LOCUS HSU50203 1892 bp mRNA linear HUM 29-AUG-1996
DEFINITION Human aldehyde dehydrogenase E3' mRNA, partial cds.
ACCESSION U50203
VERSION U50203.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1892)
AUTHORS Kikonyogo,A. and Pietruszko,R.
TITLE Aldehyde dehydrogenase from adult human brain that dehydrogenates
gamma-aminobutyraldehyde: purification, characterization, cloning
and distribution
JOURNAL Biochem. J. 316 (Pt 1), 317-324 (1996)
PUBMED 8645224
REFERENCE 2 (bases 1 to 1892)
AUTHORS Pietruszko,R.
TITLE Direct Submission
JOURNAL Submitted (28-FEB-1996) Regina Pietruszko, Rutgers University,
Center of Alcohol Studies, Allison Road, Busch Campus, Piscataway,
NJ 08855, USA
FEATURES Location/Qualifiers
source 1..1892
/db_xref="H-InvDB:HIT000220138"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/sex="male"
/tissue_type="brain"
/dev_stage="adult"
CDS <1..1401
/EC_number="1.2.1.3"
/function="dehydrogenation of gamma-aminobutyraldehyde"
/experiment="experimental evidence, no additional details
recorded"
/citation=[1]
/codon_start=1
/product="aldehyde dehydrogenase E3'"
/protein_id="AAB06721.1"
/translation="EKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGME
RCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGE
HIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVS
ALLLAEIYSEAGVPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAK
GIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKF
TEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVP
EDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLA
AGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYS
QLKTVCVEMGDVESAF"
BASE COUNT 531 a 381 c 463 g 517 t
ORIGIN
1 gagaaagctt tcgagccagc aaccggccga gtgatagcta ctttcacatg ttcaggagaa
61 aaggaagtaa atttggctgt tcaaaatgca aaggctgctt ttaaaatatg gagtcaaaaa
121 tctggcatgg agcgttgccg aatccttttg gaggctgcca ggataataag ggaacgggag
181 gatgaaattg ctactatgga gtgcatcaac aatggcaagt ccatctttga ggcccgcttg
241 gacattgaca tttcctggca gtgcctggag tattatgcgg gcttggctgc atccatggct
301 ggtgaacaca tccagctccc aggtggatcg tttggttata ccagaagaga accacttggg
361 gtatgtgtgg gaataggagc atggaactac ccctttcaga ttgcctcttg gaagtcggct
421 ccagcattag cctgtggtaa tgccatggtc tttaaacctt ctccctttac acctgtttct
481 gcattgctac tggctgaaat ctacagtgag gctggtgtac ctcctgggct cttcaatgtg
541 gtgcagggag gggctgccac aggccagttt ctgtgtcagc atcccgatgt ggccaaagtc
601 tccttcactg gaagtgtgcc cactggcatg aagatcatgg agatgtcagc taaaggaatc
661 aaacctgtta ccttggaact tggaggcaaa tctccactca tcatcttctc agactgtgat
721 atgaacaatg ctgtaaaggg ggcgctgatg gccaacttcc tcacacaagg ccaggtttgc
781 tgtaatggca caagagtatt tgtgcagaaa gaaattcttg ataaatttac agaggaagtg
841 gtgaaacaga cccaaaggat taaaattgga gatccccttc tggaagatac aaggatgggt
901 ccactcatca accgaccaca cctggagcga gtccttgggt ttgtcaaagt ggcaaaggag
961 cagggtgcta aagtgttatg tggtggagat atatatgtac ctgaagatcc caaattaaag
1021 gatggatatt acatgagacc ttgtgtatta actaattgca gagacgacat gacctgtgtg
1081 aaggaagaga tctttgggcc tgttatgtcc attttatcat ttgacactga agctgaggtt
1141 ctagaaagag ccaatgatac cacttttgga ctagcagctg gcgtctttac cagggacatc
1201 caacgggctc atagagtggt agctgagctt caggctggga cgtgcttcat taacaactat
1261 aacgtcagcc cagtggagtt gccctttggt ggatataaga agtcaggatt tggcagagag
1321 aacggccgtg tgacaatcga atattattca cagctgaaga ctgtgtgtgt ggagatgggt
1381 gatgtggaat ctgctttttg aaaacctgca gtgaaaccta ttgacatggc acgctgtgga
1441 atgatgtgaa ttggccctgt ttacagaggc agtacaactg aatgttattt tacatccaga
1501 attttggcgt tcagtataag agaatggttc atgttactct ttctctctcc atcagcttcc
1561 tcactgaaaa tgtgcattaa gtgccttgta gatactaatc aagaaagctg tgattctcct
1621 caaagcgtat ttttgtgaaa tcttttaaga gccagtaaca tacttctaga gaacaggaaa
1681 agagactaga ataatacatc ttccacacat ttggcccact gataatgtta attctctggc
1741 gtatttcaaa gaacttgttc ctggctgatc caagtgcagt ggtatttaca actaattgat
1801 cacaaccagt ttgtagattt ctttgttcct tctccattcc cactgcttca cttgcctagt
1861 cttgaagaaa aaaaacaaaa aacaaaaaaa aa
//