LOCUS HSU54996 2883 bp mRNA linear HUM 04-DEC-1997
DEFINITION Human protein ZW10 homolog (HZW10) mRNA, complete cds.
ACCESSION U54996
VERSION U54996.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2883)
AUTHORS Starr,D.A., Williams,B.C., Li,Z., Etemad-Moghadam,B., Dawe,R.K. and
Goldberg,M.L.
TITLE Conservation of the centromere/kinetochore protein ZW10
JOURNAL J. Cell Biol. 138 (6), 1289-1301 (1997)
PUBMED 9298984
REFERENCE 2 (bases 1 to 2883)
AUTHORS Starr,D.A., Williams,B.C., Li,Z. and Goldberg,M.L.
TITLE Direct Submission
JOURNAL Submitted (13-APR-1996) D.A. Starr, Genetics and Development,
Cornell University, 427 Biotechnology Building, Ithaca, NY 14853,
USA
FEATURES Location/Qualifiers
source 1..2883
/db_xref="H-InvDB:HIT000220331"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
gene 1..2883
/gene="HZW10"
CDS 24..2363
/gene="HZW10"
/note="Centromere binding protein at prophase, metaphase,
and early anaphase. Also binds kinetochore microtubules at
metaphase; homolog of Drosophila melanogaster gene
l(1)zw10, protein ZW10, PIR Accession Number A43275"
/codon_start=1
/product="HZW10"
/protein_id="AAB88237.1"
/translation="MASFVTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISK
KYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERD
SVVLSLLKQLQEFSTAIEEYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILK
SLSMELTIQKQNILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEK
TPMPPISSVLLAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIR
FESIMTNLEYPSPSEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMI
WEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYA
RNINSHFANKKCQDVIVAARNLMTSEIHNTVKIIPDSKINVPELPTPDEDNKLEVQKV
SNTQYHEVMNLEPENTLDQHSFSLPTCRISESVKKLMELAYQTLLEATTSSDQCAVQL
FYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPI
LCDGTATFVDLVPGFRRLGTECFLAQMRAQKGELLERLSSARNFSNMDDEENYSAASK
AVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTAISEVIGKITALEDISTEDGDRL
YSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKWMPFKELMMMLQASLQEIGDR
WADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK"
BASE COUNT 886 a 578 c 639 g 780 t
ORIGIN
1 gcacgagggt tcccgtcttg gccatggcct cgttcgtgac agaagttttg gcacactccg
61 ggaggctgga aaaggaggat ctggggaccc ggatcagccg cctgacccgg cgggtggagg
121 agatcaaggg tgaggtgtgc aatatgatta gcaagaagta cagtgaattc ctgcctagca
181 tgcagagcgc gcagggcctg attacccagg tggataagct atctgaagac attgacctgc
241 tgaaatccag gatagagagt gaggtccgcc gggatcttca cgtatcaacc ggtgaattta
301 cagacttaaa gcagcagttg gaaagagact cagttgtcct aagtttgctt aaacagttgc
361 aggagttttc cactgctatt gaagaatata attgtgcatt aacagagaag aagtatgtca
421 ctggtgctca gcgtctggaa gaggcacaga aatgcttgaa gttattaaaa tccagaaaat
481 gctttgattt aaaaatattg aaatctctca gcatggagct cacaatacag aaacagaaca
541 tactttatca ccttggagaa gagtggcaga agctgattgt atggaagttc ccaccatcaa
601 aagataccag cagtttggaa tcttacctac aaactgaact tcatttatac actgaacaat
661 cgcacaaaga ggagaagacc cctatgccac ccatcagttc tgtcctcttg gcattttctg
721 ttcttggaga actacacagc aagcttaaat catttggtca gatgctgctg aagtatatcc
781 ttaggccgct ggcatcttgc ccatcccttc atgctgtgat agaaagccag cctaacatag
841 ttattattcg ttttgaatct ataatgacta acttggaata tccatcacca tctgaagttt
901 ttacaaagat cagactggta ctagaagtgc tccagaaaca gcttctagat ttgccacttg
961 acactgacct ggaaaatgaa aaaacatcta ctgtcccatt ggctgagatg cttggagaca
1021 tgatctggga ggacttgtct gagtgcctca tcaaaaactg tttggtttat tcgattccaa
1081 caaatagcag caaattacag caatatgaag agatcataca gtccactgaa gaatttgaaa
1141 atgccctaaa ggaaatgaga tttttaaaag gagatactac agatttgctg aaatacgctc
1201 gtaacatcaa ttctcatttt gcaaacaaaa agtgccagga tgtgattgtg gcagccagaa
1261 atctaatgac ctcagaaatt cataacactg tgaagattat tcctgattct aagataaatg
1321 tgccagagtt acccactcct gatgaggata acaaactgga agtacagaaa gtatccaata
1381 ctcagtacca cgaagtgatg aatttagagc ctgaaaatac attggaccaa cattcctttt
1441 ccttgcccac atgccgtatc agtgagtctg tgaagaaatt aatggaactc gcctatcaga
1501 ctttactaga ggcaacaacc agtagtgatc aatgtgctgt tcaacttttc tactcagtga
1561 ggaatatctt ccatttgttc catgatgttg taccaacata tcacaaggag aaccttcaaa
1621 aacttcccca gttggctgct attcatcaca acaactgtat gtacattgct caccacttgc
1681 tgaccctcgg gcatcagttc agattgcgtc ttgcccccat tctttgtgat ggcactgcta
1741 cttttgtgga tcttgtacct ggcttcagga gacttgggac agaatgcttt ttggcccaaa
1801 tgcgggcaca gaaaggtgaa cttctggaaa gattatcaag tgctaggaac ttttcaaata
1861 tggacgatga agagaattat tctgcagcaa gtaaagcagt ccggcaggta ctgcaccaac
1921 taaagagact tggaattgtg tggcaggatg tcctgccagt gaatatatat tgcaaggcta
1981 tggggacttt actcaataca gcaatttctg aggtcattgg caaaattact gccctagagg
2041 acatatctac tgaagatggt gataggttat attccttatg caaaacagtg atggatgaag
2101 gaccccaagt atttgcacct ttatctgaag aaagcaagaa caagaaatat caagaagagg
2161 ttccagtcta tgtgccaaaa tggatgccat tcaaggaatt gatgatgatg ctacaagcca
2221 gcttgcaaga aattggggat cggtgggcag atggaaaagg acccctggca gctgcgttct
2281 cttccagtga agtaaaagct ttaattcgtg ccttgtttca gaacacagaa agaagagcag
2341 ctgcccttgc taaaattaaa tagctccatc ttcttaagaa agctatgtct tgaatatgtg
2401 gattcttccc ttggcataat tactccctta aagacttctt tgaatcgccc attggttttg
2461 gtgaaccagt acatcttgga agtttgactt tacagaagaa cgtctacctc ctggcctgta
2521 cgaggctttg tttaagaact gtttattaag ataaattgtc aagtaaagca cctcaattca
2581 ttgactttct agccatcttc ctttgattag ctaacaaact gtcaggcagc attatttcat
2641 gctgcttcca gagcctctgg gagctatata cattgtaaat gcaggcccta gctttggaac
2701 gaggaattgg gagattccag gagtcagggt agagaatttc tgagcaaatc ggagatattt
2761 taggggtgtg gaggagggga agggaggaat gggccaccat atttggctta caggaattaa
2821 ggagacttcc tgtaatattt ctttccaata aatattgctt tttacaaaaa aaaaaaaaaa
2881 aaa
//