CDS 153..1550
/gene="bsp-1"
/note="similar to Drosophila Mothers against
decapentaplegic protein, Swiss-Prot Accession Number
P42003"
/codon_start=1
/product="transforming growth factor-beta signaling
protein-1"
/protein_id="AAC50621.1"
/translation="MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKK
KGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHE
LKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG
QNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQM
PADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVY
YELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGV
HLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLL
AQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKV
LTQMGSPHNPISSVS"
BASE COUNT 458 a 425 c 370 g 442 t
ORIGIN
1 ttccatattt ttgtaatttc tactcttctg gacttcaaac taagaagtta aagagacttc
61 tctgtaaata aacaaatctc ttctgctgtc cttttgcatt tggagacagc tttatttcac
121 catatccaag gagtataact agtgctgtca ttatgaatgt gacaagttta ttttccttta
181 caagtccagc tgtgaagaga cttcttgggt ggaaacaggg cgatgaagaa gaaaaatggg
241 cagagaaagc tgttgatgct ttggtgaaaa aactgaagaa aaagaaaggt gccatggagg
301 aactggaaaa ggccttgagc tgcccagggc aaccgagtaa ctgtgtcacc attccccgct
361 ctctggatgg caggctgcaa gtctcccacc ggaagggact gcctcatgtc atttactgcc
421 gtgtgtggcg ctggcccgat cttcagagcc accatgaact aaaaccactg gaatgctgtg
481 agtttccttt tggttccaag cagaaggagg tctgcatcaa tccctaccac tataagagag
541 tagaaagccc tgtacttcct cctgtgctgg ttccaagaca cagcgaatat aatcctcagc
601 acagcctctt agctcagttc cgtaacttag gacaaaatga gcctcacatg ccactcaacg
661 ccacttttcc agattctttc cagcaaccca acagccaccc gtttcctcac tctcccaata
721 gcagttaccc aaactctcct gggagcagca gcagcaccta ccctcactct cccaccagct
781 cagacccagg aagccctttc cagatgccag ctgatacgcc cccacctgct tacctgcctc
841 ctgaagaccc catgacccag gatggctctc agccgatgga cacaaacatg atggcgcctc
901 ccctgccctc agaaatcaac agaggagatg ttcaggcggt tgcttatgag gaaccaaaac
961 actggtgctc tattgtctac tatgagctca acaatcgtgt gggtgaagcg ttccatgcct
1021 cctccacaag tgtgttggtg gatggtttca ctgatccttc caacaataag aaccgtttct
1081 gccttgggct gctctccaat gttaaccgga attccactat tgaaaacacc aggcggcata
1141 ttggaaaagg agttcatctt tattatgttg gaggggaggt gtatgccgaa tgccttagtg
1201 acagtagcat ctttgtgcaa agtcggaact gcaactacca tcatggattt catcctacta
1261 ctgtttgcaa gatccctagt gggtgtagtc tgaaaatttt taacaaccaa gaatttgctc
1321 agttattggc acagtctgtg aaccatggat ttgagacagt ctatgagctt acaaaaatgt
1381 gtactatacg tatgagcttt gtgaagggct ggggagcaga ataccaccgc caggatgtta
1441 ctagcacccc ctgctggatt gagatacatc tgcacggccc cctccagtgg ctggataaag
1501 ttcttactca aatgggttca cctcataatc ctatttcatc tgtatcttaa atggccccag
1561 gcatctgcct ctggaaaact attgagcctt gcatgtactt gaaggatgga tgagtcagac
1621 acgattgaga actgacaaag gagccttgat aatacttgac ctctgtgacc aactgttgga
1681 ttcagaaatt taaac
//