LOCUS HSU43408 2771 bp mRNA linear HUM 05-APR-1996
DEFINITION Human tyrosine kinase (Tnk1) mRNA, complete cds.
ACCESSION U43408
VERSION U43408.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2771)
AUTHORS Hoehn,G.T., Stokland,T., Amin,S., Ramirez,M., Hawkins,A.L.,
Griffin,C.A., Small,D. and Civin,C.I.
TITLE Tnk1: a novel intracellular tyrosine kinase gene isolated from
human umbilical cord blood CD34+/Lin-/CD38- stem/progenitor cells
JOURNAL Oncogene 12 (4), 903-913 (1996)
PUBMED 8632913
REFERENCE 2 (bases 1 to 2771)
AUTHORS Hoehn,G.T.
TITLE Direct Submission
JOURNAL Submitted (15-DEC-1995) Gerard T. Hoehn, Pediatric Oncology, Johns
Hopkins University School of Medicine, 600 North Wolfe Street,
Baltimore, MD 21117, USA
FEATURES Location/Qualifiers
source 1..2771
/db_xref="H-InvDB:HIT000219856"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="pTnk1"
/cell_line="K562"
/cell_type="CD34+/Lin-/CD38- blood cells"
/tissue_type="umbilical cord blood"
gene 1..2771
/gene="Tnk1"
CDS 117..2117
/gene="Tnk1"
/codon_start=1
/product="tyrosine kinase"
/protein_id="AAC50427.1"
/translation="MLPEAGSLWLLKLLRDIQLAQFYWPILEELNVTRPGHFDFVKPE
DLDGIGMGRPAQRRLSEALKSLRSGPKSKNWVYKILGGFAPEHKEPTLPTDSPRHLPE
PEGGLKCLIPEGAVCRGELLGSGCFGVVHRGLWTLPSGKSVPVAVKSLRVGPEGPMGT
ELGDFLREVSVMMNLEHPHVLRLHGLVLGQPLQMVMELAPLGSLHARLTAPAPTPPLL
VALLCLFLRQLAGAMAYLGARGLVHRDLATRNLQLASPRTIKVADFGLVRPLGGARGR
YVMGGPRPIPYTWCAPESLRHGAFSSASDVWMFGVTLWEMFSGGEEPWPGVPPYLILQ
RLEDRARLPRPPPSSRALYSLALRCWAPHPADRPSFSHLEGLLQEAGPSEACCVRDAT
EPGALRMETGDPITVIEGSSSFHSPDSTIWKDQNGRTFKVGSFPASAVTLTDAGGLPA
TRPVHRGTPARGDQHPGSIDGDRKKANLWDAPPARGQRRNMPLERMKGISRSLESVLS
LGPRPTGGGSSPPEIRQARAVPQGPPGLPPRPPLSSSSPQPSQPSRERLPWPERKPPH
NHPMGMPGARKAAALSGGLLSDPELQRKIMEMELSVHWVTHQECQTALGATGGDVASA
IRNLKVDQLFLLSSRSRADCWRILEHYQWDLSAASRYVLARP"
BASE COUNT 534 a 885 c 814 g 538 t
ORIGIN
1 gagtcgccgc ttccgccttg accaggtgga gctggagacc tggtctctct agggcctgcc
61 ctgagctcac catctgaagg agagtgccat catccttagg aactccttct ccagacatgc
121 ttcccgaggc tggctccctg tggctactga agctgctccg ggacatccag ttggcccagt
181 tttactggcc catcctagag gagcttaatg tcacccggcc agggcacttc gactttgtaa
241 agcctgagga cctggacggc attggcatgg gccggcctgc ccaacgcaga ctgtccgaag
301 ctctgaaaag cctacgttct gggcctaagt ctaagaactg ggtctacaag atccttggag
361 gttttgcccc tgagcacaag gagcccaccc tgcccacgga cagcccacgg cacctccctg
421 agccagaggg gggcctcaag tgtctgatcc cagagggtgc tgtttgcaga ggggagctgc
481 tgggttcagg ctgcttcggt gtggtgcacc gagggctgtg gacgctgccc agtggcaaga
541 gtgtcccagt ggctgtcaag tccctccggg taggtcccga aggcccgatg ggcacagaac
