LOCUS HSU52840 8056 bp mRNA linear HUM 02-APR-1998
DEFINITION Homo sapiens semaphorin F homolog mRNA, complete cds.
ACCESSION U52840
VERSION U52840.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8056)
AUTHORS Simmons,A.D., Overhauser,J. and Lovett,M.
TITLE Isolation of cDNAs from the Cri-du-chat critical region by direct
screening of a chromosome 5-specific cDNA library
JOURNAL Genome Res. 7 (2), 118-127 (1997)
PUBMED 9049630
REFERENCE 2 (bases 1 to 8056)
AUTHORS Simmons,A.D., Puschel,A.W., McPherson,J.D., Overhauser,J. and
Lovett,M.
TITLE Molecular cloning and mapping of human semaphorin F from the
Cri-du-chat candidate interval
JOURNAL Biochem. Biophys. Res. Commun. 242 (3), 685-691 (1998)
PUBMED 9464278
REFERENCE 3 (bases 1 to 8056)
AUTHORS Lovett,M., Simmons,A.D. and Overhauser,J.
TITLE Direct Submission
JOURNAL Submitted (27-MAR-1996) Biochemistry and the McDermott Center,
University of Texas Southwestern Medical Center, 5323 Harry Hines
Boulevard, Dallas, TX 75235-8591, USA
REFERENCE 4 (bases 1 to 8056)
AUTHORS Simmons,A.
TITLE Direct Submission
JOURNAL Submitted (14-JAN-1998) Otorhinolaryngology and the McDermott
Center, University of Texas Southwestern Medical Center, 5323 Harry
Hines Boulevard, Dallas, TX 75235-8591, USA
REMARK Nucleotide and amino acid sequence updated by submitter
COMMENT On Jan 16, 1998 this sequence version replaced gi:1354463.
FEATURES Location/Qualifiers
source 1..8056
/db_xref="H-InvDB:HIT000220283"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5p15.2"
/clone="CSA1"
CDS 638..3862
/note="Cri-du-chat region"
/codon_start=1
/product="semaphorin F homolog"
/protein_id="AAC09473.1"
/translation="MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIG
PWLREFRAKNAADFSQLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKK
ACYSKGKSKEECQNYIRVLLVGGDRLFTCGTNAFTPVCTNRSLSNLAEIHDQISGMAR
CPYSPQHNSTALLTAGGELYAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPN
FVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARL
NCSRPGEVPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGP
FKYQENSRSAWLPYPNPNPHFQCGTVDQGLYVNLTERNLQDAQKFILVHEVVQPVTTV
PSFMEDNSRFSHVAVDVVQGREALVHIIYLATDYGTIKKVRVPLNQTSSSCLLEEIEL
FPERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDV
VMKKCTSLEESLSMTQWEQSISACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCR
TRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSN
PTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWGPWERCTAQCGGGIQARRRICEN
GPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISDNGDHYEQRFRYTCKARLADP
NLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSR
DCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNTLPCPVDGVWSCWSPWTKCSAT
CGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWSEWSDWSECEASGVQ
VRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEEKRCGEFNMFHMI
AVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITNHINKLDKYDS
VEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY"
misc_feature 2767..2820
/note="encodes type I thrombospondin repeat; similar to
Swiss-Prot Accession Number P07996"
misc_feature 2824..2877
/note="encodes type I thrombospondin repeat; similar to
Swiss-Prot Accession Number P07996"
repeat_region 7766..8055
