LOCUS HSU56417 2242 bp mRNA linear HUM 04-JUN-1997
DEFINITION Human lysophosphatidic acid acyltransferase-alpha mRNA, complete
cds.
ACCESSION U56417
VERSION U56417.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2242)
AUTHORS West,J., Tompkins,C.K., Balantac,N., Nudelman,E., Meengs,B.,
White,T., Bursten,S., Coleman,J., Kumar,A., Singer,J.W. and
Leung,D.W.
TITLE Cloning and expression of two human lysophosphatidic acid
acyltransferase cDNAs that enhance cytokine-induced signaling
responses in cells
JOURNAL DNA Cell Biol. 16 (6), 691-701 (1997)
PUBMED 9212163
REFERENCE 2 (bases 1 to 2242)
AUTHORS Leung,D.W., Tompkin,C. and West,J.
TITLE Direct Submission
JOURNAL Submitted (24-APR-1996) David W. Leung, Molecular Biology, Cell
Therapeutics, Inc., 201 Elliott Ave. W., Suite 400, Seattle, WA
98119, USA
FEATURES Location/Qualifiers
source 1..2242
/db_xref="H-InvDB:HIT000220450_05"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 319..1170
/function="converts lysophosphatidic acid to phosphatidic
acid in the presence of acyl-CoA"
/note="LPAAT-a; 1-acyl-sn-glycerol-3-phosphate
acyltransferase; similar to sequence within class III MHC
locus on chromosome 6 deposited in GenBank Accession
Number U89336"
/codon_start=1
/product="lysophosphatidic acid acyltransferase-alpha"
/protein_id="AAB58775.1"
/translation="MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGW
ILFLAVLAIPVCAVRGRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVS
NHQSSLDLLGMMEVLPGRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMS
EVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYC
KKERRFTSGQCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYL
KKPGGGG"
BASE COUNT 428 a 726 c 582 g 506 t
ORIGIN
1 ggaagtcagc aggcgttggg gaggggtggc gggggaatag cggcggcagc agccccagcc
61 ctcagagaga cagcagaaag ggagggaggg agggtgctgg ggggacagcc ccccaccatt
121 cctaccgcta tgggcccaac ctcccactcc cacctcccct ccatcggccg gggctaggac
181 acccccaaat cccgtcgccc ccttggcacc gacaccccga cagagacaga gacacagcca
241 tccgccacca ccgctgccgc agcctggctg gggagggggc cagcccccca ggccccctac
301 ccctctgagg tggccagaat ggatttgtgg ccaggggcat ggatgctgct gctgctgctc
361 ttcctgctgc tgctcttcct gctgcccacc ctgtggttct gcagccccag tgccaagtac
421 ttcttcaaga tggccttcta caatggctgg atcctcttcc tggctgtgct cgccatccct
481 gtgtgtgccg tgcgaggacg caacgtcgag aacatgaaga tcttgcgtct aatgctgctc
541 cacatcaaat acctgtacgg gatccgagtg gaggtgcgag gggctcacca cttccctccc
601 tcgcagccct atgttgttgt ctccaaccac cagagctctc tcgatctgct tgggatgatg
661 gaggtactgc caggccgctg tgtgcccatt gccaagcgcg agctactgtg ggctggctct
721 gccgggctgg cctgctggct ggcaggagtc atcttcatcg accggaagcg cacgggggat
781 gccatcagtg tcatgtctga ggtcgcccag accctgctca cccaggacgt gagggtctgg
841 gtgtttcctg agggaacgag aaaccacaat ggctccatgc tgcccttcaa acgtggcgcc
901 ttccatcttg cagtgcaggc ccaggttccc attgtcccca tagtcatgtc ctcctaccaa
961 gacttctact gcaagaagga gcgtcgcttc acctcgggac aatgtcaggt gcgggtgctg
1021 cccccagtgc ccacggaagg gctgacacca gatgacgtcc cagctctggc tgacagagtc
1081 cggcactcca tgctcactgt tttccgggaa atctccactg atggccgggg tggtggtgac
1141 tatctgaaga agcctggggg cggtgggtga accctggctc tgagctctcc tcccatctgt
1201 ccccatcttc ctccccacac ctacccaccc agtgggccct gaagcagggc caaaccctct
1261 tccttgtctc ccctctcccc acttattctc ctctttggaa tcttcaactt ctgaagtgaa
1321 tgtggataca gcgccactcc tgccccctct tggccccatc catggactct tgcctcggtg
1381 cagtttccac tcttgacccc cacctcctac tgtcttgtct gtgggacagt tgcctccccc
1441 tcatctccag tgactcagcc tacacaaggg aggggaacat tccatcccca gtggagtctc
1501 ttcctatgtg gtcttctcta cccctctacc cccacattgg ccagtggact catccattct
1561 ttggaacaaa tcccccccca ctccaaagtc catggattca atggactcat ccatttgtga
1621 ggaggacttc tcgccctctg gctggaagct gatacctgaa gcactcccag gctcatcctg
1681 ggagctttcc tcagcacctt caccttccct cccagtgtag cctcctgtca gtgggggctg
1741 gacccttcta attcagaggt ctcatgcctg cccttgccca gatgcccagg gtcgtgcact
1801 ctctgggata ccagttcagt ctccacattt ctggttttct gtccccatag tacagttctt
1861 cagtggacat gaccccaccc agccccctgc agccctgctg accatctcac cagacacaag
1921 gggaagaagc agacatcagg tgctgcactc acttctgccc cctggggagt tggggaaagg
1981 aacgaaccct ggctggaggg gataggaggg cttttaattt atttcttttt ctgttgaggc
2041 ttccccctct ctgagccagt tttcatttct tcctggtggc attagccact ccctgcctct
2101 cactccagac ctgttcccac aactggggag gtaggctggg agcaaaagga gagggtggga
2161 cccagttttg cgtggttggt ttttattaat tatctggata acagcaaaaa aactgaaaat
2221 aaagagagag agaaaaaaaa aa
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