LOCUS HSU46005 2720 bp mRNA linear HUM 28-FEB-1997
DEFINITION Human MDC15 mRNA, complete cds.
ACCESSION U46005
VERSION U46005.1
KEYWORDS metalloproteinase-like; disintegrin-like; RGD; vascular.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2720)
AUTHORS Herren,B., Raines,E.W. and Ross,R.
TITLE Expression of a disintegrin-like protein in cultured human vascular
cells and in vivo
JOURNAL FASEB J. 11 (2), 173-180 (1997)
PUBMED 9039960
REFERENCE 2 (bases 1 to 2720)
AUTHORS Herren,B., Raines,E.W. and Ross,R.
TITLE Direct Submission
JOURNAL Submitted (12-JAN-1996) Barbara Herren, Pathology, University of
Washington, HSB, J503, Box 357470, Seattle, WA 98195, USA
FEATURES Location/Qualifiers
source 1..2720
/db_xref="H-InvDB:HIT000219980"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="endothelial cells"
/tissue_type="umbilical vein"
CDS 1..2445
/note="metalloprotein-like, disintegrin-like protein"
/codon_start=1
/product="MDC15"
/protein_id="AAC51112.1"
/translation="MRLALLWALGLLGAGSPLPSWPLPNIGGTEEQQAESEKAPREPL
EPQVLQDDLPISLKKVLQTSLPEPLRIKLELDGDSHILELLQNRELVPGRPTLVWYQP
DGTRVVSEGHTLENCCYQGRVRGYAGSWVSICTCSGLRGLVVLTPERSYTLEQGPGDL
QGPPIISRIQDLHLPGHTCALSWRESVHTQTPPEHPLGQRHIRRRRDVVTETKTVELV
IVADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPLNVRVALVGLEAWTQRDLVEISPN
PAVTLENFLHWRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD
HSTSILGVASSIAHELGHSLGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLPGLNFSN
CSRRALEKALLDGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFLDDCVDPCCDS
LTCQLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGDCDLPEFCPGDSSQCPPDVSLGD
GEPCAGGQAVCMHGRCASYAQQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRNPSG
SYVSCTPRDAICGQLQCQTGRTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLGSDVA
QPLLTLPGTACGPGLVCIDHRCQRVDLLGAQECRSKCHGHGVCDSNRHCYCEEGWAPP
DCTTQLKATSSLTTGLLLSLLVLLVLVMLGASYWYRARLXQRLCQLKGPTCQYRAAQS
GPSERPGPPQRALLARGTKSQGPAKPPPPRKPLPADPQGRCPSGDLPGPGPGIPPLVV
PSRPAPPPPTVSSLYL"
BASE COUNT 509 a 856 c 820 g 534 t
ORIGIN
1 atgcggctgg cgctgctctg ggccctgggg ctcctgggcg cgggcagccc tctgccttcc
61 tggccgctcc caaatatagg tggcactgag gagcagcagg cagagtcaga gaaggccccg
121 agggagccct tggagcccca ggtccttcag gacgatctcc caattagcct caaaaaggtg
181 cttcagacca gtctgcctga gcccctgagg atcaagttgg agctggacgg tgacagtcat
241 atcctggagc tgctacagaa tagggagttg gtcccaggcc gcccaaccct ggtgtggtac
301 cagcccgatg gcactcgggt ggtcagtgag ggacacactt tggagaactg ctgctaccag
361 ggaagagtgc ggggatatgc aggctcctgg gtgtccatct gcacctgctc tgggctcaga
421 ggcttggtgg tcctgacccc agagagaagc tataccctgg agcaggggcc tggggacctt
481 cagggtcctc ccattatttc gcgaatccaa gatctccacc tgccaggcca cacctgtgcc
