LOCUS HSU54617 1798 bp mRNA linear HUM 06-SEP-1996
DEFINITION Human pyruvate dehydrogenase kinase isoform 4 mRNA, complete cds.
ACCESSION U54617
VERSION U54617.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1798)
AUTHORS Rowles,J., Scherer,S.W., Xi,T., Majer,M., Nickle,D.C.,
Rommens,J.M., Popov,K.M., Harris,R.A., Riebow,N.L., Xia,J.,
Tsui,L., Bogardus,C. and Prochazka,M.
TITLE Cloning and characterization of PDK4 on 7q21.3 encoding a fourth
pyruvate dehydrogenase kinase isoenzyme in human
JOURNAL J. Biol. Chem. 271 (37), 22376-22382 (1996)
PUBMED 8798399
REFERENCE 2 (bases 1 to 1798)
AUTHORS Prochazka,M.
TITLE Direct Submission
JOURNAL Submitted (10-APR-1996) Michal Prochazka, CDNS/PECRB, NIDDK/NIH,
4212 N. 16th Street, Phoenix, AZ 85016, USA
FEATURES Location/Qualifiers
source 1..1798
/db_xref="H-InvDB:HIT000220320"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7q21.3"
/tissue_type="frontal cortex"
misc_feature 1..50
/note="determined by 5' RACE"
CDS 223..1458
/codon_start=1
/product="pyruvate dehydrogenase kinase isoform 4"
/protein_id="AAC50669.1"
/translation="MKAARFVLRSAGSLNGAGLVPREVEHFSRYSPSPLSMKQLLDFG
SENACERTSFAFLRQELPVRLANILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEF
HEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFLD
RFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQY
YLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPI
EVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGL
PISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPVFNKSAFKHYQMSSEA
DDWCIPSREPKNLAKEVAM"
BASE COUNT 500 a 440 c 393 g 465 t
ORIGIN
1 agacttgaac ttgaatctcg aaccactgca tctccgactc tgcccagact cttcactccg
61 cggcaccctc aaaccccagc ccaggccggg gcgcacaagc cagccagcgc acctgcagtc
121 ctcgcccgga cgcgccgcgc cccctcggaa ccaggctctg ctccgagcag ccttcgcccc
181 tcaagccagc cacagtcccc gccaggccgg gtgggcgtca agatgaaggc ggcccgcttc
241 gtgctgcgca gcgctggctc gctcaacggc gccggcctgg tgccccgaga ggtggagcat
301 ttctcgcgct acagcccgtc cccgctgtcc atgaagcagc tactggactt tggttcagaa
361 aatgcatgtg aaagaacttc ttttgcattt ttgcgacaag aattgcctgt gagactcgcc
421 aacattctga aggaaattga tatcctcccg acccaattag taaatacctc ttcagtgcaa
481 ttggttaaaa gctggtatat acagagcctg atggatttgg tggaattcca tgagaaaagc
541 ccagatgacc agaaagcatt atcagacttt gtagatacac tcatcaaagt tcgaaataga
601 caccataatg tagtccctac aatggcacaa ggaatcatag agtataaaga tgcctgtaca
661 gttgacccag tcaccaatca aaatcttcaa tatttcttgg atcgatttta catgaaccgt
721 atttctactc ggatgctgat gaaccagcac attcttatat ttagtgactc acagacagga
781 aacccaagcc acattggaag cattgatcct aactgtgatg tggtagcagt ggtccaagat
841 gcctttgagt gttcaaggat gctctgtgat cagtattatt tatcatctcc agaattaaag
901 cttacacaag tgaatggaaa atttccagac caaccaattc acatcgtgta tgttccttct
961 cacctccatc atatgctctt tgaactattt aagaatgcaa tgcgggcaac agttgaacac
1021 caggaaaatc agccttccct tacaccaata gaggttattg ttgtcttggg aaaagaagac
1081 cttaccatta agatttcaga cagaggaggt ggtgttcccc tgagaattat tgaccgcctc
1141 tttagttata catactccac tgcaccaacg cctgtgatgg ataattcccg gaatgctcct
1201 ttggctggtt ttggttacgg cttgccaatt tctcgtctgt atgcaaagta ctttcaagga
1261 gatctgaatc tctactcttt atcaggatat ggaacagatg ctatcatcta cttaaaggct
1321 ttgtcttctg agtctataga aaaacttcca gtttttaaca agtcagcctt caaacattat
1381 cagatgagct ctgaggctga tgactggtgt atcccaagca gggaaccaaa gaacctggca
1441 aaagaagtgg ccatgtgaag agggacactc aggacacttt acgggatcaa agtgggtcta
1501 caccagtgct gcttcctgaa tgtttgtgtg tgaacccttg tttcctccaa aacaaacgac
1561 agcaacgaaa actccttaat cagaacactg atccaatgag gaatggagct tgtttctgtg
1621 acccaggaga acttagtgca agactacagg agttaacaga tggccagctc cttatttttt
1681 aatgtagaat aactcctgag tttatatcaa atcctgaaga aataagcctc agttttccat
1741 ctgtttttga taagaataag aaagggagtg agtgtgaaga tggtggttag cagtttcg
//