601 tgggggactt cctgcgagag gtatcggtca tgatgaactt ggagcaccca cacgtgctgc
661 gtctgcacgg ccttgtactg ggccagcctc tgcagatggt gatggagctg gcgccactgg
721 gctccctgca cgcgcgctta acggccccgg ccccgacacc cccgctgctc gtggccctgc
781 tctgcctctt cctgcggcag ctggcgggag ccatggcgta cctgggggcc cgcgggctgg
841 tgcaccgaga cctcgctacg cgcaacctac agctggcgtc gccgcgcacc atcaaggtgg
901 ctgacttcgg gctggtgcgg cctctgggcg gtgcccgggg ccgctacgtc atgggcgggc
961 cccgccctat cccctacacc tggtgtgccc cagagagcct gcgccacgga gccttctcgt
1021 ctgcctcgga cgtgtggatg tttggggtga cgctgtggga gatgttctcc gggggcgagg
1081 aaccctggcc cggggtccca ccgtacctca tcctgcagcg gctggaggac agagcccggc
1141 tgcctaggcc tcccccctcc tccagggccc tctactccct cgccttgcgc tgctgggccc
1201 cccaccctgc cgaccggcct agcttttccc acctggaggg gctgctgcaa gaggccgggc
1261 cttcggaagc atgttgtgtg agggatgcca cagaaccagg cgccctgagg atggagactg
1321 gtgaccccat cacagtcatc gagggcagct cctctttcca cagccccgac tccacaatct
1381 ggaaggacca gaatggtcgc accttcaaag tgggcagctt cccagcctcg gcagtgacgc
1441 tgacagatgc ggggggcttg ccagccaccc gtccagtcca cagaggcacc cctgcccggg
1501 gagatcaaca cccaggaagc atagatggag acagaaagaa ggcaaatctt tgggatgcgc
1561 ccccagcacg gggccagagg aggaacatgc ccctggagag gatgaaaggc atttccagga
1621 gtctggagtc agttctgtcc ctcggtcctc gtcccacagg gggtggttca agcccccctg
1681 aaattcgaca agccagagct gtgccccagg gacctccagg cctgcctcca cgcccacctt
1741 tatcctctag ctctcctcag cccagccagc cctctaggga gaggcttccc tggcccgaaa
1801 gaaaaccccc acacaatcac cccatgggaa tgcctggagc ccgtaaagcc gctgccctct
1861 ctggaggcct cttgtccgat cctgagttgc agaggaagat tatggaaatg gagctgagtg
1921 tgcattgggt cacccaccag gagtgccaga cagcactagg agccactggg ggagatgtgg
1981 cttctgccat ccggaacctc aaggtagatc agctcttcct cctgagtagc cggtccagag
2041 ctgactgctg gcgcatcctg gagcattacc agtgggacct ctcagctgcc agccgttatg
2101 tcctggccag gccctgagcc cagcttctgc gggcacagac accagcatga aaagcctagg
2161 tccctgaggg cctggccaca tgggaccaag tggaaccaga acaaggcccc gacaggggta
2221 gacgttccac ttgtggagat cccacctgcc gctaggcacg tggaggagga gcccagagtt
2281 gggcactggc aaatgtctcc tccctcccat gctccttggc ttctgaaggc tgaagcccct
2341 ttggctgggc caagaaggat ctagtctgcc cactacattc tcaaacaaga ggacttggag
2401 gaaaagagct actatacatc atatgcagag gaagcttcta cgcgctagag aggatcaagg
2461 ggccacactg gaccatgtga acagccatcc ggaactgcca tcagctacca cactggactc
2521 tgcagggcag ccatcctgga tgatggaagc caccatattg acctggggta taggcccaaa
2581 ctgccttcgt ttggtccagg gccatcgtgg gtgatgacga ttgctctctt gcactcatgg
2641 acatttgatg ctggtagtat ggattatgag atggactagc ccctgctcca gcccagttct
2701 cacattcccc tttgtttttt cccataccaa ctgcttctac cctcccctat tacatacatc
2761 tttcaatgtc c
//