LOCUS HSU53476 1469 bp mRNA linear HUM 19-MAY-1997
DEFINITION Human proto-oncogene Wnt7a mRNA, complete cds.
ACCESSION U53476
VERSION U53476.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1469)
AUTHORS Bui,T.D., Lako,M., Lejeune,S., Curtis,A.R., Strachan,T., Lindsay,S.
and Harris,A.L.
TITLE Isolation of a full-length human WNT7A gene implicated in limb
development and cell transformation, and mapping to chromosome 3p25
JOURNAL Gene 189 (1), 25-29 (1997)
PUBMED 9161407
REFERENCE 2 (bases 1 to 1469)
AUTHORS Bui,T.D., Lejeune,S. and Harris,A.L.
TITLE Direct Submission
JOURNAL Submitted (03-APR-1996) T.D. Bui, Imperial Cancer Research Fund,
Institute of Molecular Medicine, John Radcliffe Hospital,
Headington, Oxford OX3 9DU, UK
FEATURES Location/Qualifiers
source 1..1469
/db_xref="H-InvDB:HIT000220305"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="ICRFp507A0938"
/tissue_type="brain"
/clone_lib="human fetal brain cDNA library in pSPORT 1
vector, generated by oligo dT priming (from ICRF library
number 507), cloning sites: NotI and SalI"
/dev_stage="17-week embryo"
gene 1..1469
/gene="Wnt7a"
CDS 25..1074
/gene="Wnt7a"
/function="signal patterning"
/note="proto-oncogene; signal transducer"
/codon_start=1
/product="Wnt7a protein"
/protein_id="AAC51319.1"
/translation="MNRKALRCLGHLFLSLGMVCLRIGGFSSVVALGATIICNKIPGL
APRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSR
DGAFTYAIIAAGVAHAITAACTHGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGI
GFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTL
PQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPN
YCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYV
KCNTCSERTEMYTCK"
BASE COUNT 347 a 435 c 416 g 271 t
ORIGIN
1 cacgcgtccg ggccaatcgg gactatgaac cggaaagcgc tgcgctgcct gggccacctc
61 tttctcagcc tgggcatggt ctgcctccgg atcggtggct tctcctcagt ggtagctctg
121 ggcgcaacga tcatctgtaa caagatccca ggcctggctc ccagacagcg ggcgatctgc
181 cagagccggc ccgacgccat catcgtcata ggagaaggct cacaaatggg cctggacgag
241 tgtcagtttc agttccgcaa tggccgctgg aactgctctg cactgggaga gcgcaccgtc
301 ttcgggaagg agctcaaagt ggggagccgg gacggtgcgt tcacctacgc catcattgcc
361 gccggcgtgg cccacgccat cacagctgcc tgtacccatg gcaacctgag cgactgtggc
421 tgcgacaaag agaagcaagg ccagtaccac cgggacgagg gctggaagtg gggtggctgc
481 tctgccgaca tccgctacgg catcggcttc gccaaggtct ttgtggatgc ccgggagatc
541 aagcagaatg cccggactct catgaacttg cacaacaacg aggcaggccg aaagatcctg
601 gaggagaaca tgaagctgga atgtaagtgc cacggcgtgt caggctcgtg caccaccaag
661 acgtgctgga ccacactgcc acagtttcgg gagctgggct acgtgctcaa ggacaagtac
721 aacgaggccg ttcacgtgga gcctgtgcgt gccagccgca acaagcggcc caccttcctg
781 aagatcaaga agccactgtc gtaccgcaag cccatggaca cggacctggt gtacatcgag
841 aagtcgccca actactgcga ggaggacccg gtgaccggca gtgtgggcac ccagggccgc
901 gcctgcaaca agacggctcc ccaggccagc ggctgtgacc tcatgtgctg tgggcgtggc
961 tacaacaccc accagtacgc ccgcgtgtgg cagtgcaact gtaagttcca ctggtgctgc
1021 tatgtcaagt gcaacacgtg cagcgagcgc acggagatgt acacgtgcaa gtgagccccg
1081 tgtgcacacc accctcccgc tgcaagtcag attgctggga ggactggacc gtttccaagc
1141 tgcgggctcc ctggcaggat gctgagcttg tcttttctgc tgaggaaggt acttttcctg
1201 ggtttcctgc aggcatccgt gggggaaaaa aaatctctca gaaccctcaa ctattctgtt
1261 ccacacccaa tgctgctcca ccctccccca gacacagccc aagtccctcc gcggctggag
1321 cgaagccttc tgcagcagga actctggacc cctgggcctc atcacagcaa tatttaacaa
1381 tttattctga taaaaataat attaatttat ttaattaaaa agaattcttc cacctcaaaa
1441 aaaaaaaaaa aaaaaaaaaa aaagggggg
//