LOCUS HSU49240 3669 bp mRNA linear HUM 05-SEP-1996
DEFINITION Human symplekin mRNA, complete cds.
ACCESSION U49240
VERSION U49240.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3669)
AUTHORS Keon,B.H., Schafer,S., Kuhn,C., Grund,C. and Franke,W.W.
TITLE Symplekin, a novel type of tight junction plaque protein
JOURNAL J. Cell Biol. 134 (4), 1003-1018 (1996)
PUBMED 8769423
REFERENCE 2 (bases 1 to 3669)
AUTHORS Keon,B.H.
TITLE Direct Submission
JOURNAL Submitted (15-FEB-1996) Brigitte H. Keon, Cell Biology, German
Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg 69120,
Germany
FEATURES Location/Qualifiers
source 1..3669
/db_xref="H-InvDB:HIT000220084"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="colon carcinoma"
CDS 111..3539
/codon_start=1
/product="symplekin"
/protein_id="AAC50667.1"
/translation="MTQLYKVALQWMVKSRVISELQEACWDMVSAMAGDIILLLDSDN
DGIRTHAIKFVEGLIVTLSPRMADSEIPRRQEHDISLDRIPRDHPYIQYNVLWEEGKA
ALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKS
QVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDTRKRPR
DDSDSTLKKMKLEPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITAEFLQPLLTP
DNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGV
EQTKQCKEEPKEEKVVKTESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQAKRRPE
PIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAA
QVRIKILASLVTQFNSGLKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGASGSLD
KYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVVRKYCEDESRTYLGMST
LRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKRMYEKEQLREYVEKFALNY
LQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTE
AIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPE
LVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQH
GEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQL
MEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIMKQVWKYPKVWEGFIKCCQRTK
PQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEASGKQ
EPEAKEAPAGPLEEDDLEPLTLAPAPAPRPPQDLIGLRLAQEKALKRQLEEEQKLKPG
GVGAPSSSSPSPSPSARPGPPPSEEAMDFREEGPECETPGIFISMDDDSGLTEAALLD
SSLEGPLPKETAAGGLTLKEERSPQTLAPVGEDAMKTPSPAAEDAREPEAKGNS"
BASE COUNT 816 a 1135 c 1093 g 625 t
ORIGIN
1 ccgaggaggc atgcaagcga gacattgagt tgctgctgaa actcattgca aacctcaaca
61 tgctcttgag ggacgagaat gtgaacgtgg tgaagaaggc tatcctcacc atgacccagc
121 tctacaaggt ggccctgcag tggatggtaa agtcacgggt aattagcgag ctacaggagg
181 cctgctggga catggtatct gccatggcgg gggacatcat cctgctattg gactctgaca
241 atgacggcat ccgcacccac gccatcaagt ttgtggaggg cctcattgtc accctgtcac
301 cccgcatggc tgactcagag ataccccgac gccaggagca tgatatcagc ctggaccgca
361 tccctcgtga ccacccctac atccagtaca acgtgctatg ggaagagggc aaggcagcct
421 tggagcagct gcttaagttc atggtgcacc ctgccatctc ctccatcaac ctgaccacag
481 cgctgggctc ccttgccaat atcgcccgcc agagacccat gttcatgtct gaggtgatcc
541 aggcctatga aactctgcat gccaacctgc ccccgacgct ggccaaatcg caggtgagca
601 gtgtgcgtaa gaatctgaag ctgcacctgt tgagtgtgct gaagcacccg gcttccttgg
661 agttccaggc ccagatcacc accctgctgg tggacctggg cacacctcag gccgagatcg
721 cccgcaacat gccgagcagc aaggacaccc gcaagcggcc ccgcgatgac tcggactcca
781 cactcaagaa gatgaagctg gagcccaacc tgggggagga cgatgaggac aaagacttgg
841 agccaggccc gtcggggacc tcgaaggcct cagcgcagat ctccggccag tcagacacgg
901 acatcacagc tgagttcctg cagcctctgc tgacgcctga taatgtggct aatctggtcc
