LOCUS HSU43628 1598 bp mRNA linear HUM 12-JUN-1996
DEFINITION Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) mRNA,
complete cds.
ACCESSION U43628
VERSION U43628.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1598)
AUTHORS Shyjan,A.M., Bertagnolli,M., Kenney,C.J. and Briskin,M.J.
TITLE Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1)
demonstrates structural and functional similarities to the alpha 4
beta 7-integrin binding domains of murine MAdCAM-1, but extreme
divergence of mucin-like sequences
JOURNAL J. Immunol. 156 (8), 2851-2857 (1996)
PUBMED 8609404
REFERENCE 2 (bases 1 to 1598)
AUTHORS Briskin,M.J.
TITLE Direct Submission
JOURNAL Submitted (19-DEC-1995) Michael J. Briskin, Molecular Biology,
LeukoSite Inc., 215 First St., Cambridge, MA 02142, USA
FEATURES Location/Qualifiers
source 1..1598
/db_xref="H-InvDB:HIT000219867"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="4"
/tissue_type="mesenteric lymph node"
/clone_lib="lambda ziplox"
gene 1..1598
/gene="MAdCAM-1"
CDS 1..1221
/gene="MAdCAM-1"
/codon_start=1
/product="mucosal addressin cell adhesion molecule-1"
/protein_id="AAB02194.1"
/translation="MDFGLALLLAGLLGLLLGQSLQVKPLQVEPPEPVVAVALGASRQ
LTCRLACADRGASVQWRGLDTSLGAVQSDTGRSVLTVRNASLSAAGTRVCVGSCGGRT
FQHTVQLLVYAFPDQLTVSPAALVPGDPEVACTAHKVTPVDPNALSFSLLVGGQELEG
AQALGPEVQEEEEEPQGDEDVLFRVTERWRLPPLGTPVPPALYCQATMRLPGLELSHR
QAIPVLHSPTSPEPPDTTSPEPPNTTSPESPDTTSPESPDTTSQEPPDTTSQEPPDTT
SQEPPDTTSPEPPDKTSPEPAPQQGSTHTPRSPGSTRTRRPEISQAGPTQGEVIPTGS
SKPAGDQLPAALWTSSAVLGLLLLALPTYHLWKRCRHLAEDDTHPPASLRLLPQVSAW
AGLRGTGQVGISPS"
BASE COUNT 269 a 610 c 454 g 265 t
ORIGIN
1 atggatttcg gactggccct cctgctggcg gggcttctgg ggctcctcct cggccagtcc
61 ctccaggtga agcccctgca ggtggagccc ccggagccgg tggtggccgt ggccttgggc
121 gcctcgcgcc agctcacctg ccgcctggcc tgcgcggacc gcggggcctc ggtgcagtgg
181 cggggcctgg acaccagcct gggcgcggtg cagtcggaca cgggccgcag cgtcctcacc
241 gtgcgcaacg cctcgctgtc ggcggccggg acccgcgtgt gcgtgggctc ctgcgggggc
301 cgcaccttcc agcacaccgt gcagctcctt gtgtacgcct tcccggacca gctgaccgtc
361 tccccagcag ccctggtgcc tggtgacccg gaggtggcct gtacggccca caaagtcacg
421 cccgtggacc ccaacgcgct ctccttctcc ctgctcgtcg ggggccagga actggagggg
481 gcgcaagccc tgggcccgga ggtgcaggag gaggaggagg agccccaggg ggacgaggac
541 gtgctgttca gggtgacaga gcgctggcgg ctgccgcccc tggggacccc tgtcccgccc
601 gccctctact gccaggccac gatgaggctg cctggcttgg agctcagcca ccgccaggcc
661 atccccgtcc tgcacagccc gacctccccg gagcctcccg acaccacctc cccggagcct
721 cccaacacca cctccccgga gtctcccgac accacctccc cggagtctcc cgacaccacc
781 tcccaggagc ctcccgacac cacctcccag gagcctcccg acaccacctc ccaggagcct
841 cccgacacca cctccccgga gcctcccgac aagacctccc cggagcccgc cccccagcag
901 ggctccacac acacccccag gagcccaggc tccaccagga ctcgccgccc tgagatctcc
961 caggctgggc ccacgcaggg agaagtgatc ccaacaggct cgtccaaacc tgcgggtgac
1021 cagctgcccg cggctctgtg gaccagcagt gcggtgctgg gactgctgct cctggccttg
1081 cccacgtatc acctctggaa acgctgccgg cacctggctg aggacgacac ccacccacca
1141 gcttctctga ggcttctgcc ccaggtgtcg gcctgggctg ggttaagggg gaccggccag
1201 gtcgggatca gcccctcctg agtggccagc ctttccccct gtgaaagcaa aatagcttgg
1261 accccttcaa gttgagaact ggtcagggca aacctgcctc ccattctact caaagtcatc
1321 cctctgctca cagagatgga tgcatgttct gattgcctct ttggagaagc tcatcagaaa
1381 ctcaaaagaa ggccactgtt tgtctcacct acccatgacc tgaagcccct ccctgagtgg
1441 tccccacctt tctggacgga accacgtact ttttacatac attgattcat gtctcacgtc
1501 tccctaaaaa tgcgtaagac caagctgtgc cctgaccacc ctgggcccct gtcgtcagga
1561 cctcctgagg ctttggcaaa taaacctcct aaaatgat
//