LOCUS HSU48437 2354 bp mRNA linear HUM 03-JUN-2002
DEFINITION Homo sapiens amyloid precursor-like protein 1 (APLP1) mRNA,
complete cds.
ACCESSION U48437
VERSION U48437.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2354)
AUTHORS Paliga,K., Peraus,G., Kreger,S., Durrwang,U., Hesse,L.,
Multhaup,G., Masters,C.L., Beyreuther,K. and Weidemann,A.
TITLE Human amyloid precursor-like protein 1--cDNA cloning, ectopic
expression in COS-7 cells and identification of soluble forms in
the cerebrospinal fluid
JOURNAL Eur. J. Biochem. 250 (2), 354-363 (1997)
PUBMED 9428684
REFERENCE 2 (bases 1 to 2354)
AUTHORS Paliga,K., Weidemann,A., Durrwang,U., Kreger,S., Schlatter,A.,
Masters,C.L. and Beyreuther,K.T.
TITLE Direct Submission
JOURNAL Submitted (06-FEB-1996) Krzysztof Paliga, Center for Molecular
Biology Heidelberg, University of Heidelberg, Im Neuenheimer Feld
282, Heidelberg, 69121, Germany
REFERENCE 3 (bases 1 to 2354)
AUTHORS Paliga,K.
TITLE Direct Submission
JOURNAL Submitted (06-DEC-1996) Center for Molecular Biology Heidelberg,
University of Heidelberg, Im Neuenheimer Feld 282, Heidelberg,
69121, Germany
REMARK Nucleotide and protein sequence updated by submitter
COMMENT On Dec 6, 1996 this sequence version replaced gi:1206030.
FEATURES Location/Qualifiers
source 1..2354
/db_xref="H-InvDB:HIT000220060"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2354
/gene="APLP1"
CDS 42..1994
/gene="APLP1"
/codon_start=1
/product="amyloid precursor-like protein 1"
/protein_id="AAB96331.1"
/translation="MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGS
PGAPEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPEL
QIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLH
QERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDP
SGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSH
TLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAM
ADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAAL
EGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVH
THLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKG
GLQPPDSKDDTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQ
RDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLT
LEEQQLRELQRHGYENPTYRFLEERP"
BASE COUNT 481 a 747 c 702 g 424 t
ORIGIN
1 gggcgggagt gcaggggacg tgagggcgca agggccggga catggggccc gccagccccg
61 ctgctcgcgg tctaagtcgc cgcccgggcc agccgccgct gccgctgctg ctgccactat
121 tgctgctgct tctgcgcgcg cagcccgcca tcgggagcct ggccggtggg agccccggcg
181 cgcccgaggc cccggggtcg gcccaggtgg ctggactatg cgggcgccta acccttcacc
241 gggacctgcg caccggccgc tgggaaccag acccacagcg ctctcgacgc tgtctccggg
301 acccgcagcg cgtgctggag tactgcagac agatgtaccc ggagctgcag attgcacgtg
361 tggagcaggc tacgcaggcc atccccatgg agcgctggtg cgggggttcc cggagcggca
421 gctgcgccca cccccaccac caggttgtgc ccttccgctg cctgcctggt gaatttgtga
481 gtgaggccct gctggtgcct gaaggctgcc ggttcttgca ccaggagcgc atggaccaat
541 gtgagagttc aacccggagg catcaggagg cacaggaggc ctgcagctcc cagggcctca
601 tcctgcacgg ctcgggcatg ctcttaccct gtggctcgga tcggttccgt ggtgtggagt
661 atgtgtgctg tccccctcca gggacccccg acccatctgg gacagcagtt ggtgacccct
721 ccacccggtc ctggcccccg gggagcagag tagagggggc tgaggacgag gaagaggagg
781 aatccttccc acagccagta gatgattact tcgtggagcc tccgcaggct gaagaggaag
841 aggaaacggt cccaccccca agctcccata cacttgcagt ggtcggcaaa gtcactccca
901 ccccgaggcc cacagacggt gtggatattt actttggcat gcctggggaa atcagtgagc
961 acgaggggtt cctgagagcc aagatggacc tggaggagcg taggatgcgc cagattaatg
1021 aggtgatgcg tgaatgggcc atggcagaca accagtccaa gaacctgcct aaagccgaca
1081 gacaggccct gaatgagcac ttccagtcca ttctgcagac tctggaggag caggtgtctg
1141 gtgagcgaca acgcctggtg gaaacccacg ccacccgcgt catcgccctt atcaacgacc
1201 agcgccgggc tgccttggag ggcttcctgg cagccctgca ggcagatccg cctcaggcgg
1261 agcgtgtcct gttggccctg cggcgctacc tgcgtgcgga gcagaaggaa cagaggcaca
1321 cgctgcgcca ctaccagcat gtggccgccg tggatcccga gaaggcacag cagatgcgct
1381 tccaggtgca tacccacctt caagtgattg aggagagggt gaatcagagc ctgggcctgc
1441 ttgaccagaa cccccacctg gctcaggagc tgcggcccca aatccaggaa ctcctccact
1501 ctgaacacct gggtcccagt gaattggaag cccctgcccc tgggggcagc agcgaggaca
1561 agggtgggct gcagcctcca gattccaagg atgacacccc catgaccctt ccaaaagggt
1621 ccacagaaca agatgctgca tcccctgaga aagagaagat gaacccgctg gaacagtatg
1681 agcgaaaggt gaatgcgtct gttccaaggg gtttcccttt ccactcatcg gagattcaga
1741 gggatgagct ggcaccagct gggacagggg tgtcccgtga ggctgtatcg ggtctgctga
1801 tcatgggagc gggcggaggc tccctcatcg tcctctccat gctgctcctg cgcaggaaga
1861 agccctacgg ggctatcagc catggcgtgg tggaggtgga ccccatgctg accctggagg
1921 agcagcagct ccgcgaactg cagcggcacg gctatgagaa ccccacttac cgcttcctgg
1981 aggaacgacc ctgacccggc cctcttcacc cctagccgag cccagacctc ccctcttcct
2041 ggagccccag aaccccaact cccagcctag ggcagcaggg agtcttgaaa gtgatcattt
2101 cacacccttt tgtgagacgg ctggaaattc ttatttcccc tttccaattc caaaattcca
2161 tccctaagaa ttcccagata gtcccagcag cctccccacg tggcacctcc tcaccttaat
2221 tttttaagtt tatttatggc tctttaaggt gaccgccacc ttggtcctag tgtctattcc
2281 ctggaattca ccctctcatg tttccctact aacatcccaa taaagtcctc ttccctaaaa
2341 aaaaaaaaaa aaaa
//