LOCUS HSU43586 2126 bp mRNA linear HUM 30-JAN-1996
DEFINITION Human kinase suppressor of ras-1 (KSR1) mRNA, partial cds.
ACCESSION U43586
VERSION U43586.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2126)
AUTHORS Therrien,M., Chang,H.C., Solomon,N.M., Karim,F.D., Wassarman,D.A.
and Rubin,G.M.
TITLE KSR, a novel protein kinase required for RAS signal transduction
JOURNAL Cell 83 (6), 879-888 (1995)
PUBMED 8521512
REFERENCE 2 (bases 1 to 2126)
AUTHORS Therrien,M.
TITLE Direct Submission
JOURNAL Submitted (19-DEC-1995) Marc Therrien, Molecular and Cell Biology,
University of California, Berkeley, Life Sciences Annex, Box 539,
Berkeley, CA 94720-3200, USA
FEATURES Location/Qualifiers
source 1..2126
/db_xref="H-InvDB:HIT000219865"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2126
/gene="KSR1"
CDS <1..1908
/gene="KSR1"
/standard_name="kinase suppressor of ras-1"
/note="protein kinase related to Raf protein kinases;
Method: conceptual translation supplied by author."
/codon_start=1
/protein_id="AAC50354.1"
/translation="EFRHTSALTQHTAHTQHTSAHTQHSFITPPTTPQLRRHTKLKPP
RTPPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGL
SVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLPLTRLR
RTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPA
PFPTSSNPSSATTPPNPSPGQRDSRFNFPAAYFIHHRQQFIFPDISAFAHAAPLPEAA
DGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQ
TSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKK
EVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIA
QEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLS
HDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASI
WQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLS
HPGHFWKSAEL"
BASE COUNT 492 a 674 c 564 g 396 t
ORIGIN
1 gaattccggc acacatcagc actcacacag cacacagcac acacacagca cacatcagcg
61 cacacacagc acagcttcat caccccgccc accacacccc agctgcgacg gcacaccaag
121 ctgaagccac cacggacgcc ccccccaccc agccgcaagg tcttccagct gctgcccagc
181 ttccccacac tcacccggag caagtcccat gagtctcagc tggggaaccg cattgatgac
241 gtctcctcga tgaggtttga tctctcgcat ggatccccac agatggtacg gagggatatc
301 gggctgtcgg tgacgcacag gttctccacc aagtcctggc tgtcgcaggt ctgccacgtg
361 tgccagaaga gcatgatatt tggagtgaag tgcaagcatt gcaggttgaa gtgtcacaac
421 aaatgtacca aagaagcccc tgcctgtaga atatccttcc tgccactaac tcggcttcgg
481 aggacagaat ctgtcccctc ggacatcaac aacccggtgg acagagcagc cgaaccccat
541 tttggaaccc tccccaaagc actgacaaag aaggagcacc ctccggccat gaatcacctg
601 gactccagca gcaacccttc ctccaccacc tcctccacac cctcctcacc ggcgcccttc
661 ccgacatcat ccaacccatc cagcgccacc acgcccccca acccctcacc tggccagcgg
721 gacagcaggt tcaacttccc agctgcctac ttcattcatc atagacagca gtttatcttt
781 ccagacattt cagcctttgc acacgcagcc ccgctccctg aagctgccga cggtacccgg
841 ctcgatgacc agccgaaagc agatgtgttg gaagctcacg aagcggaggc tgaggagcca
901 gaggctggca agtcagaggc agaagacgat gaggacgagg tggacgactt gccgagctct
961 cgccggccct ggcggggccc catctctcgc aaggccagcc agaccagcgt gtacctgcag
1021 gagtgggaca tccccttcga gcaggtagag ctgggcgagc ccatcgggca gggccgctgg
1081 ggccgggtgc accgcggccg ctggcatggc gaggtggcca ttcgcctgct ggagatggac
1141 ggccacaacc aggaccacct gaagctcttc aagaaagagg tgatgaacta ccggcagacg
1201 cggcatgaga acgtggtgct cttcatgggg gcctgcatga acccgcccca cctggccatt
1261 atcaccagct tctgcaaggg gcggacgttg cactcgtttg tgagggaccc caagacgtct
1321 ctggacatca acaagacgag gcaaatcgct caggagatca tcaagggcat gggatatctt
1381 catgccaagg gcatcgtaca caaagatctc aaatctaaga acgtcttcta tgacaacggc
1441 aaggtggtca tcacagactt cgggctgttt gggatctcag gcgtggtccg agagggacgg
1501 cgtgagaacc agctaaagct gtcccacgac tggctgtgct atctggcccc tgagattgta
1561 cgcgagatga cccccgggaa ggacgaggat cagctgccat tctccaaagc tgctgatgtc
1621 tatgcatttg ggactgtttg gtatgagctg caagcaagag actggccctt gaagaaccag
1681 gctgcagagg catccatctg gcagattgga agcggggaag gaatgaagcg tgtcctgact
1741 tctgtcagct tggggaagga agtcagtgag atcctgtcgg cctgctgggc tttcgacctg
1801 caggagagac ccagcttcag cctgctgatg gacatgctgg agaaacttcc caagctgaac
1861 cggcggctct cccaccctgg acacttctgg aagtcagctg agttgtaggc ctggctgcct
1921 tgcatgcacc aggggctttc ttcctcctaa tcaacaactc agcaccgtga cttctgctaa
1981 aatgcaaaat gagatgcggg cactaaccca ggggatgcca cctctgctgc tccagtcgtc
2041 tctctcgagg ctacttcttt tgctttgttt taaaaactgg ccctctgccc tctccacgtg
2101 gcctgcatat gcccaagccg gaattc
//