LOCUS HSU53346 3125 bp mRNA linear HUM 15-SEP-1996
DEFINITION Human PWP2H protein mRNA, complete cds.
ACCESSION U53346
VERSION U53346.1
KEYWORDS WD40 repeats.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3125)
AUTHORS Yamakawa,K., Gao,D.Q. and Korenberg,J.R.
TITLE A periodic tryptophan protein 2 gene homologue (PWP2H) in the
candidate region of progressive myoclonus epilepsy on 21q22.3
JOURNAL Cytogenet. Cell Genet. 74 (1-2), 140-145 (1996)
PUBMED 8893822
REFERENCE 2 (bases 1 to 3125)
AUTHORS Yamakawa,K., Gao,D. and Korenberg,J.R.
TITLE Direct Submission
JOURNAL Submitted (01-APR-1996) Kazuhiro Yamakawa, Medical Genetics,
Cedars-Sinai Research Institute, 110 George Burns Road, Davis
Building, Suite 2005, Los Angeles, CA 90048-1869, USA
FEATURES Location/Qualifiers
source 1..3125
/db_xref="H-InvDB:HIT000220297"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="21"
/map="21q22.3"
/tissue_type="brain"
/dev_stage="14 week fetus"
/note="trisomy 21"
CDS 25..2784
/note="similar to periodic tryptophan protein 2 (PWP2)"
/codon_start=1
/product="PWP2H protein"
/protein_id="AAB08084.1"
/translation="MKFAYRFSNLLGTVYRRGNLNFTCNGNSVISPVGNRVTVFDLKN
NKSDTLPLATRYNVKCVGLSPDGRLAIIVDEGGDALLVSLVCRSVLHHFHFKGSVHSV
SFSPDGRKFVVTKGNIAQMYHAPGKKREFNAFVLDKTYFGPYDETTCIDWTDDSRCFV
VGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFFESNSLDLYSLSQDGVLCMWQCD
TPPEGLRLKPPAGWKADLLQREEEEEEEEDQEGDRETTIRGKATPAEEEKTGKVKYSR
LAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIA
SVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGG
DDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNF
RTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLC
FNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQ
ITFWDPENAVQTGSIEGRHDLKTGRKELDKITAKHAAKGKAFTALCYSADGHSILAGG
MSKFVCIYHVREQILMKRFEISCNLSLDAMEEFLNRRKMTEFGNLALIDQDAGQEDGV
AIPLPGVRKGDMSSRHFKPEIRVTSLRFSPTGRCWAATTTEGLLIYSLDTRVLFDPFE
LDTSVTPGRVREALRQQDFTRAILMALRLNESKLVQEALEAVPRGEIEVVTSSLPELY
VEKVLEFLASSFEVSRHLEFYLLWTHKLLMLHGQKLKSRAGTLLPVIQFLQKSIQRHL
DDLSKLCSWNHYNMQYALAVSKQRGTKRSLDPLGSEEEAEASEDDSLHLLGGGGRDSE
EEMLA"
BASE COUNT 688 a 845 c 928 g 664 t
ORIGIN
1 tgcggcacac gtgcgacggc cgtgatgaag ttcgcttacc ggttttcaaa tttgctgggt
61 acggtgtacc ggcgtgggaa cctaaatttt acctgcaatg gaaattcagt tatcagtccc
121 gtgggcaata gagtcactgt atttgacctt aaaaacaaca aatctgacac gctgcccctg
181 gccactcggt acaacgtcaa gtgcgtgggg ctgtccccgg atggccgcct cgctatcatc
241 gtcgatgaag ggggcgatgc gctgctggtc agcctggtct gcaggtctgt gctgcaccac
301 ttccacttca agggctctgt gcacagtgtg tccttctccc ctgatggcag gaagtttgtt
361 gtcacaaagg gtaacattgc ccagatgtat catgcccctg ggaagaagcg ggagttcaac
421 gccttcgttc tggacaagac ctattttggg ccctacgatg agaccacctg catcgactgg
481 acggatgact ccaggtgctt tgtggttggg agcaaagaca tgtccacctg ggtgttcgga
541 gccgagcgct gggacaacct catctactat gcactggggg gacataagga tgccatcgtg
601 gcctgcttct ttgaatccaa cagcctggac ctgtactcac tcagccagga cggagtgctg
