LOCUS HSU56637 2385 bp mRNA linear HUM 04-FEB-1998
DEFINITION Human capping protein alpha subunit isoform 1 mRNA, complete cds.
ACCESSION U56637
VERSION U56637.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2385)
AUTHORS Hart,M.C., Korshunova,Y.O. and Cooper,J.A.
TITLE Vertebrates have conserved capping protein alpha isoforms with
specific expression patterns
JOURNAL Cell Motil. Cytoskeleton 38 (2), 120-132 (1997)
PUBMED 9331217
REFERENCE 2 (bases 1 to 2385)
AUTHORS Hart,M.C., Korshunova,Y.O. and Cooper,J.A.
TITLE Direct Submission
JOURNAL Submitted (25-APR-1996) Marilyn C. Hart, Cell Biology & Physiology,
Washington University, Box 8228, 660 S. Euclid Ave., St. Louis, MO
63110, USA
FEATURES Location/Qualifiers
source 1..2385
/db_xref="H-InvDB:HIT000220459"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
source 1..33
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="testis"
/note="derived by RACE from RNA"
source 34..2385
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="G4021"
/tissue_type="heart"
/dev_stage="fetal"
/note="see also EST sequence, GenBank Accession Number
R58525"
source 812..2385
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="146582"
/tissue_type="placenta"
CDS 1..861
/function="binds barbed ends of actin filaments"
/codon_start=1
/product="capping protein alpha subunit isoform 1"
/protein_id="AAC00533.1"
/translation="MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDN
LLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLR
KEASDPQPEEADGGLKSWRESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIES
HQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTV
SNEAQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
YKIGKEMQNA"
regulatory 2268..2273
/regulatory_class="polyA_signal_sequence"
BASE COUNT 724 a 448 c 447 g 766 t
ORIGIN
1 atggccgact tcgatgatcg tgtgtcggat gaggagaagg tacgcatagc tgctaaattc
61 atcactcatg cacccccagg ggaatttaat gaagtattca atgacgttcg gctactactt
121 aataatgaca atctcctcag ggaaggggca gcacatgcat ttgcccagta taacatggat
181 cagttcacgc ctgtgaagat agaaggatat gaagatcagg tcttaattac agagcacggt
241 gacctgggta atagcagatt tttagatcca agaaacaaaa tttcctttaa atttgaccac
301 ttacggaaag aagcaagtga cccccagcca gaagaagcag atggaggtct gaagtcttgg
361 agagaatcct gtgacagtgc tttaagagcc tatgtgaaag accattattc caacggcttc
421 tgtactgttt atgctaaaac tatcgatggg caacagacta ttattgcatg tattgaaagc
481 caccagtttc agcctaaaaa cttctggaat ggtcgttgga gatcagagtg gaagttcacc
541 atcacaccac ctacagccca ggtggttggc gtgcttaaga ttcaggttca ctattatgaa
601 gatggcaatg ttcagttggt tagtcataaa gatgtacagg attcactaac tgtttcgaat
661 gaagcccaaa ctgccaagga gtttattaaa atcatagaga atgcagaaaa tgagtatcag
721 acagcaatta gtgaaaacta tcaaacaatg tcagatacca cattcaaggc cttgcgccgc
781 cagcttccag ttacccgcac caaaatcgac tggaacaaga tactcagcta caagattggc
841 aaagaaatgc agaatgctta aaggctgaat gtaggattct tcagtatgtg gaaagacaag
901 gattcaacgt gtggtcatat gataaataag tgatttataa acaagagtga tattttgcta
961 gggctttcaa agttaaccgg ttttctagcc tcatggaata ctgttgaacc tatagcgttg
1021 tcttgattct tttgtgttct ctgccttgta attttctgtt actgctatat ctacgtgtaa
1081 atcttttttt cttttttttt tttttttttt ttcttttttg gttaattctg ccacatttaa
1141 tgttggtgag agagtgatct atcctaatga catttactgt ttaaaaaagt ttcctagcca
1201 tgaagccctg ctactgattt agacaaggta ttatggtcat tactttgtac ccctatcctt
1261 ccaagcactt ctggtacttc agtcgttttt actgatccac caacacctaa agaggctatg
1321 ctacagtctc tagctaaatg gaagacacat tcatccttct ccctctgact gctttgatca
1381 tcatttattg catcgtcata tcatatttat cgcatctcat aactaacttt ctaaagtttg
1441 gattgggact tttcaggtcc tttttggagg gcaaaggaag ttccagcttc tctggggaac
1501 ttgtttttaa atccaaagac ttgaaccaca ttccctgcac atgaacatgt ttgcttttat
1561 cccttctctc attggctcct tcccatctta gtaccattgt agttatacat ctgcattttt
1621 tagaagcatt ttacccattt atttttttaa acattcaaga actgctgacg tactgtggat
1681 gtagagtata aaacttgaaa aatgcagatg ttgaaggaat aataggtatc ttgtgcttta
1741 atactttatg gcaggattgt actataagca aatgaattaa acagctatgt aaatcataaa
1801 gaaaaactaa aaatgaacca aagtgaaagg ataacttcca ggcagtatct ttctattgta
1861 acctgttatt taaggaaata ctagtgattt cttctaaata ggatgtaaac ttctttcaaa
1921 ttactcttcc tcagtctgcc tgccaagaac tcaagtgtaa ctgtgataaa ataacctttc
1981 ccaggtatat tcggcaggta tgtgtgtaat ctcagaatac acaggtgaca tagatatgat
2041 atgacaactg gtaatggtgg attcatttac attgtttaca cttctatgac caggccttaa
2101 gggaaggtca gttttttaaa aaaccaagta gtgtcttcct acctatctcc agatacatgt
2161 caaaaagaaa aggtgtttgt gctccgtttt gtttctgctc agtaatatag tcaagcaagt
2221 ttgttccagg tgacccattg agctgtgtat gcatttttgt ttatttcaat aaaatatatt
2281 tgtattattt gtccttcata ctatccatcc ataccacact atcttctgta tcaggtagtc
2341 taatagaaat atacctgttt tgttctaaaa aaaaaaaaaa aaaaa
//