LOCUS HSU44772 2279 bp mRNA linear HUM 17-AUG-1996
DEFINITION Human palmitoyl protein thioesterase mRNA, complete cds.
ACCESSION U44772
VERSION U44772.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2279)
AUTHORS Vesa,J., Hellsten,E., Verkruyse,L.A., Camp,L.A., Rapola,J.,
Santavuori,P., Hofmann,S.L. and Peltonen,L.
TITLE Mutations in the palmitoyl protein thioesterase gene causing
infantile neuronal ceroid lipofuscinosis
JOURNAL Nature 376 (6541), 584-587 (1995)
PUBMED 7637805
REFERENCE 2 (bases 1 to 2279)
AUTHORS Crews,C.M., Lane,W.S. and Schreiber,S.L.
TITLE Didemnin binds to the protein palmitoyl thioesterase responsible
for infantile neuronal ceroid lipofuscinosis
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 93 (9), 4316-4319 (1996)
PUBMED 8633062
REFERENCE 3 (bases 1 to 2279)
AUTHORS Crews,C.M.
TITLE Direct Submission
JOURNAL Submitted (04-JAN-1996) Craig M. Crews, Biology, Yale University,
219 Prospect Street, New Haven, CT 06520-8103, USA
FEATURES Location/Qualifiers
source 1..2279
/db_xref="H-InvDB:HIT000219952"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Jurkatt T cell line"
CDS 14..934
/codon_start=1
/product="palmitoyl protein thioesterase"
/protein_id="AAB06236.1"
/translation="MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDS
CCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKD
PKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHIC
DFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKN
LMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDN
AGQLVFLATEGDHLQLSEEWFYAHIIPFLG"
BASE COUNT 625 a 509 c 518 g 627 t
ORIGIN
1 ggcacgagcg aagatggcgt cgcccggctg cctgtggctc ttggctgtgg ctctcctgcc
61 atggacctgc gcttctcggg cgctgcagca tctggacccg ccggcgccgc tgccgttggt
121 gatctggcat gggatgggag acagctgttg caatccctta agcatgggtg ctattaaaaa
181 aatggtggag aagaaaatac ctggaattta cgtcttatct ttagagattg ggaagaccct
241 gatggaggac gtggagaaca gcttcttctt gaatgtcaat tcccaagtaa caacagtgtg
301 tcaggcactt gctaaggatc ctaaattgca gcaaggctac aatgctatgg gattctccca
361 gggaggccaa tttctgaggg cagtggctca gagatgccct tcacctccca tgatcaatct
421 gatctcggtt gggggacaac atcaaggtgt ttttggactc cctcgatgcc caggagagag
481 ctctcacatc tgtgacttca tccgaaaaac actgaatgct ggggcgtact ccaaagttgt
541 tcaggaacgc ctcgtgcaag ccgaatactg gcatgacccc ataaaggagg atgtgtatcg
601 caaccacagc atcttcttgg cagatataaa tcaggagcgg ggtatcaatg agtcctacaa
661 gaaaaacctg atggccctga agaagtttgt gatggtgaaa ttcctcaatg attccattgt
721 ggaccctgta gattcggagt ggtttggatt ttacagaagt ggccaagcca aggaaaccat
781 tcccttacag gagacctccc tgtacacaca ggaccgcctg gggctaaagg aaatggacaa
841 tgcaggacag ctagtgtttc tggctacaga aggggaccat cttcagttgt ctgaagaatg
901 gttttatgcc cacatcatac cattccttgg atgaaacccg tatagttcac aatagagctc
961 agggagcccc taactcttcc aaaccacatg ggagacagtt tccttcatgc ccaagcctga
1021 gctcagatcc agcttgcaac taatccttct atcatctaac atgcactact tggaaagatc
1081 taagatctga atcttatcct ttgccatctt ctgttaccat atggtgttga atgcaagttt
1141 aattaccatg gagattgttt tacaaacttt tgatgtggtc aagttcagtt ttagaaaagg
1201 gagtctgttc cagatcaggg ccagaactgt gcccaggccc aaaggagaca actaactaaa
1261 gtagtgagat agattctaag ggcaaacatt tttccaagtc ttgccatatt tcaagcaaag
1321 aggtgcccag gcctgaggta ctcacataaa tgctttgttt tgctggtgat ttaaccagtg
1381 cttggaaaaa tcttgcttgg ctatttctgc atcatttctt aaggctgcct tcctctctga
1441 gtacgttgcc ctctgtgcta tcaatcatct tatcatcaat tattagacaa atcccactgg
1501 cctacagtct tgcttctgca gcacccactt tgtctcctca ggtagtgatg aattagttgc
1561 tgtcacaaaa ggagggaagt agcacccaaa ttaaattgct taagagagga aatgtacatc
1621 ttgtataact tagggagcga agaaaatgta ggcgcgaaag tgaaaagtga ggcagctagt
1681 tcttcctatt ccattctcga ccaacctgcc ctttcttaat atgactagtg gtcttgatgc
1741 tagagtcaac ttactctgtt gctggcttta gcagagaata ggaggaacca tatgaaaaag
1801 atcaggcttt ctgacttcca tccccaaaac acatttacca gcatactcca aactgtttct
1861 gatgtgttcc atgagaaaag gattgtttgc tcaaaaagct tggaaaatac tacacactcc
1921 ctttctcctt ctggagatca acccacatta gagtgtctaa ggactcctga gaattcctgt
1981 tacagtaaac aaaactaacg taatctacca tttcctacac tatttgagca tggaaatcat
2041 agtccccact ctatgaaaac ttaacgcttt ttggaagaca tttctgtagc atgtcagttt
2101 ggagaaatga tgagctacgc cttgatgaaa gaaccgtgtt ggtgctgcta agtttagcca
2161 ttatggtttt tcctttctct ctcttaagcc ttattcttca actaaaagat gaggattaag
2221 agcaagaagt tgggggggat gtgaaaataa ttttatgagg ttgtctaaaa tctcgtgcc
//