LOCUS HSU49114 2771 bp mRNA linear HUM 08-MAR-1996
DEFINITION Human prohormone convertase 5 precursor (PC5) mRNA, partial cds.
ACCESSION U49114
VERSION U49114.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2771)
AUTHORS Reudelhuber,T.L.
TITLE Direct Submission
JOURNAL Submitted (13-FEB-1996) Timothy L. Reudelhuber, Clinical Research
Institute of Montreal, 110 Pine Avenue West, Montreal, Quebec H2W
1R7, Canada
FEATURES Location/Qualifiers
source 1..2771
/db_xref="H-InvDB:HIT000220080"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/dev_stage="adult"
gene 1..2771
/gene="PC5"
CDS <1..2700
/gene="PC5"
/codon_start=1
/product="prohormone convertase 5 precursor"
/protein_id="AAA91807.1"
/translation="LLCVLALLGGCLLPVCRTRVYTNHWAVKIAGGFPEANRIASKYG
FINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDY
DFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGI
ERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVG
IAFNAKIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQ
AFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYL
EECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFL
TWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPR
QHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNRHVNYLEHVVVAITITHPRRGDL
AIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLR
NFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSRVEDPTDDYGTEDYAGPCDP
ECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAPNCESC
FGSHGDQCMSCKYGYFLNEETNSCVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCT
ECRDGLSLQGSRCSVSCEDGRYFNGQDCQPCHRFCATCAGAGADGCINCTEGYFMEDG
RCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLDLGMCQMG
AICKDATEESWAEGGFCMLVKKNNLCQRKVLQQLCCKTCTFQG"
sig_peptide <1..54
/gene="PC5"
mat_peptide 301..2697
/gene="PC5"
/product="prohormone convertase 5"
misc_feature 55..300
/gene="PC5"
/note="propeptide"
regulatory 2753..2759
/regulatory_class="polyA_signal_sequence"
/gene="PC5"
BASE COUNT 751 a 692 c 728 g 600 t
ORIGIN
1 ctgctgtgcg tgctggcgct gctcgggggc tgcctgctcc ccgtgtgtcg gacgcgcgtc
61 tacaccaacc actgggcagt caaaatcgcc gggggcttcc cggaggccaa ccgtatcgcc
121 agcaagtacg gattcatcaa cataggacag ataggggccc tgaaggacta ctaccacttc
181 taccatagca ggacgattaa aaggtcagtt atctcgagca gagggaccca cagtttcatt
241 tcaatggaac caaaggtgga atggatccaa cagcaagtgg taaaaaagcg gacaaagagg
301 gattatgact tcagtcgtgc ccagtctacc tatttcaatg atcccaagtg gcccagcatg
361 tggtatatgc actgcagtga caatacacat ccctgccagt ctgacatgaa tatcgaagga
421 gcctggaaga gaggctacac gggaaagaac attgtggtca ctatcctgga tgacggaatt
481 gagagaaccc atccagatct gatgcaaaac tacgatgctc tggcaagttg cgacgtgaat
541 gggaatgact tggacccaat gcctcgttat gatgcaagca acgagaacaa gcatgggact
601 cgctgtgctg gagaagtggc agccgctgca aacaattcgc actgcacagt cggaattgct
661 ttcaacgcca agatcggagg agtgcgaatg ctggacggag atgtcacgga catggttgaa
721 gcaaaatcag ttagcttcaa cccccagcac gtgcacattt acagcgccag ctggggcccg
781 gatgatgatg gcaagactgt ggacggacca gcccccctca cccggcaagc ctttgaaaac
841 ggcgttagaa tggggcggag aggcctcggc tctgtgtttg tttgggcatc tggaaatggt
901 ggaaggagca aagaccactg ctcctgtgat ggctacacca acagcatcta caccatctcc
961 atcagcagca ctgcagaaag cggaaagaaa ccttggtacc tggaagagtg ttcatccacg
1021 ctggccacaa cctacagcag cggggagtcc tacgataaga aaatcatcac tacagatctg
1081 aggcagcgtt gcacggacaa ccacactggg acgtcagcct cagcccccat ggctgcaggc
1141 atcattgcgc tggccctgga agccaatccg tttctgacct ggagagacgt acagcatgtt
1201 attgtcagga cttcccgtgc gggacatttg aacgctaatg actggaaaac caatgctgct
1261 ggttttaagg tgagccatct ttatggattt ggactgatgg acgcagaagc catggtgatg
1321 gaggcagaga agtggaccac cgttccccgg cagcacgtgt gtgtggagag cacagaccga
1381 caaatcaaga caatccgccc taacagtgca gtgcgctcca tctacaaagc ttcaggctgc
1441 tcggataacc ccaaccgcca tgtcaactac ctggagcacg tcgttgtggc catcaccatc
1501 acccacccca ggagaggaga cctggccatc tacctgacct cgccctctgg aactaggtct
1561 cagcttttgg ccaacaggct atttgatcac tccatggaag gattcaaaaa ctgggagttc
1621 atgaccattc attgctgggg agaaagagct gctggtgact gggtccttga agtttatgat
1681 actccctctc agctaaggaa ctttaagact ccaggtaaat tgaaagaatg gtctttggtc
1741 ctctacggca cctccgtgca gccatattca ccaaccaatg aatttccgaa agtggaacgg
1801 ttccgctata gccgagttga agaccccaca gacgactatg gcacagagga ttatgcaggt
1861 ccctgcgacc ctgagtgcag tgaggttggc tgtgacgggc caggaccaga ccactgcaat
1921 gactgtttgc actactacta caagctgaaa aacaatacca ggatctgtgt ctccagctgc
1981 ccccctggcc actaccacgc cgacaagaag cgctgcagga agtgtgcccc caactgtgag
2041 tcctgctttg ggagccatgg tgaccaatgc atgtcctgca aatatggata ctttctgaat
2101 gaagaaacca acagctgtgt tactcactgc cctgatgggt catatcagga taccaagaaa
2161 aatctttgcc ggaaatgcag tgaaaactgc aagacatgta ctgaattcca taactgtaca
2221 gaatgtaggg atgggttaag cctgcaggga tcccggtgct ctgtctcctg tgaagatgga
2281 cggtatttca acggccagga ctgccagccc tgccaccgct tctgcgccac ttgtgctggg
2341 gcaggagctg atgggtgcat taactgcaca gagggctact tcatggagga tgggagatgc
2401 gtgcagagct gtagtatcag ctattacttt gaccactctt cagagaatgg atacaaatcc
2461 tgcaaaaaat gtgatatcag ttgtttgacg tgcaatggcc caggattcaa gaactgtaca
2521 agctgcccta gtgggtatct cttagactta ggaatgtgtc aaatgggagc catttgcaag
2581 gatgcaacgg aagagtcctg ggcggaagga ggcttctgta tgcttgtgaa aaagaacaat
2641 ctgtgccaac ggaaggttct tcaacaactt tgctgcaaaa catgtacatt tcaaggctga
2701 gcagccatct tagatttctt tgttcctgta gacttataga ttattccata ttattaaaaa
2761 gaaaaaaaaa a
//