LOCUS HSU51899 9844 bp DNA linear HUM 23-OCT-1996
DEFINITION Human kappa-casein gene, complete cds.
ACCESSION U51899
VERSION U51899.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 9844)
AUTHORS Edlund,A., Johansson,T., Leidvik,B. and Hansson,L.
TITLE Structure of the human kappa-casein gene
JOURNAL Gene 174 (1), 65-69 (1996)
PUBMED 8863730
REFERENCE 2 (bases 1 to 9844)
AUTHORS Edlund,A.
TITLE Direct Submission
JOURNAL Submitted (20-MAR-1996) Anders Edlund, Astra Hassle, Molecular
Biology, Tvistevagen 48, Umea S-907 36, Sweden
FEATURES Location/Qualifiers
source 1..9844
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
regulatory 330..336
/regulatory_class="TATA_box"
mRNA join(362..425,2572..2633,5576..5608,6755..7250,9018..9182)
/product="kappa-casein"
exon 362..425
/number=1
intron 426..2571
/number=1
exon 2572..2633
/number=2
CDS join(2580..2633,5576..5608,6755..7216)
/codon_start=1
/product="kappa-casein"
/protein_id="AAC50772.1"
/translation="MKSFLLVVNALALTLPFLAVEVQNQKQPACHENDERPFYQKTAP
YVPMYYVPNSYPYYGTNLYQRRPAIAINNPYVPRTYYANPAVVRPHAQIPQRQYLPNS
HPPTVVRLPNLHPSFIAIPPKKIQDKIIIPTINTIATVEPTPAPATEPTVDSVVTPEA
FSESIITSTPETTTVAVTPPTA"
intron 2634..5575
/number=2
exon 5576..5608
/number=3
intron 5609..6754
/number=3
exon 6755..7250
/number=4
intron 7251..9017
/number=4
exon 9018..9182
/number=5
BASE COUNT 3308 a 1750 c 1429 g 3357 t
ORIGIN
1 aagctttatg agtgatgact ctacatcctt ctctgcattt cttttttatt ttattttatt
61 ttattttatt ttattttatt tttattatac tttaagtttt agggtacatg tgcacattgt
121 gcaggttagt tacatatgta tacatgtgcc atgctggtgc actgcaccca ctaactcgtc
181 atctagcatt aggtatatct cccaatgcta tccctcccca ctccccccac cccaccacag
241 actgacccaa aggtgaccct gctatcatca tcttattggg taaaaagtag gagggaaata
301 gaatagcgtg actcaaggta ctaataccct ttaattggtc ttcagttatt tttcttgggt
361 cttctctaca gctgacaggc caactcaacc tactgccaac caagacctga ctggcacgag
421 gaaaggtaat gctgctgaaa cacttggaga aagtgatcct tttcacagta gttagttggg
481 acatcaccat agttatttca gaatcacatt ttcttccttt tagttattgt taagtttgaa
541 tatgacctag catcacttta aaattaattt ctaacctaaa cctaagttct ggatggtgtt
601 atgttcaaat ttatttttaa ctttactttg ggttccagtc aaattctgat accaactaaa
661 tcatagcagc cattgtgaat tccgaacaag aaggcgttta acgtattcct acagacaaat
721 gttgagagtt aactctacag gaagttgggc tcatgataat aatcgcaatt aaccccttaa
781 ttactttcaa attttatttc tataaaagtc ataattttat ttgttatgga ataattattt
841 ttttaaaaca tgtttttcaa atattcatga aagctggata attctaccat ttcacgaatt
901 atttcttctt accaagtgat gagggcaaat gcaaatgtag ctgatacgca aagtatggtc
961 ttatctctgt gatttttgtt tgtgccaaaa ggaaattact atcattttat agaatatttt
1021 cttttgttta catatcattt tactgtgtga actgataagg ggtctgtgat tcatcataaa