961 tcatcagcat ggtgtaccta cccgaggcca tgccagcctc cttccaggcc atctacaccc
1021 ccgtggagtc agcaggcacg gaagcccaga tcaagcacct ggctcggctc atggccacac
1081 agatgacagc tgccggactg ggaccaggtg tagagcagac caaacagtgc aaggaggagc
1141 ccaaggagga gaaggtggtg aagacagaga gcgtcctgat caagcggcgc ctgtcagccc
1201 agggccaagc catctcggtg gtgggttccc tgagctccat gtcccccctg gaggaagagg
1261 caccgcaggc caagaggagg ccagagccca ttatccctgt cactcagccc cggctggcag
1321 gcgctggtgg gcgcaagaaa attttccgtc tcagcgacgt gctgaagccc cttaccgatg
1381 cccaggtgga agccatgaag ctgggcgctg tgaagcggat cctgcgggct gagaaggctg
1441 tggcctgcag cggggcagcc caggtccgca taaagatcct ggccagcctg gtgacacagt
1501 tcaactcggg cctgaaggcg gaggtcctgt ccttcatcct ggaggatgtg cgggcccgcc
1561 tggacctggc cttcgcctgg ctctaccagg agtacaacgc ctacctggcc gcaggtgcct
1621 cgggctccct ggacaagtat gaggactgcc tcatccgcct gttgtctggc ctgcaggaga
1681 aaccagacca gaaggatggg atcttcacca aggttgtgct ggaggcgcca ctcatcacag
1741 agagtgccct ggaggtggtc cgcaagtact gcgaggatga gagtcgcacc tatctgggca
1801 tgtccacact tcgagacctg atcttcaagc gcccgtcccg ccagttccag tacctgcatg
1861 tcctcctcga cctcagctcc catgagaagg acaaggtgcg ctcccaggcc ctgctgttca
1921 tcaaacgcat gtatgagaag gagcagctgc gggagtatgt ggagaaattt gccctcaact
1981 acctgcagct cctggtgcac cccaacccac cgtctgtgct gtttggagct gacaaggaca
2041 cagaggtggc agcaccctgg acggaggaga cagtgaagca gtgtctgtac ctctacctgg
2101 ccctcctgcc tcagaaccac aagctgatcc acgaactggc ggccgtgtac actgaagcca
2161 tcgccgacat caagcggacg gtgctgaggg tcattgagca gccgatccga ggaatgggca
2221 tgaactcccc ggagctgctc ctgctggtgg aaaattgtcc caagggagca gagacactgg
2281 tcacgagatg tctgcacagc ctcacagaca aagtcccacc ctccccagag ctggtgaagc
2341 gggtccggga tctctaccac aagcgactgc cagacgtccg cttcctcatc ccggtgctca
2401 atgggctgga gaagaaagag gtgatccagg ccctgcctaa actcatcaaa ctcaacccca
2461 tcgtggtgaa ggaagtcttc aaccgcctgc tgggcaccca gcatggtgag ggaaactcag
2521 ccttgtcccc gctgaaccct ggagagctcc tgatcgcatt acacaacatt gactccgtga
2581 agtgcgacat gaaatccatc atcaaagcca ccaacctgtg ctttgcggag cggaacgtgt
2641 acacgtcaga ggtgctggcc gtggtgatgc agcagctgat ggagcagagc cccctgccca
2701 tgctgctcat gaggaccgtc atccagtccc tgaccatgta cccccgcctg gggggcttcg
2761 tcatgaacat cctgtcccgc ctcatcatga agcaggtgtg gaagtacccc aaggtgtggg
2821 agggcttcat caagtgctgc cagcgcacaa agccccagag cttccaggtc atcctgcagc
2881 tgccgcccca gcagctggga gccgtctttg acaagtgccc agagctccgg gagcccctgc
2941 tggcccatgt ccgctccttc accccccacc agcaagctca catccctaac tccatcatga
3001 ccatcttgga ggccagcggc aagcaggagc cagaggccaa ggaggcgcct gcggggccct
3061 tggaggagga tgatctggag cccctgacct tggccccggc cccagcaccc cggccccctc
3121 aggacctcat cggcctgcga ctggcccagg agaaggcctt aaagcggcag ctggaggagg
3181 aacagaagct gaagccggga ggagtgggag ccccctcctc ttcctccccc tctccctctc
3241 cgtcggcccg gccaggcccg cccccgtctg aggaagccat ggatttccgg gaggaggggc
3301 ctgagtgcga gaccccgggc atcttcatca gcatggatga cgactcgggg ctgaccgagg
3361 ccgcgctgtt ggactctagt ctcgagggcc ccctacccaa ggagacggca gcgggcgggc
3421 tgaccttgaa ggaggagcgg agcccccaga ccctcgcacc tgttggagaa gatgctatga
3481 agactcccag cccggctgcc gaggacgcca gggaacccga ggccaagggg aacagctgac
3541 ggggctcgag ggggaaaggg ggtgggacag ggactcgggg ctgggggacg gggcggggct
3601 tgacctgcgg gtgctttgcc ttaaaaagaa ataaaagatg tgaacttgga aaaaaaaaaa
3661 aaaaaaaag
//