/note="Alu"
BASE COUNT 1957 a 2055 c 1970 g 2074 t
ORIGIN
1 ctgctctccc tgagcccgct cccgagcgct gctttcccgc cgcgggtggg cttcgcagcc
61 tcaggccagc cgcggccctt ggcccgctgc agccccggcc ctccaccttc cccgtgcagg
121 ggcggcccgg ccagtgtcgc tcatcccggg acgctccctt ctcccaccca ggactgcccc
181 gcggagctgg cttggacacc caactttgcc acctcgaggg tcgtctctgc tgggcgcgaa
241 cctgcccacc caccggttgg ccgcgcgctc ggggaccgtg ctcgtggccc ccaagccggt
301 gcccccattc tggaactcag cgagtagggg gcggctctgg ggaagtggca gggggcggct
361 gcagctgctg cctccacttc cctagccagg tgctgaagag gatcctcgga gccgctctgg
421 cccccaggcg ctggatgact ggcaccagcg ctcctcgcac ctgtgttggt gtgtgagact
481 tgggctggag tgcccacgtg gctgtggagt cagtgtgatt catgattgag gaaacgcgtc
541 ctccatcctc tctctccttg gcactttcca cacatgagga gaagaagagc ttctgtttag
601 aagacacgtg cccagagtca gaggcccctt gcccaccatg aagggaacct gtgttatagc
661 atggctgttc tcaagcctgg ggctgtggag actcgcccac ccagaggccc agggtacgac
721 tcagtgccag agaaccgagc atccagtcat ctcctataaa gaaattggcc cctggttacg
781 ggagttcaga gcgaagaatg ctgcggattt ctcgcagtta acatttgacc caggacagaa
841 agaacttgtt gtaggagcaa gaaactacct cttcaggtta cagcttgagg atctgtctct
901 tatccaggct gtggaatggg agtgtgatga agctaccaaa aaggcctgtt acagcaaagg
961 caaatcaaag gaggaatgtc agaactacat ccgggtgctt ctggtgggtg gcgaccggtt
1021 attcacctgt gggaccaatg cattcacgcc tgtctgcacc aaccgctcgt tgagcaacct
1081 ggctgagatc catgatcaga tcagtggcat ggcccgctgt ccctacagtc cccagcacaa
1141 ttccacagcg ctcctcacag ctggtgggga gctctatgct gctacagcca tggattttcc
1201 aggacgtgat cctgccattt accgaagcct aggcatttta cctcctctcc gcacggcgca
1261 gtacaactcc aaatggctca atgagccaaa ctttgtgtca tcttatgaca tcggaaattt
1321 tacctacttc tttttccgag aaaatgcagt agagcatgac tgtgggaaaa cagtgttctc
1381 cagagctgcc cgggtgtgca agaacgatat tggtgggcgc ttcctgctgg aagacacctg
1441 gaccacattc atgaaggctc gcctgaactg ctcccgtcct ggggaagtcc ccttttacta
1501 caacgaattg cagagtactt tcttcctgcc tgagctggat ttgatctatg gcatctttac
1561 caccaatgtg aacagcattg cggcctcagc tgtgtgcgtc ttcaacctga gcgccatcgc
1621 gcaggccttc tctgggccct tcaagtacca agaaaactcg cgctcggcct ggctaccgta
1681 tcccaaccca aacccccact tccagtgtgg caccgtggac cagggcctgt acgtgaacct
1741 gaccgagaga aatctgcagg atgctcagaa gttcattctg gtgcatgagg tggtacagcc
1801 agtgaccaca gtgccctcct tcatggagga caatagccgc ttttcccacg tggcagtcga
1861 cgtggtgcag ggcagagaag cgctcgtcca catcatctat ttggccacag attacggaac
1921 cattaagaaa gtgcgggtac ccctgaatca gacctcaagc agctgtttgc tggaagagat
1981 tgagctcttc cctgagaggc ggagggagcc catcaggagc ctgcagatcc tgcacagcca
2041 gagtgtcctg ttcgtggggc tgcgggagca cgtggtcaag atccccctga agaggtgcca
2101 gttctaccgc acacgcagca cctgcattgg ggcccaggac ccttactgtg gctgggatgt
2161 ggtaatgaag aaatgcacaa gcctggagga gagcctgagc atgacgcagt gggaacagag
2221 catctctgcg tgtccgacca ggaatctcac cgtggatggg cactttggtg tgtggtctcc
2281 gtggacgcct tgcacgcaca cagatggcag cgccgtggga tcctgcctct gtcgaacccg
2341 ctcctgcgac agcccggccc cgcagtgtgg tggctggcag tgcgagggcc ctggcatgga
2401 gatcgccaac tgttccagga acggaggctg gactccctgg acctcgtggt ctccctgcag
2461 cactacctgt gggatcggct tccaggtgcg gcagcgctcc tgcagcaacc ccactcccag
2521 gcacgggggc cgggtgtgcg tgggacagaa ccgcgaggaa agatactgca atgaacattt
2581 gctatgtccc ccacacatgt tctggacagg ctggggtcct tgggaacggt gcacagccca