1081 aacattttca gtctataatc ctaaaagatc actagcaagt gaagcattaa taaggagctt
1141 catcccactt aaagaaatat gagtgtgctt agattgttca aattgattcc aaatgagttc
1201 catcaaatgg aaatttgatg acatcgtatg ggcagttttg aagtcacttt agtagacagc
1261 cttcctaatc attattgcct gagaatcaga cgctaatgga gtccagtggg ctttccatcc
1321 cctatctgag gctttaattc tgtgaatctt ttttgcgaag ttcaactttg tagtgattca
1381 agtttatatg agtgtgtcaa taacaatagc tgcaacaaga tgaagttagt aattacttcc
1441 taaacataat atatacttaa atataaaaag tttggggtat catatattat tagtctaaaa
1501 agatgattta ttaaaaatca aataagcaag tatgacactg tatatactct tttagaaaaa
1561 taaggctaat gtatttcttt aaatatttta gtcaaagcca ctgtaattgt catctctata
1621 cttcttatta aaacaatcaa gttaatcata tcagttatga ttactggaga agtatgttat
1681 aaagaaaaca gtctcataac cctccacttc ccattccatc ctacatactt ctgttggatt
1741 gatcatggaa ttatagaatt ttagaaatct ctaagttcaa accctggttt tacaggtaag
1801 aaaatgtaaa gcccaggaaa gggaaatcac ttgatcaaag ttacagaggt agagataagg
1861 cctggtctag aattcagtcc tccaaaaaat gtatagtcat acactttcta gtccaaaaac
1921 actcaattgt tttctgttgt ttataaagcc atgcctagct ttttaaccca tcattatctt
1981 aaaggtgtct actttttctg ctctaaactt tccttccaat cttatatttc ccttctcata
2041 caagattcca atcaaatgtt catggcgatt ctcaagactt tctcctctac ttgaaatatt
2101 tctctccctg ttaaatactg cataggcaag cctcatctat atgtcatttt ttccacacaa
2161 agactgctgc ttctcttaac tgaaactttt attaatagaa aaccactttt gtggcatttt
2221 ctactttttt tccctcttac agttgttttt cagtatatgt ttcaacactc ttcctaaaat
2281 tgatgctact cattggcaag gcctgtatca tatttacatt gataatctca acatttgaca
2341 tagtaatgat aatttgataa ttccgttaat attgtcaaaa attaaattca gaaattttta
2401 ctccaagttt gagtttttac attcttttgt taaaataaat ttttcacatc ggctaaatct
2461 acctgtaaat ctggcttttt ttcttaatca aggaaacatt gtattcaagt cactcctaaa
2521 tttctagtaa caaattcttt taaattaatt tttttttaaa tttatcttta ggtgcaataa
2581 tgaagagttt tcttctagtt gtcaatgccc tggcattaac cctgcctttt ttggtaagtt
2641 aatttcatct aaccagattg tactgacttt aagaaaattt tgtttaaggg ctttaactat
2701 gcaaacttct aaatacaatt atgcttcata gaacaaaata tccacatagt tgttacattt
2761 ttaaggttaa tttttttaat atttatttct attatgaaat caaagtcatg ttcttttgga
2821 tatccattta gttctgtgaa ttaagaaatc acacttaatc atgtacagga aacttttaaa
2881 attctcatgc tatagagaaa atacattcag gggaaaaaca atactgaaaa cattttaaaa
2941 ttgtaaatgc attaaggata attcagaaag aataaataca gaaatcatag tctgggaatc
3001 agaaattatt ttaattaagt tcctgtctca cccagactcc aatctcttta tggaaacaaa
3061 atccttcaaa ggtcaacttt ggttaagctt tttcacaagt ttcaaagacc ttgatacttc
3121 tgcctttaat atttgaatca ttaacttttg ttatattctt ccccattatg tcaattgact
3181 gacccctttc cagggatcaa tggttataaa cagcttgaag gcttgcaggc attatcttga
