LOCUS HSU52153 2598 bp mRNA linear HUM 21-MAY-2001
DEFINITION Human inwardly rectifying potassium channel Kir3.2 mRNA, complete
cds.
ACCESSION U52153
VERSION U52153.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2598)
AUTHORS Schoots,O. and Van Tol,H.H.M.
TITLE Cloning of cDNAs for four inwardly rectifying potassium channels
from human
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2598)
AUTHORS Schoots,O.
TITLE Direct Submission
JOURNAL Submitted (25-MAR-1996) Oscar Schoots, Molecular Neurobiology,
Clarke Institute of Psychiatry, 250 College Street, Toronto, ON M5T
1R8, Canada
REFERENCE 3 (bases 1 to 2598)
AUTHORS Schoots,O., Wilson,J.M., Ethier,N., Bigras,E., Hebert,T.E. and Van
Tol,H.H.
TITLE Co-expression of human Kir3 subunits can yield channels with
different functional properties
JOURNAL Cell. Signal. 11 (12), 871-883 (1999)
PUBMED 10659995
FEATURES Location/Qualifiers
source 1..2598
/db_xref="H-InvDB:HIT000220248"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="cerebellum"
/clone_lib="Clontech #HL1128a"
CDS 652..1923
/note="GIRK2"
/codon_start=1
/product="inwardly rectifying potassium channel Kir3.2"
/protein_id="AAB07044.1"
/translation="MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHI
SRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTV
TWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVI
TDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKL
CLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSP
LIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGY
RFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQH
AELETEEEEKNLEEQTERNGDVANLENESKV"
BASE COUNT 684 a 643 c 601 g 670 t
ORIGIN
1 aaagctaaat agccatacag cagctctgac aatgttgtgc tggatattgc agtttgcttt
61 caaggtgcag atgtaaggat ttaaaaaaat aataatttgg caccaaataa atatgagtag
121 cattcattga atctgcggat ttcatgacgt ctctctgcgt ggtccaccac ttttctccta
181 accggggatt tttttttttc ttctgccact cttatctttc cccacttcat tccacccagt
241 ctccctcccc cgtccctgcc caaacgcgcg cccctccgcc cctcccttgg gcccagcgcc
301 cagccctgct ctccgcgctc ggccagaggg agccagtccg gagacggccg cacctggctg
361 gagaggctgg gcgggcggag gggtggagac ccgcggacgc cgggaagccg gacctggagc
421 cggagcagcc gcgagcagaa tggagtctcc taacagcctc tcggtgctga tgtgaaattt
481 gaccatctga ttccagtttt tttcttttcc ttttcttttt tgcatttcct tccctcgcca
541 tccgtcgtgt agtgaattgt tcagtcttgc tccgtttcaa gagaggagat catgattgag
601 tgaagccacc ccgtccgcag ccaggaaaag cacaaagaag aaactgcaac aatggccaag
661 ctgacagaat ccatgactaa cgtcctggag ggcgactcca tggatcagga cgtcgaaagc
721 ccagtggcca ttcaccagcc aaagttgcct aagcaggcca gggatgacct gccaagacac
781 atcagccgag atcggaccaa aaggaaaatc cagaggtacg tgaggaaaga cggaaagtgc
841 aatgttcatc acggcaacgt gagggagacc tatcgctacc tgaccgatat cttcaccaca
901 ttagtggacc tgaagtggag attcaaccta ttgatttttg tcatggttta cacagtgacc
961 tggctctttt ttggaatgat ctggtggttg atcgcataca tacggggaga catggaccac
1021 atagaggacc cctcctggac tccttgtgtt accaacctca acgggttcgt ctctgctttt
1081 ttattctcaa tagagacaga aaccaccatt ggttatggct accgggtcat cacagataaa
1141 tgcccggagg gaattattct tctcttaatc caatctgtgt tggggtccat tgtcaatgca
1201 ttcatggtgg gatgcatgtt tgtaaaaatc tctcaaccca agaagagggc agagaccctg
1261 gtcttttcca cccatgcagt gatctccatg cgggatggga aactgtgcct gatgttccgg
1321 gtaggggacc ttaggaattc ccacattgtg gaggcttcca tcagagccaa gttgatcaaa
1381 tccaaacaga cctcggaggg ggagttcatc ccgttgaacc agacggatat caacgtaggg
1441 tattacacgg gggatgaccg tctgtttctg gtgtcaccgc tgatcattag ccatgaaatt
1501 aaccaacaga gtcctttctg ggagatctcc aaagcccagc tgcccaaaga ggaactggaa
1561 attgtggtca tcctagaagg aatggtggaa gccacaggga tgacatgcca agctcgaagc
1621 tcctacatca ccagtgagat cctgtggggt taccggttca cacctgtcct gaccctggag
1681 gatgggttct acgaagttga ctacaacagc ttccatgaga cctatgagac cagcacccca
1741 tcccttagtg ccaaagagct ggccgagtta gccagcaggg cagagctgcc cctgagttgg
1801 tctgtatcca gcaaactcaa ccaacatgca gaactggaga ctgaagagga agaaaagaac
1861 ctcgaagagc aaacagaaag aaatggtgat gtggcaaacc tggagaatga atccaaagtt
1921 tagtgcccta gctgggcaaa cccttctctt ctccccccaa cacaatcttt ccttgtctct
1981 cattctcttt ctttttctgt ctctcttgct ttgttcttta tttgtttata tttaattttt
2041 acatgaccag aaaacaaatc ttcaaggtgt aaaatatcta cctgccctct ctcagttatt
2101 cagattgaca aggtagacat ggatttgatg aaagtgcaaa gtgccctcat ttgtggccca
2161 agcctggtct cctcccaaaa tactacacat ccaactcctg gagatttcag ttacttacct
2221 gcatgtgttg tacaatacca gatcactcaa aaaggtgtgt caaagatttt acctgggata
2281 tgacaagcaa ggtttctggt gcctatttat tcattcagtg agacacagag tggagccctc
2341 agttttatgg atcccaattc atttcatcta ctacagggtg aggtgcttgc ccccatgtgg
2401 gtgtggcagt tacagggccc aggtgagctg aagacaaacc actgtacata tatatgcctt
2461 atgtaattat tttctttttg taattagtaa taaaacccag catgtacaaa agtaccatag
2521 cacagcactg ctaaatactg tacatagatg tatcattaat gtaggtttag atatataact
2581 ttagaaataa gaagcaaa
//