2641 atgcgggggt ggcattcaag ctcgccgcag gatctgtgag aatgggcctg actgtgcagg
2701 ctgcaatgtg gagtaccagt cttgcaacac caacccgtgt cctgagctga agaagaccac
2761 gccctggaca ccctggacac ctgtcaacat ctctgacaac ggcgaccact atgagcaacg
2821 attccgatac acatgcaaag cccgcctggc tgatccgaat ttgctggaag tgggaagaca
2881 gagaatcgaa atgcggtact gttctagcga cggcaccagt ggctgctcca cagatgggct
2941 ttctggggat ttcctgcgtg ctgggagata ctctgcccac acggtcaacg gggcttggtc
3001 agcctggacg tcgtggtcac agtgcagccg tgactgcagc aggggcattc ggaaccggaa
3061 gcgtgtttgc aacaaccccg aacccaagta tgggggaatg ccttgccttg gcccatctct
3121 ggaataccag gaatgcaaca ctttgccctg cccagtggat ggcgtgtggt cttgctggtc
3181 cccctggaca aaatgttcag caacatgcgg cggtggacac tatatgagga cccgctcttg
3241 ctccaatcca gccccggcct atggagggga catctgcctg gggctgcaca cagaagaggc
3301 actctgcaac acgcagccct gcccagagag ctggtcggag tggtcggact ggtctgagtg
3361 tgaagcctct ggcgtccaag tccgcgcccg ccagtgcatc ctcctgttcc ccatgggcag
3421 ccagtgctcc gggaacacca cggagagccg gccgtgtgtg tttgactcta atttcatccc
3481 agaagtatct gtggcaagat ccagtagcgt agaagagaaa aggtgtggag agttcaacat
3541 gttccacatg atcgccgtgg ggctgagcag ctccatcctc ggctgcctcc tcaccctgct
3601 cgtctatact tactgccagc ggtaccagca gcaatcccac gatgcgactg tcatccaccc
3661 cgtctcacct gcccccctta ataccagcat aaccaaccac atcaacaaac tggacaagta
3721 cgactcggtg gaggccatca aggcatttaa caaaaacaac ttgatcctag aggaaagaaa
3781 caaatacttc aacccacatc tcactgggaa gacctattct aatgcctact ttacagatct
3841 caataattat gatgagtact aacagctttc atgttttggg cttcttgtaa atccccagtt
3901 cctcaaggcc tgtgccccat gactgcccat gtttctgagg cttcagagtc gaagtttgga
3961 tacatttcaa gtgcatttca agccaccaga gtgtcccatt ggtgccaaaa atacacgtct
4021 ttaaaagcaa caaaaattga aataagacat cgtgaaaatc ttgaccattg ttgattgagc
4081 cagggtggtg aagtttttaa ttggtgttca tcctattttt ctgacaagtc cattggtttg
4141 ttttttgagc attattttat aaatgtgcca cccacattgg aaggagtctt tctttagaac
4201 tttggagtgt aaatcttcat gatgttgtaa attcaagaaa ataggcactt tctctgaaag
4261 acctgctcct tccacaagaa gtgcataggt ccataatatt tcataaaatg aagaaaaaga
4321 atgtggccaa acaattattc accatggatt gcccaacttt ccaaatctgg ataaagctgt
4381 gggattcttg gaagcagctt gagtgttttc atcttgcctg ggaagcccag gaattccacc
4441 tggtccacac cggcagaagt tacagtagac tgtgaggcac cccaccttgc tcctgatgca
4501 gtttctgtgc cattgctggt gctggtggag gcagcggagc agaggctcag gcacaatgaa
4561 gcgtggatgt gttctgcagg ttgctgcaaa actcacctta ttctgacttt tggatttcat
4621 ggcattccag gaagctcctt gccatgctgt tggcctggaa gtccacctgt ctggtccata
4681 gtgacgtcct gaagagccag tctgtaaaat aaccaaccac ttacttagcg tttggataga
4741 ctccatgcct tctctctccc tgcaaagaaa aatcttgaac atttatgatg tcaattagtg
4801 aaagtattga aaatactaaa ttataactaa aagcaacttt ttatgttatt gaaaatattg
4861 aaagaactga tattaatgat aatcatttta tttttcatct ctctgatata cccaatgtgt
4921 ggcaatcagc ccctaccatg agcattaatg ccatgtaaag ctggctttct ggagtctgcc
4981 aggtccacac gaagtgctac ccccagtttc tgctgttact tgctgcctcc aggccagggg
5041 agcaggagat gctcagctct ggtgcctttt cttttatttc agtgctgcct tcccacccac
5101 ccagtccatt caccctcacc tctccctgca tggaggcaac agcatttcca agatgtacct
5161 tgggaagtca ggatagctgg aagtaagggt ttttggggat ccctgtggtc tcttcactga
5221 tcatcgataa gcatttaaga gtgtgctaac accattcaca gaggtccctg gaaaaaaata
5281 tataattttc tcacaaacaa ccaatacata acctatggca gttggttgaa taattattga