3241 attatatgca atgttttaag gctactggac ttagaaaaag gttctgtttt tttcttttaa
3301 ttttttgact tgtttttatt gttgttttgg ctattgcctc tttttatttt cttgttcatc
3361 tgggtattct aggcactgac aaaggaggca agcataaata atggtatatg tcctcctcct
3421 agattgtaaa attttgaagg aacactagtc ctcgttctgt gaatctctgt aatatttatt
3481 tattattaag tttagagttg cttttaagtt aacatctatt aattaattct attacctgca
3541 tgttgtgctt gtgtataaca tgtccattaa ttctattagg tcaattcttg gagtcaaaat
3601 taccttttaa aactttgagt tctacaactc aatactttgt ggtcacctga acatttggaa
3661 cttaggttgt ctctttgagt aatagggctt aaagtttaaa tcatgaaatg atctacaaat
3721 ccctgctgca tagcaacctc ttcctgagct acctgagccg gattcgcttt caaacattcc
3781 ttcccatttt cacaaaggct tcaggcctca gggacatgaa caaatataca gaaaaaaaaa
3841 aatttattga ttttaccatt caatcttatg agtagtcaaa tttatacaaa ttaaaacatc
3901 aatgtgatac catgttatat gtactatttt atcccttccc ccaaaataaa aatagttaga
3961 taatatttta ctagcactta tgcactaaac tgcataaaca catagcctat tggtgacatt
4021 ataatttgac acaacttttc tataccacaa tttcataatt tctatcaaag aatcaaatct
4081 catttgtgaa aaatcatttt aaggtattaa cgaaaattat taaaaaggcc actggtatac
4141 agatgttaat catcactctg tttataatta aaattttatc ttaatagata acgataagaa
4201 ataaacattt catgacataa tcattgatca cttagttatc aactataaaa atgtaactat
4261 gaacctatga tataaataaa aaaaagagac accacatttc ctataaaaag caggatactt
4321 tttagacaag catataccag gaatacataa cataggttga tatcgcatta aggtatctag
4381 attgtcagaa ttttttaaag tatactttct acaatattca tattacttct tttttttttt
4441 tttttttgag acagagtctc gcttggtcgc ccaggttgga gtgcagtggc acaatcttgg
4501 cttactgcaa cctctgcttc ccaggtttaa gcgattttcc tgcctcagcc tcccaagtag
4561 ctgggactac aagtgcccgc caccatgccc agctaatttt tgtattttta gtagaggcag
4621 ggtttcacca tgttggccag gctggtcttg aacccctgac ctcagatgat ccacccacct
4681 ctgcctccca aagtgctggg attacagggt gagacatgtg cccggcctca tattacttct
4741 ttacatttta aactaatgat ttaatatatt taaagaaaag caagtctttg tctcaaagca
4801 aggaaacttt attaccttct caattttctg attttctata ctcacacctt ccaaaaggtt
4861 tctagagtca ttttataccc aaggaataca tgtgtaatgt cctaaaacag aactgtcaat
4921 ttaaaaatat ttaatattat acctcctttc aaaagtttct aaaagctttg gagtttttag
4981 ttttataaat atgtgtccat aaaaattgtt ttctcactcc tgattctcta aatatgtcac
5041 aatccaaaac taagaaaagc actataaaaa caaatgaaag atggtattaa aaacactatt
5101 atttatatgt taagtttatg caagaggcaa tattttaaat cttctaagta aaccttatga
5161 atcatcttag tatgagagca gagaaaggaa aaaaggctca atgctcctct aatttttaac
5221 aatctaacaa tgtatattta ataaaaacta aatagaaatt attcatattt ttcatttaag
5281 catatttgtt ggcatgggag tcagatgact agatttttcc cacagtgact ttttcattct
5341 aggtggtgat gtttaaagac aatataaaca tgcagtttat tattactaat cagttagact
5401 actgttgctt cttaagtagt ccataggcct catagatcac tcatgaaaaa tgttttaaaa