661 tgcatgtggc agtgtgacac gccccccgag ggcttgcggc tgaagccccc tgcgggctgg
721 aaagcagacc tgttgcagcg ggaggaggaa gaggaggagg aggaggacca ggagggcgac
781 agagagacca ccatccgggg aaaagccact ccggccgagg aggagaagac aggaaaagtg
841 aagtactcac ggctggccaa gtacttcttc aataaagaag gggattttaa caacctgaca
901 gctgcagcat ttcataagaa gtctcacctc ttggtcactg gctttgcttc tggaatcttc
961 catcttcatg agctgccaga gtttaacctc atccactccc tgagcatctc agatcagagc
1021 atcgcctcag tggccatcaa tagctcgggg gactggattg cttttggctg ttcaggcctg
1081 ggccagctgc tggtgtggga gtggcagagt gagtcctacg tgctcaagca gcagggccac
1141 ttcaacagca tggtggccct ggcctactcg cccgacggac agtacatcgt gactggcggg
1201 gacgacggca aggtcaaggt gtggaacacc ctcagcggct tctgcttcgt cacttttacg
1261 gagcactcca gcggggtgac cggtgtgacc tttactgcca ccggctacgt tgtggtgacc
1321 tcatccatgg acgggaccgt gcgagccttt gaccttcaca ggtaccgaaa cttccgcacc
1381 ttcacctctc cacgccccac ccagttctcc tgtgtggcgg tggatgcgag cggtgagatc
1441 gtctctgcag gggcgcagga ctcctttgag attttcgtgt ggtccatgca gacaggcagg
1501 ctccttgatg ttttgtctgg acacgaaggg cccatcagtg gtctgtgttt taacccaatg
1561 aagtccgtcc tggccagtgc ctcctgggac aagacggtgc gcctatggga catgtttgac
1621 agctggagga ccaaggagac gctggccctg acctctgatg ctctggctgt gacttttcgc
1681 cctgatggtg cggagctggc tgtggccaca ctgaactcac agatcacctt ctgggaccct
1741 gagaacgcgg tgcagacggg ctccattgag ggcaggcatg acctcaagac tggcaggaag
1801 gagctggaca agattacagc caagcacgcg gccaagggga aggccttcac cgccctgtgc
1861 tactctgcag acggccacag catcctggcg ggaggcatgt ccaagttcgt gtgcatctac
1921 cacgtccgtg agcagattct catgaagagg ttcgagatct cttgcaacct gtctctggac
1981 gccatggagg aatttttgaa ccgaagaaaa atgacagagt ttggcaacct ggcactaatt
2041 gatcaggatg ctgggcagga ggatggagtc gcgataccac tgccaggcgt caggaaaggt
2101 gacatgagtt ctcggcactt caaacctgag atcagggtga cctcactccg cttctctccc
2161 actgggcgct gctgggcggc caccaccacg gagggactcc tcatctactc cctggacacc
2221 cgcgtgctct ttgacccgtt tgagctggac accagcgtca cccccgggag ggtgcgcgag
2281 gcactgcgcc agcaggactt caccagggcc atcctcatgg ccctccggct caacgagagc
2341 aaactggtgc aggaggccct ggaggcggtg cccaggggcg agattgaagt ggtcacctcc
2401 tcccttcctg aactgtatgt ggagaaagtg ctggagtttt tagcttcctc ctttgaagtg
2461 tctcgccacc tggaattcta cctcctctgg actcacaaac tgctcatgtt gcacggacag
2521 aagctgaagt ccagagccgg gacgctgctg cctgtcattc agttcctcca gaagagcatc
2581 cagcggcacc tggacgacct gtcgaaactc tgtagctgga accactataa catgcagtac
2641 gcactagcag tttccaagca gcggggcaca aaacgctccc tagacccgct gggaagtgag
2701 gaggaggcag aagcatctga agatgacagc ctgcatctgc ttggaggagg aggcagagac
2761 tcagaagaag agatgctggc ctagagccag ccggttgcag cgttggattg tgccggctaa
2821 gacctgccag ggagatggga cccttgtgcc acctgggcca gcaaagagga ggggtccaga
2881 gaacagctga aatactgtca ctagtggtag tgacttgctt ttcctgtgca cacatgtagc
2941 ccatcaggac agcgagccga cgggtcacgc caggggccgg cacgcactgg cacctggccc
3001 caggagcggg gccgtgtgaa cggtgatgaa tgttgaaaat gcgtctcaga gaggtattca
3061 catgaacttt gtatgagact tatttatatt tttaacataa aggtttgata aagaacttag
3121 ggatt
//