LOCUS MMU57324 1954 bp mRNA linear ROD 09-DEC-1996
DEFINITION Mus musculus PS-2 mRNA, complete cds.
ACCESSION U57324
VERSION U57324.1
KEYWORDS .
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 1954)
AUTHORS Vito,P., Lacana,E. and D'Adamio,L.
TITLE Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and
Alzheimer's disease gene ALG-3
JOURNAL Science 271 (5248), 521-525 (1996)
PUBMED 8560270
REFERENCE 2 (bases 1 to 1954)
AUTHORS Vito,P., Wolozin,B., Ganjei,J.K., Iwasaki,K., Lacana,E. and
D'Adamio,L.
TITLE Requirement of the familial Alzheimer's disease gene PS2 for
apoptosis. Opposing effect of ALG-3
JOURNAL J. Biol. Chem. 271 (49), 31025-31028 (1996)
PUBMED 8940094
REFERENCE 3 (bases 1 to 1954)
AUTHORS Vito,P., Lacana,E., Ganjei,K. and D'Adamio,L.
TITLE Direct Submission
JOURNAL Submitted (01-MAY-1996) Luciano D'Adamio, T-Cell Molecular Biology
Unit, LCMI/NIAID/NIH, Bld 4 Rm 431 9000 Rockville Pike, Bethesda,
MD 20892, USA
FEATURES Location/Qualifiers
source 1..1954
/organism="Mus musculus"
/mol_type="mRNA"
/db_xref="taxon:10090"
/chromosome="1"
gene 1..1954
/gene="PS-2"
CDS 42..1388
/gene="PS-2"
/note="formerly known as STM2; homolog of the Alzheimer's
disease gene"
/codon_start=1
/protein_id="AAC52937.1"
/translation="MLAFMASDSEEEVCDERTSLMSAESPTSRSCQEGRPGPEDGEST
AQWRTQESEEDCEEDPDRYACSGAPGRPSGLEEELTLKYGAKRVIMLFVPVTLCMIVV
VATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLY
KYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLAVWNFGAVGMVC
IHWKGPLALQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRM
LVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEP
SYPEAFEAPLPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACF
IAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI"
BASE COUNT 421 a 524 c 548 g 460 t
ORIGIN
1 ggcttctgga actccggttt tgagcagttg tttgacttac catgctcgca ttcatggcct
61 ctgacagcga ggaagaggtg tgtgatgagc ggacgtcctt gatgtcagcc gagagcccca
121 catctcgctc ctgccaggaa ggcaggccag gcccggagga tggagagagc actgcccagt
181 ggaggactca ggagagcgaa gaagactgtg aagaggaccc ggaccgctac gcatgcagtg
241 gggctcctgg gcgaccgtcg ggcctggagg aagagctgac cctcaagtat ggggcgaaac
301 gtgtgatcat gctattcgtg cctgtcacgc tgtgtatgat cgtggtggtg gccactatca
361 agtctgtgcg tttctacact gagaagaacg ggcagctcat ctacacgccc ttcacggagg
421 acacgccctc ggtgggccag cggctcctca actccgtgct taacaccctc atcatgatca
481 gcgtcatcgt agtcatgacc atcttcctcg tggtactcta caagtatcga tgctacaagt
541 tcatccatgg ctggctgatc atgtcctccc tgatgctcct cttcttgttc acctacatct
601 acctcgggga agtgctcaag acctacaatg tggccatgga ctatcccaca ctcttcctgg
661 ctgtctggaa cttcggggca gtgggcatgg tgtgcatcca ctggaagggg cctctagcgc
721 tgcagcaggc ttaccttatt gtgatcagcg cactcatggc cctggtgttc atcaagtacc
781 tgccggagtg gtctgcctgg gtcatcttgg gtgccatctc tgtgtacgat ctcgtggccg
841 tgctgtgccc caaagggcca ctgaggatgc tggtggaaac tgcccaggag agaaatgagc
901 ccatatttcc tgccctgata tactcatctg ccatggtgtg gacggtgggc atggcaaagc
961 tggacccctc ctctcaagga gcgctgcagc tcccctatga cccagagatg gaagaagact
1021 cctacgacag ttttggagaa ccctcatacc ctgaagcctt cgaagccccc ctgcctggct
1081 acccagggga ggagctggag gaggaggagg aaaggggcgt gaagctcggc ctgggagact
1141 tcatcttcta cagcgtcctg gtgggcaagg ctgcagccac tggcaacgga gactggaaca
1201 ctacgctggc ctgttttatc gccatcctca ttggcttgtg tctcaccctc ctgctgcttg
1261 ctgtgttcaa gaaggctctg cccgccctcc ccatctccat cacctttgga ctcatcttct
1321 acttctccac agacaacctg gtgcgccctt tcatggacac tctggcctcc caccagctct
1381 acatctgaca ggagccaggc gaggtccgag agctatgggg gcntcactgg atgcaggtgt
1441 atagttttac actctagtgc catatatttt ttaaagaaat tttctttcct tacaaaagaa
1501 gaagaaaaaa aaaaaaaaaa agaataaaaa cgtgtcgtgt ttacttcgtg atgaggaagc
1561 agaagccacc cttcggtgct acctgtcttg tcaccagact gcagcttgcc tgtcggagca
1621 tctgtggcgc cggtgggatg cttggatgct cagcaagcaa gcgtctcttc agggatgagg
1681 tcgtgtgtgg agcaggttgg ggaggatgca ggcccctgtc cacgtctgta agtctccagg
1741 gatgatcaga aggaacaggt gcattgtggg aaccaggagg cgccatcacc ctgaccagag
1801 gtggaaagcc cgtgtgcagt catgaatgtc cccagtgctg tgtttgtgat gtctgttact
1861 ttagaacctt agaagccaag tcctgttctt atttctgcag tgactgctgg gaagtggctt
1921 aataatgata ccaataaaca gatgctcctg ctgg
//