LOCUS HSU45285 2655 bp mRNA linear HUM 25-APR-1996
DEFINITION Human specific 116-kDa vacuolar proton pump subunit (OC-116KDa)
mRNA, complete cds.
ACCESSION U45285
VERSION U45285.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2655)
AUTHORS Li,Y.P., Chen,W. and Stashenko,P.
TITLE Molecular cloning and characterization of a putative novel human
osteoclast-specific 116-kDa vacuolar proton pump subunit
JOURNAL Biochem. Biophys. Res. Commun. 218 (3), 813-821 (1996)
PUBMED 8579597
REFERENCE 2 (bases 1 to 2655)
AUTHORS Li,Y.-P., Chen,W. and Stashenko,P.
TITLE Direct Submission
JOURNAL Submitted (09-JAN-1996) Yi-Ping Li, Cytokine Biology, Forsyth
Dental Center, 140 Fenway, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..2655
/db_xref="H-InvDB:HIT000219966"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="osteoclastoma tumor"
gene 1..2655
/gene="OC-116KDa"
CDS 58..2547
/gene="OC-116KDa"
/note="novel membrane bound protein with at least six
transmembrane domains"
/codon_start=1
/product="specific 116-kDa vacuolar proton pump subunit"
/protein_id="AAA97878.1"
/translation="MGSMFRSEEVALVQLFLPTAAAYTCVSRLGELGLVEFRDLNASV
SAFQRRFVVDVWRCEELEKTFTFLQEEVRRAGLVLPPPKGRLPAPPPRDLLRIQEETE
RLAQELRDVRGNQQALRAQLHQLQLHAAVLRQGHEPQLAAAHTDGASERTPLLQAPGG
PHQDLRVNFVAGAVEPHKAPALERLLWRACRGFLIASFRELEQPLEHPVTGEPATWMT
FLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETER
FLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQE
ALRDSSMEEGVSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDRYGVGRYQEVNPAPYT
IITFPFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLM
GLFSIYTGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVF
LGPYPFGIDPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRL
LLETLPELTFLLGLFGYLVFLVIYKWLCVWAARAASPSILIHFINMFLFSHSPSNRLL
YPRQEVVQATLVVLALAMVPILLLGTPLHLLHRHRRRLRRRPADRQEENKAGLLDLPD
ASVNGWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALS
LAHAQLSEVLWAMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLH
ALRLHWVEFQNKFYSGTGYKLSPFTFAATDD"
BASE COUNT 460 a 885 c 824 g 486 t
ORIGIN
1 cggcgtgcgc ggacgggcag ccagcagcgg aggcgcggcg cagcacaccc ggggaccatg
61 ggctccatgt tccggagcga ggaggtggcc ctggtccagc tctttctgcc cacagcggct
121 gcctacacct gcgtgagtcg gctgggcgag ctgggcctcg tggagttcag agacctcaac
181 gcctcggtga gcgccttcca gagacgcttt gtggttgatg tttggcgctg tgaggagctg
241 gagaagacct tcaccttcct gcaggaggag gtgcggcggg ctgggctggt cctgcccccg
301 ccaaagggga ggctgccggc acccccaccc cgggacctgc tgcgcatcca ggaggagacg
361 gagcgcctgg cccaggagct gcgggatgtg cggggcaacc agcaggccct gcgggcccag
421 ctgcaccagc tgcagctcca cgccgccgtg ctacgccagg gccatgaacc tcagctggca
481 gccgcccaca cagatggggc ctcagagagg acgcccctgc tccaggcccc cggggggccg
541 caccaggacc tgagggtcaa ctttgtggca ggtgccgtgg agccccacaa ggcccctgcc
601 ctagagcgcc tgctctggag ggcctgccgc ggcttcctca ttgccagctt cagggagctg
661 gagcagccgc tggagcaccc cgtgacgggc gagccagcca cgtggatgac cttcctcatc
721 tcctactggg gtgagcagat cggacagaag atccgcaaga tcacggactg cttccactgc
781 cacgtcttcc cgtttctgca gcaggaggag gcccgcctcg gggccctgca gcagctgcaa
841 cagcagagcc aggagctgca ggaggtcctc ggggagacag agcggttcct gagccaggtg
901 ctaggccggg tgctgcagct gctgccgcca gggcaggtgc aggtccacaa gatgaaggcc
961 gtgtacctgg ccctgaacca gtgcagcgtg agcaccacgc acaagtgcct cattgccgag
1021 gcctggtgct ctgtgcgaga cctgcccgcc ctgcaggagg ccctgcggga cagctcgatg
1081 gaggagggag tgagtgccgt ggctcaccgc atcccctgcc gggacatgcc ccccacactc
1141 atccgcacca accgcttcac ggccagcttc cagggcatcg tggatcgcta cggcgtgggc
1201 cgctaccagg aggtcaaccc cgctccctac accatcatca ccttcccctt cctgtttgct
1261 gtgatgttcg gggatgtggg ccacgggctg ctcatgttcc tcttcgccct ggccatggtc
1321 cttgcggaga accgaccggc tgtgaaagcc gcgcagaacg agatctggca gactttcttc
1381 aggggccgct acctgctcct gcttatgggc ctgttctcca tctacaccgg cttcatctac
1441 aacgagtgct tcagtcgcgc caccagcatc ttcccctcgg gctggagtgt ggccgccatg
1501 gccaaccagt ctggctggag tgatgcattc ctggcccagc acacgatgct taccctggat
1561 cccaacgtca ccggtgtctt cctgggaccc tacccctttg gcatcgatcc tatttggagc
1621 ctggctgcca accacttgag cttcctcaac tccttcaaga tgaagatgtc cgtcatcctg
1681 ggcgtcgtgc acatggcctt tggggtggtc ctcggagtct tcaaccacgt gcactttggc
1741 cagaggcacc ggctgctgct ggagacgctg ccggagctca ccttcctgct gggactcttc
1801 ggttacctcg tgttcctagt catctacaag tggctgtgtg tctgggctgc cagggccgcc
1861 tcgcccagca tcctcatcca cttcatcaac atgttcctct tctcccacag ccccagcaac
1921 aggctgctct acccccggca ggaggtggtc caggccacgc tggtggtcct ggccttggcc
1981 atggtgccca tcctgctgct tggcacaccc ctgcacctgc tgcaccgcca ccgccgccgc
2041 ctgcggagga ggcccgctga ccgacaggag gaaaacaagg ccgggttgct ggacctgcct
2101 gacgcatctg tgaatggctg gagctccgat gaggaaaagg cagggggcct ggatgatgaa
2161 gaggaggccg agctcgtccc ctccgaggtg ctcatgcacc aggccatcca caccatcgag
2221 ttctgcctgg gctgcgtctc caacaccgcc tcctacctgc gcctgtgggc cctgagcctg
2281 gcccacgccc agctgtccga ggttctgtgg gccatggtga tgcgcatagg cctgggcctg
2341 ggccgggagg tgggcgtggc ggctgtggtg ctggtcccca tctttgccgc ctttgccgtg
2401 atgaccgtgg ctatcctgct ggtgatggag ggactctcag ccttcctgca cgccctgcgg
2461 ctgcactggg tggaattcca gaacaagttc tactcaggca cgggctacaa gctgagtccc
2521 ttcaccttcg ctgccacaga tgactagggc ccactgcagg tcctgccaga cctccttcct
2581 gacctctgag gcaggagagg aataaagacg gtccgccctg gcaaaaaaaa aaaaaaaaaa
2641 aaaaaaaaaa aaaaa
//