5341 aaaaaagaac acgactgaaa aagttcatct gatgcctctg agcatgtgat aaagtcctgg
5401 gtagacatgg aaacgtgttc ttacaaatga accttcggat ctatgaaaga aaatatagta
5461 gggggactaa ggaacataga attttattag catatgtgat tttaccctta tctttgtttc
5521 taatttaaag aaacaatttc agaaagtgtt agaagaattc tatgtttaat aatgaatatt
5581 gttgagttca aaatattctc atatacccag atttacagag atgacacagt attgaaatgg
5641 caggtgggct ctgtaagtta tttggggatt aatgaaatcc agggtcttgg caggggggac
5701 tcaatgtggc cctctcactc atccctcata tgtcaagagt ccttcctgtc ttatatgcac
5761 atgctccaag gtccatactc agtaggggga aatctagccg gatggttccc caattgttcc
5821 tcggctggat tttcatcatc agaaatttcc aactcatctc atcagttttc ttgtaagaaa
5881 aaaacatttt tcactttgta gcacaatttt agttattttt gagtcttctt ccctaatagt
5941 ttgtaagctt aaagggacaa ttttaatttt cccctggtta aagagggatt ctaatatttc
6001 caagaatgtt ttccactgga attgatggga aatggtttct aaatggcatc gaagctggtc
6061 tttaatgatc ttttgcaatg acttgggaaa aacaccctcc ctcactacag gatcttcatg
6121 ttgttaataa tataaacaaa cctttgaaat tagcattgca aaagaatccc atttttgttt
6181 cgtaccacac tgttcaaagg aaaattgttt atctctcttc ctttctctct ctctcttatt
6241 tgacagaata gcaagtgttt agataatttc agatatattc ctaagtattt taccagctgt
6301 ggaataagtt gtgtttgtcc atcactgtgt agctaccgtt cacatgttct ggctctgtac
6361 tccacgctta tcgcgtgaac cctcacatgt tggactttca cagtgtgatc tctcacctgt
6421 cttggaaact ccttcataaa gccgctcttc cttaggcctg ggctgtttgg aagtcctggt
6481 gaaactttgc ggttcacatt ttaaattcct gaatgacctt ttcattctct ctttctttat
6541 ctttgttttt gtccttcatt ccctcctttt gttcttcctt cctgcctttc acgtcaccta
6601 cttatccgac tatttcctcc atttgcttct tttctatttg ccatcacctg tgacccgagt
6661 ggaacaaaaa ccaacacata gttttaagct acacctttct gcacctgatg taaaatgaca
6721 ttaatccact atttaacttc taaaattatt tctgaataca gttgcagata ggctggtttt
6781 catgaggaag ctcgcttggc tttagtctta catttaaatt ctttgaaagt ggctcccagt
6841 gctattcagg gtcctttctt gaggccagac tcatcaccat ctactattga ttttacagtg
6901 cactgacagt ttacaggaag gagaagaaca gaatttctgc acactacaca acatgtgggc
6961 ttcctgtagc tccagggaca tgtagctttg gtgaaactgg ggttttgtaa cctctgaatg
7021 atatggactt agtgaattct aaggaactca gggggcacgt ggtcaggctc caccgcacag
7081 aagagccaca gtctccagac tcatggcgtt ccctccagaa ctccccattc ccctctgagc
7141 atatttctat gctgctgctt cttgtgactt acatgaggca tctcagcttc ttcatgtttg
7201 tagggatggt tccctaagcc tgttcaagta ggctctcact agagttacca ttcatatttg
7261 agaagaaaag aacatttatt aaatgtatgt gtggggctga ggttctaaag gaattgaaaa
7321 gagacgataa acattgaatg agggtgaggg catccctgct ggggagaaac ctctgtcccc
7381 taggaagagt ccgttcatgt catgtggttt gggatgaacc aggggtctgc ccccatcggg
7441 tcacaggtga tgccaaatag aaaagaagca aatggaggaa atagtcggat aagtaggtga
7501 cgtgaaaggc aggacctggt caccccagca agtgctatgg acagttcccg gaaacggttg
7561 cccacttcac aggtccatgg gtctgaccct tggactctgc caggatcaac tgcccagagt
7621 gccagagttt tagccaaagg tgtacttact tccttattta tctccaaaag gatggaaact
7681 gtgggagtca aagcctattt tgctgagtgt tcccactgga tcctctgtag aattagcagg
7741 tcatgctgtc aaaatcatgg acaaaggctg ggtgcagtgg ctcatgccta taatcccagc
7801 actttgggag gccaaggtgg gcggatcacc tgagctcagg agtttaagac cagcctgggc
7861 aacatgggga aactccatct ctacaaaata tacaaaatat tagccagcca tcgtggtgcg
7921 tgcctgtggt cccagtttct tgggaggctg aggcgggagt atcatttgag ccaggaggtt
7981 gaggttgcag tgagctgaga tcacatcact gcactccatc ctgggtgaca gagagagacc
8041 ctgtctcaaa aaaaaa
//