541 ctgagctggc gggaatctgt acacactcag acgccaccag agcaccccct gggacagcgc
601 cacattcgcc ggaggcggga tgtggtaaca gagaccaaga ctgtggagtt ggtgattgtg
661 gctgatcact cggaggccca gaaataccgg gacttccagc acctgctaaa ccgcacactg
721 gaagtggccc tcttgctgga cacattcttc cggcccctga atgtacgagt ggcactagtg
781 ggcctggagg cctggaccca gcgtgacctg gtggagatca gcccaaaccc agctgtcacc
841 ctcgaaaact tcctccactg gcgcagggca catttgctgc ctcgattgcc ccatgacagt
901 gcccagctgg tgactggtac ttcattctct gggcctacgg tgggcatggc cattcagaac
961 tccatctgtt ctcctgactt ctcaggaggt gtgaacatgg accactccac cagcatcctg
1021 ggagtcgcct cctccatagc ccatgagttg ggccacagcc tgggcctgga ccatgatttg
1081 cctgggaata gctgcccctg tccaggtcca gccccagcca agacctgcat catggaggcc
1141 tccacagact tcctaccagg cctgaacttc agcaactgca gccgacgggc cctggagaaa
1201 gccctcctgg atggaatggg cagctgcctc ttcgaacggc tgcctagcct accccctatg
1261 gctgctttct gcggaaatat gtttgtggag ccgggcgagc agtgtgactg tggcttcctg
1321 gatgactgcg tcgatccctg ctgtgattct ttgacctgcc agctgaggcc aggtgcacag
1381 tgtgcatctg acggaccctg ttgtcaaaat tgccagctgc gcccgtctgg ctggcagtgt
1441 cgtcctacca gaggggattg tgacttgcct gaattctgcc caggagacag ctcccagtgt
1501 ccccctgatg tcagcctagg ggatggcgag ccctgcgctg gcgggcaagc tgtgtgcatg
1561 cacgggcgtt gtgcctccta tgcccagcag tgccagtcac tttggggacc tggagcccag
1621 cccgctgcgc cactttgcct ccagaccgct aatactcggg gaaatgcttt tgggagctgt
1681 gggcgcaacc ccagtggcag ttatgtgtcc tgcaccccta gagatgccat ttgtgggcag
1741 ctccagtgcc agacaggtag gacccagcct ctgctgggct ccatccggga tctactctgg
1801 gagacaatag atgtgaatgg gactgagctg aactgcagct gggtgcacct ggacctgggc
1861 agtgatgtgg cccagcccct cctgactctg cctggcacag cctgtggccc tggcctggtg
1921 tgtatagacc atcgatgcca gcgtgtggat ctcctggggg cacaggaatg tcgaagcaaa
1981 tgccatggac atggggtctg tgacagcaac aggcactgct actgtgagga gggctgggca
2041 ccccctgact gcaccactca gctcaaagca accagctccc tgaccacagg gctgctcctc
2101 agcctcctgg tcttattggt cctggtgatg cttggtgcca gctactggta ccgtgcccgc
2161 ctgvaccagc gactctgcca gctcaaggga cccacctgcc agtacagggc agcccaatct
2221 ggtccctctg aacggccagg acctccgcag agggccctgc tggcacgagg cactaagtct
2281 caggggccag ccaagccccc acccccaagg aagccactgc ctgccgaccc ccagggccgg
2341 tgcccatcgg gtgacctgcc cggcccaggg cctggaatcc cgcccctagt ggtaccctcc
2401 agaccagcgc caccgcctcc gacagtgtcc tcgctctacc tctgacctct ccggaggttc
2461 cgctgcctcc aagccggact tagggcttca agaggcgggc gtgccctctg gagtccccta
2521 ccatgactga aggcgccaga gactggcggt gtcttaagac tccgggcacc gccacgcgct
2581 gtcaagcaac actctgcgga cctgccggcg tagttgcagc gggggcttgg ggaggggctg
2641 ggggttggac gggattgagg aaggtccgca cagcctgtct ctgctcagtt gcaataaacg
2701 tgacatcttg ggagcgttaa
//