5461 aataaaaaga aaacatattt tgtctttaac acaaaagatt tttttaactg atttaagtac
5521 tttttttttc ttttttaact tatttctcat tatttcttct tctggaactc cccaggctgt
5581 ggaggttcaa aaccagaaac aaccagcagt aagtctattt taattacttc tgttacaggc
5641 atgaactaca aaatatattc tgcaaaggtc aattgtatta tagatgcctt ctgtctaaaa
5701 cctaaatatt tcatttccat aaaacaatct aataatattt gcaagaaaat aatttcagca
5761 acaggtgata tgaatcaaca ttgatgttca tctgaaagtt ttattttctt atataaccca
5821 aatcatgtat ctttggtttt catgtatatt tagcaatatg agaaaactct ttcaacattt
5881 catattggaa aaaaatgaaa acataagtaa agcttaatat ttcccctttc cactttttaa
5941 gacaagggaa gatccttttc tgacccatct ttgaatactt ctcatacatc tatatttact
6001 tcccctttcg tttcccaaat atgtttgaat acatttaaat gtgtctcgtt ttaggagaaa
6061 tgtttgcttt gtagtataat tttgtcaatt tatttctatt catatggaaa ggtctactga
6121 caaattttta aacagaggca catagatata gacaattctt tatctaatct tttgtgaaga
6181 aaattaaacc aaaaaaaatc caaaatctaa atccaggaat ctctccacat cacattatgt
6241 tactattctg ctatagtttg gaaaaaataa atgtgctctt gggctaattt ttaaatgaat
6301 aaaatttgag accaattaca aatatgtggt gagaatacat acgtgtgtgt gcgccattct
6361 gtgtgtgtct gcatgttgtg cttgtgtata acatgtcaaa gttctcaatg agatttttct
6421 ctgtgttgta cctacaatag ctaacatata agatcacttt ccatatatgc caatctctgg
6481 gcaatatggt ttacattatg aataaactca tctaatttct tgaaacaaat attatattaa
6541 tattatcaaa ataatattta taatattgaa aatcataaag tggaaaggca atgtacaaat
6601 caacatctta taaaataata ttgctgctgg gttccatact tctaatatct tactcaatgg
6661 taaatactat attatttcaa aaaatgcaga tttaaggtat ttccacattt gggtctataa
6721 taataatatt ctgtataatt tatttttttt gcagtgccat gagaatgatg aaagaccatt
6781 ctatcagaaa acagctccat atgtcccaat gtattatgtg ccaaatagct atccttatta
6841 tggaaccaat ttgtaccaac gtagaccagc tatagcaatt aataatccat atgtgcctcg
6901 cacatattat gcaaacccag ctgtagttag gccacatgcc caaattcctc agcggcaata
6961 cctgccaaat agccacccac ccactgtggt acgtctccca aacctgcatc catcatttat
7021 tgccatcccc ccaaagaaaa ttcaggataa aataatcatc cctaccatca ataccattgc
7081 tactgttgaa cctacaccag ctcctgccac tgaaccaacg gtggacagtg tagtcactcc
7141 agaagctttt tcagagtcca tcatcacgag cacccctgag acaaccacag ttgcagttac
7201 tccacctacg gcataaaaac accaaggaaa tatcaaagaa cacaacgcag gtaaattaac
7261 agtatataaa atgagtaatt ccgacaagaa gcatggattt atgaatacaa ccataaattc
7321 taaaatagta caaatagata aactaagtgt gttacagaag cagacaaaac agggtactta
7381 cagttttacc ttggtaaacc catagcattg atacaccaga ttctgttcca actagaaatt
7441 taaaataatt ttatttgaca aagtgaaaat aattggcaac ttcattatca aacttttttc
7501 tgacaattgg gacactctta gaatgtaata gttttatttc atccttattc acacacaaac
7561 tatgacagta gagtaaaaca gcaagtaaca ttttcatgat atttcaaaaa taatttttag
7621 aagaagttat atagaatatg agtttgagta aattttaatt ctgtaacaat tctcttgcac
