LOCUS HSU49928 3096 bp mRNA linear HUM 06-APR-1998
DEFINITION Homo sapiens TAK1 binding protein (TAB1) mRNA, complete cds.
ACCESSION U49928
VERSION U49928.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3096)
AUTHORS Shibuya,H., Yamaguchi,K., Shirakabe,K., Tonegawa,A., Gotoh,Y.,
Ueno,N., Irie,K., Nishida,E. and Matsumoto,K.
TITLE TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal
transduction
JOURNAL Science 272 (5265), 1179-1182 (1996)
PUBMED 8638164
REFERENCE 2 (bases 1 to 3096)
AUTHORS Shibuya,H.
TITLE Direct Submission
JOURNAL Submitted (25-FEB-1996) Hiroshi Shibuya, Faculty of Pharmaceutical
Sciences, Hokkaido University, Nishi 6-chome, Kita 12, Kita-ku,
Sapporo, Hokkaido 060, Japan
FEATURES Location/Qualifiers
source 1..3096
/db_xref="H-InvDB:HIT000220125"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3096
/gene="TAB1"
CDS 21..1535
/gene="TAB1"
/note="activator for TAK1"
/codon_start=1
/product="TAK1 binding protein"
/protein_id="AAC12660.1"
/translation="MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGT
ESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADV
RRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLER
EISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRL
SQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQ
PLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRV
KRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSV
PYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTLDEATPTLTNQSPTLTLQSTNTHT
QSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVVTAP"
BASE COUNT 642 a 936 c 952 g 566 t
ORIGIN
1 gcccgcaggg ttcctccaag atggcggcgc agaggaggag cttgctgcag agtgagcagc
61 agccaagctg gacagatgac ctgcctctct gccacctctc tggggttggc tcagcctcca
121 accgcagcta ctctgctgat ggcaagggca ctgagagcca cccgccagag gacagctggc
181 tcaagttcag gagtgagaac aactgcttcc tgtatggggt cttcaacggc tatgatggca
241 accgagtgac caacttcgtg gcccagcggc tgtccgcaga gctcctgctg ggccagctga
301 atgccgagca cgccgaggcc gatgtgcggc gtgtgctgct gcaggccttc gatgtggtgg
361 agaggagctt cctggagtcc attgacgacg ccttggctga gaaggcaagc ctccagtcgc
421 aattgccaga gggagtccct cagcaccagc tgcctcctca gtatcagaag atccttgaga
481 gactcaagac gttagagagg gaaatttcgg gaggggccat ggccgttgtg gcggtccttc
541 tcaacaacaa gctctacgtc gccaatgtcg gtacaaaccg tgcactttta tgcaaatcga
601 cagtggatgg gttgcaggtg acacagctga acgtggacca caccacagag aacgaggatg
661 agctcttccg tctttcgcag ctgggcttgg atgctggaaa gatcaagcag gtggggatca
721 tctgtgggca ggagagcacc cggcggatcg gggattacaa ggttaaatat ggctacacgg
781 acattgacct tctcagcgct gccaagtcca aaccaatcat cgcagagcca gaaatccatg
841 gggcacagcc gctggatggg gtgacgggct tcttggtgct gatgtcggag gggttgtaca
901 aggccctaga ggcagcccat gggcctgggc aggccaacca ggagattgct gcgatgattg
961 acactgagtt tgccaagcag acctccctgg acgcagtggc ccaggccgtc gtggaccggg
1021 tgaagcgcat ccacagcgac accttcgcca gtggtgggga gcgtgccagg ttctgccccc
1081 ggcacgagga catgaccctg ctagtgagga actttggcta cccgctgggc gaaatgagcc
1141 agcccacacc gagcccagcc ccagctgcag gaggacgagt gtaccctgtg tctgtgccat
1201 actccagcgc ccagagcacc agcaagacca gcgtgaccct ctcccttgtc atgccctccc
1261 agggccagat ggtcaacggg gctcacagtg cttccaccct ggacgaagcc acccccaccc
1321 tcaccaacca aagcccgacc ttaaccctgc agtccaccaa cacgcacacg cagagcagca
1381 gctccagctc tgacggaggc ctcttccgct cccggcccgc ccactcgctc ccgcctggcg
1441 aggacggtcg tgttgagccc tatgtggact ttgctgagtt ttaccgcctc tggagcgtgg
1501 accatggcga gcagagcgtg gtgacagcac cgtagggcag ccggaggaat gcagcccaag
1561 cagggcctgg catggggcag gacagggtcc agccttttcc taacatctgc ctgtgccaca
1621 acggccagca ggtgccccat cctctgccca cagcagactc tgtcccatgg ctctccgggc
1681 agtagagtgt gtgagtgcag actggacctg tggttcatac cttgtcacca cccgggaagc
1741 tgaaggccac ttcctcccag atggcctcag ccaggaccat cgccctttct cagagcagag
1801 ggccaggtag ggaaaccgca gtgggcctgc aagccgcccg agcctcccca gcagcctcct
1861 acagagcagg aagaggcgcc ctgtgaaccc tgtagtgttg caggcccagc agaccctgct
1921 gtcccaagcc cacccctcct cccaccatca cctccctcac ctcgggacag tagccctcca
1981 cttctccagc ctctcagccc tgtgctcctg tatccagagt ggaacccagg ctggtgtccg
2041 tatctgtccc tgggccccac ccctggacct gccttggttg tgtcatctgt tgtaaacatt
2101 ccaggaggac caggggagca tctggggcct gggatggcca cagaaggggc aggccaggtg
2161 gaaaggagcc agggggaagt ggtctaagag acctggaact gccagaggat ggcggcctgg
2221 gcttccccag agccaggcgt gcgggagagg tgaggactgg ccccggtggg ctgaggcagg
2281 ggccgctgtc gtcaggcctg agccagggtg agctggtgcc tgccttgctt cttccttctg
2341 gtgctgtgaa gaccataggc tggcaggcag ctgagatgaa ctgtctttac cactgatgag
2401 gggcctctgc cggctgaggg tagcaagcag gggttgtgag tcaggctggg ggacttgttt
2461 gaaagaaaga ggagttggaa tgtggttccc aggagggaag aggttccttt gagacacagt
2521 aaccctggga ggcataggag aagggtcggg ccagcccagc ccagggcctg agttagacta
2581 tttcccacat gttctctgcc ttcagtgggg agggggtgcc accagggctg tcggccagga
2641 ttgccactcc tgtttcagag gaagcaggcc gagagacttg caccttggac aagccacaca
2701 atcagtgggg cagccagagc tcagacctga gccattgtgt cagtatccag gaccccccgg
2761 attctccacg ccctccccat ctcccagtct ccctgccccc catgccccag accggcccac
2821 cagggactag ccgctgtcgc acagcctctg gggtgcttgg tctctgcaaa gtcaaaggcc
2881 tgacagctct gtggcctggg aatccatttt cctgcgggag agcagggcct ggtgtggaac
2941 cagggagctg tgggaagcca cagcagaaat ggaagaaaaa caggtctcag cccagggtcc
3001 tcgctcactc cctcactccc cactttgaag ccatctctgt tctgcaggtg agaggattta
3061 aagtcagtca caaaggcttg ggaacaaaag gaattc
//