LOCUS HSU50939 1823 bp mRNA linear HUM 16-MAY-1996
DEFINITION Human amyloid precursor protein-binding protein 1 mRNA, complete
cds.
ACCESSION U50939
VERSION U50939.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1823)
AUTHORS Chow,N., Korenberg,J.R., Chen,X.N. and Neve,R.L.
TITLE APP-BP1, a novel protein that binds to the carboxyl-terminal region
of the amyloid precursor protein
JOURNAL J. Biol. Chem. 271 (19), 11339-11346 (1996)
PUBMED 8626687
REFERENCE 2 (bases 1 to 1823)
AUTHORS Chow,N.
TITLE Direct Submission
JOURNAL Submitted (08-MAR-1996) Nienwen Chow, Neurobiology & Anatomy, Univ.
Rochester, 601 Elmwood Ave., Rochester, NY 14642, USA
FEATURES Location/Qualifiers
source 1..1823
/db_xref="H-InvDB:HIT000220189"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16q22"
CDS 74..1678
/function="binds to the carboxyl-terminal region of the
amyloid precursor protein"
/experiment="experimental evidence, no additional details
recorded"
/note="APP-BP1"
/codon_start=1
/product="amyloid precursor protein-binding protein 1"
/protein_id="AAC50477.1"
/translation="MAQLGKLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTE
ILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSG
SFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVG
YMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVII
AKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTAL
NTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTIPDMIA
DSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAFLRV
VRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQV
EEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKI
ITKQFVIFNNTYIYSGMSQTSATFQL"
BASE COUNT 587 a 320 c 404 g 512 t
ORIGIN
1 gaattccgcg cttgtggagc tggtggcggc gctccgcagg ggctcggctg ttttccgcgc
61 ggcaggcgcg gccatggcgc agctgggaaa gctgctcaag gagcagaagt acgaccggca
121 gctgaggttg tggggtgatc atgggcaaga ggctttagaa tctgctcatg tttgcctaat
181 aaatgcaaca gccacaggaa ctgaaattct taaaaacttg gtactaccag gtattggttc
241 gtttacaatt attgatggaa atcaggtcag cggagaagat gctggaaaca atttcttcct
301 tcaaagaagc agtatcggca agaaccgagc tgaagctgcc atggaattct tacaagaatt
361 aaatagcgat gtctctggaa gttttgtgga agagagtcca gaaaaccttc tagacaatga
421 tccctcattt ttctgtaggt ttactgttgt agttgcaact cagcttcctg aaagcacttc
481 actacgctta gcagatgtcc tctggaattc ccagattcct cttttgatct gtaggacata
541 tggactagtt ggttatatga ggatcattat aaaagaacat ccagtaatag aatctcatcc
601 agataatgca ttagaggatc tacgactaga taagccattt cctgaactga gagaacattt
661 tcagtcctat gatttggatc atatggaaaa aaaggaccac agtcatactc catggattgt
721 gatcatagct aaatatttag cacagtggta tagtgaaaca aatggacgaa tacctaaaac
781 gtataaagaa aaagaggact tcagagattt gattagacaa ggaattctaa aaaatgaaaa
841 tggggctcca gaagatgaag agaattttga agaagctatt aaaaatgtga acacagcact
901 aaatacaact cagatcccaa gcagtattga agatatattt aatgatgatc gctgcataaa
961 tatcaccaaa cagactccat cattttggat tttagctcgt gccttaaagg aatttgtggc
1021 caaagagggt caaggaaatt tacctgttcg aggcacaatt cctgatatga ttgcagattc
1081 aggcaaatat ataaaactgc aaaacgttta ccgtgaaaaa gcaaagaaag atgctgccgc
1141 tgtgggtaat catgttgcca aattgctgca gtccattggc caggcaccag agtccatttc
1201 agagaaagaa ttaaaattac tctgcagcaa ttctgcattt cttcgagtgg taagatgtcg
1261 atccttagct gaagaatatg gtttggatac aattaacaag gatgaaatta tttctagcat
1321 ggacaatcca gataatgaaa tagtgttgta cttaatgtta cgggctgttg atagatttca
1381 taaacaacag ggtagatatc caggagtatc taactatcaa gttgaagaag atataggaaa
1441 gttgaagtct tgtctcactg gcttccttca ggaatatggt ttatctgtaa tggtgaaaga
1501 tgattatgtc cacgaatttt gccgatatgg agctgctgag ccacatacca ttgctgcatt
1561 cttgggggga gctgctgctc aagaggtcat caaaataatc accaaacaat ttgtaatttt
1621 taataatact tacatttaca gtggcatgtc acaaacttca gcaactttcc agttgtagag
1681 taagcaagca ccttaagtag tgtgttaatg attgaaactg taattgcctt cgggttgtgc
1741 tttagtctgt aaaattctaa aggagagctg ctaaattgtt ttcttaataa acatttttct
1801 catttgtaaa aaaaaaggaa ttc
//