7681 tctcattgta gtatgaacag agtaaaagga aatgatatgc ttccatgcat ttctttattt
7741 cagacatcat ttccaaaatg attcatgaag ttaagcctct caaatttctc ctattctaag
7801 ataaacccat ggaagaatta taatgcttaa cttgaaaaac acataaatat taaaaggata
7861 ctttcagaac acaatgtgat gcaaagtgtt actatttatt acttggacca atggataatg
7921 gcagaatata aaataatttg aaacttatga gaagaattta aacaaagaga atgattaata
7981 aagtggaaaa tatccaaaga gtgtaaaata atttggggag aaagttgcaa aatgtggagt
8041 ttctttacaa caaatatttt cagtccatca gatgtctaca tgttttatga tctaaaatac
8101 cagacaatgg tctgtgatat catgggacta ccattagccc agaaaaggtt gcttctttca
8161 tctgcttgcc taatgaccat aggctagtca ttactttctc tgaactttta ttttctcata
8221 attctggttg ctataagact caagagagaa tgcacatggg aaaggatttt aaaaactgat
8281 caatctgtaa aatgtcatgt attggaaaag ataaagtaaa attcatacca gtatcctaag
8341 tctccactaa atgataaaaa ccgtacataa ttatgtctgt tgattcccat agtaaccata
8401 tgaaacagat attattccta tctcaaattt agggataaaa accagtagga ctgaggacat
8461 taagtaaatt atcacagcta gaaattgcaa atgggaggca aaccaaacct gtttatttca
8521 gatagtgggg tttaattact atgtcattta tttttatatg ggctgtctaa cttgctgaaa
8581 aacagggaaa atacactgtg atttccttag actagcatat gggtaaattg tgttgtttag
8641 ttgctgttca acaggatatc cattaagaaa aagagaacaa gagctggtta aacagctggc
8701 ttattatatt ttggagaaca aaataagaaa attaataaag acaacatgaa agcaagttat
8761 ttaataagta gttacatatt ttactgatgc aaaacataaa gaagcatgta aaagagtttt
8821 ttctgtaaat attacataat gtctattatt ttcagtttac tatatgccta ttttaaatat
8881 ttaagtttaa atatgtaatc tgattgactt attggataca gacatgaaag aaaaattgtg
8941 gaagctaaat aaatatatat catgagaact gttaacatac tatgaataaa tttctaaact
9001 atcattattt tttataggac ttgctgaaac caaattacta cttcacactc tccttcagcc
9061 atttgtctgc cttcagtcaa cagaaaatgt gattttcaca gattcagctc ttctctcctt
9121 acattttaca ttcatgccac attcaatatt ttgattcttg cacaataaag ccaactgatt
9181 gcaactgatt ctttgagagg agtttgcaaa ggtacctcag ggatctctga aactttgaaa
9241 cgctatgaca aatttagtgt gagttagagt acacaaattt acctaaaggc agtgctcata
9301 gtttcatcag gttctcaaag tggttcatgg tctgacacta agaatttctc ctctaggatg
9361 acactgggac cagagaaaag ccaagccata gtgttccaat ccaggggacc acagagtgac
9421 tcttgagagc catgggaact ctagattatt cctgagagca aattctgggc acaggcaaac
9481 tacaaatgtc cagaactaca aacacagata cgttgcaaaa ttatagatgt tgacagagac
9541 tctaaacatg catgaccaga tttccccaca ctggactcca cagtctcaca tctgttcaaa
9601 cacacacaca cccccacacc acccacccac ccacacacac acacacacat cacacaccag
9661 aaagcttctg gaattcaggt attccagttt ggaaaaactc gtgaatattc aaggtccaag
9721 gataggacat agttgttttc ttaaacaaat attgcaagga aaatcaggtc acctttgtgc
9781 ttggtccata tttaacacat catgccagaa aaaataaaat tcactcagcc cttacaaaat
9841 gttt
//