LOCUS HSU56390 1481 bp mRNA linear HUM 16-AUG-1996
DEFINITION Human cysteine protease ICE-LAP6 mRNA, complete cds.
ACCESSION U56390
VERSION U56390.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1481)
AUTHORS Duan,H., Orth,K., Chinnaiyan,A.M., Poirier,G.G., Froelich,C.J.,
He,W.W. and Dixit,V.M.
TITLE ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated
by the cytotoxic T cell protease granzyme B
JOURNAL J. Biol. Chem. 271 (28), 16720-16724 (1996)
PUBMED 8663294
REFERENCE 2 (bases 1 to 1481)
AUTHORS Duan,H., Orth,K., Chinnaiyan,A.M., Poirier,G.G., Froelich,C.J.,
He,W.W. and Dixit,V.M.
TITLE Direct Submission
JOURNAL Submitted (23-APR-1996) H. Duan, Pathology, University of Michigan,
1301 Catherine St., Ann Arbor, MI 48109, USA
FEATURES Location/Qualifiers
source 1..1481
/db_xref="H-InvDB:HIT000220448"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 4..1254
/note="cysteine protease"
/codon_start=1
/product="ICE-LAP6"
/protein_id="AAC50640.1"
/translation="MDEADRRLLRRCRLRLVEELQVDQLWDVLLSRELFRPHMIEDIQ
RAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAGKLSKPT
LENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPC
GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLE
LARQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLG
GKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISS
LPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVS
VKGIYKQMPGCFNFLRKKLFFKTS"
BASE COUNT 308 a 407 c 431 g 335 t
ORIGIN
1 gccatggacg aagcggatcg gcggctcctg cggcggtgcc ggctgcggct ggtggaagag
61 ctgcaggtgg accagctctg ggacgtcctg ctgagccgcg agctgttcag gccccatatg
121 atcgaggaca tccagcgggc aggctctgga tctcggcggg atcaggccag gcagctgatc
181 atagatctgg agactcgagg gagtcaggct cttcctttgt tcatctcctg cttagaggac
241 acaggccagg acatgctggc ttcgtttctg cgaactaaca ggcaagcagg aaagttgtcg
301 aagccaaccc tagaaaacct taccccagtg gtgctcagac cagagattcg caaaccagag
361 gttctcagac cggaaacacc cagaccagtg gacattggtt ctggaggatt cggtgatgtc
421 ggtgctcttg agagtttgag gggaaatgca gatttggctt acatcctgag catggagccc
481 tgtggccact gcctcattat caacaatgtg aacttctgcc gtgagtccgg gctccgcacc
541 cgcactggct ccaacatcga ctgtgagaag ttgcggcgtc gcttctcctc gctgcatttc
601 atggtggagg tgaagggcga cctgactgcc aagaaaatgg tgctggcttt gctggagctg
661 gcgcggcagg accacggtgc tctggactgc tgcgtggtgg tcattctctc tcacggctgt
721 caggccagcc acctgcagtt cccaggggct gtctacggca cagatggatg ccctgtgtcg
781 gtcgagaaga ttgtgaacat cttcaatggg accagctgcc ccagcctggg agggaagccc
841 aagctctttt tcatccaggc ctgtggtggg gagcagaaag accatgggtt tgaggtggcc
901 tccacttccc ctgaagacga gtcccctggc agtaaccccg agccagatgc caccccgttc
961 caggaaggtt tgaggacctt cgaccagctg gacgccatat ctagtttgcc cacacccagt
1021 gacatctttg tgtcctactc tactttccca ggttttgttt cctggaggga ccccaagagt
1081 ggctcctggt acgttgagac cctggacgac atctttgagc agtgggctca ctctgaagac
1141 ctgcagtccc tcctgcttag ggtcgctaat gctgtttcgg tgaaagggat ttataaacag
1201 atgcctggtt gctttaattt cctccggaaa aaacttttct ttaaaacatc ataaggccag
1261 ggcccctcac cctgccttat cttgcacccc caaagctttc ctgccccagg cctgaaagag
1321 gctgaggcct ggactttcct gcaactcaag gactttgcag ccggcacagg gtctgctctt
1381 tctctgccag tgacagacag gctcttagca gcttccagat tgacgacaag tgctgaacag
1441 tggaggaaga gggacagatg aatgccgtgg attgcacgtg g
//