LOCUS HSU43293 1502 bp mRNA linear HUM 09-AUG-1996
DEFINITION Human MDS1A (AML1/MDS1 fusion) mRNA, partial cds.
ACCESSION U43293
VERSION U43293.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1502)
AUTHORS Fears,S., Mathieu,C., Zeleznik-Le,N., Huang,S., Rowley,J.D. and
Nucifora,G.
TITLE Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as
well as in myeloid leukemia and produces a new member of the PR
domain family
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 93 (4), 1642-1647 (1996)
PUBMED 8643684
REFERENCE 2 (bases 1 to 1502)
AUTHORS Nucifora,G.
TITLE Direct Submission
JOURNAL Submitted (14-DEC-1995) Giuseppina Nucifora, Medicine, University
of Chicago, 5841 S. Maryland, MC2115, Chicago, IL 60637, USA
FEATURES Location/Qualifiers
source 1..1502
/db_xref="H-InvDB:HIT000219842"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3q26"
/tissue_type="kidney"
/note="from patients with a t(3;21) translocation"
gene 1..1502
/gene="AML1/MDS1"
CDS <1..>345
/gene="AML1/MDS1"
/note="from a fusion of AML1 and MDS1 genes"
/codon_start=3
/product="MDS1A"
/protein_id="AAB05840.1"
/translation="NECVYGNYPEIPLEEMPDADGVASTPSLNIQEPCSPATSSEAFT
PKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQRS
NLKDPSYGWEVR"
BASE COUNT 474 a 235 c 272 g 521 t
ORIGIN
1 ataatgagtg tgtatatggc aactaccctg aaataccttt ggaagaaatg ccagatgcag
61 atggagtagc cagcactccc tccctcaata ttcaagagcc atgctctcct gccacatcca
121 gtgaagcatt cactccaaag gagggttctc cttacaaagc ccccatctac atccctgatg
181 atatccccat tcctgctgag tttgaacttc gagagtcaaa tatgcctggg gcaggactag
241 gaatatggac caaaaggaag atcgaagtag gtgaaaagtt tgggccttat gtgggagagc
301 agaggtcaaa cctgaaagac cccagttatg gatgggaggt aagaatgtat tttgagttaa
361 cacatttata tattgcagct gtgtaaagaa gagattgttt aagcatccac aaaataagca
421 aattatattt gttacaatat gttttcaaca ggtttttaag aataaacttc ctttacaatc
481 tcacttctta atacaaacaa tgtattgatt aaaggtatag cgtgatagga gggaacccaa
541 cctaatatat ggccaaagaa ttgtactgat ttgaaaaaat actaaaggaa gaagatatga
601 ttttatagtt aacgtttgga aacattggct atgaccacgt gtagcatgtg gcattagcaa
661 acaagcataa tcatatgaca tgtttattgc attttatctt ttttggggtc ggggatgtgg
721 aggattggag gaaaacattt gttttctcta ttttgtgact atgagttaat ttggttttat
781 tttcattttg tgctatgttt ttctaatata ttttgcctct cttttgataa ccctgcttta
841 attatacatg cttccagaat gtcagcactg tactcatcac tgaattaggt tatggttctt
901 tatattcaaa tgatttaatg agtaatttgt gcatcaaaac agacgcacaa aatggttgtg
961 aaaattagtc actcgtttca gtcatatttt tcataaaatc catttggcaa catctaagaa
1021 ttagaagtta tagtctgatt aaagaatcta aattaaattt atttcaataa agacaggtaa
1081 ctatgttatt cttctgagtg taagttttat acagattcag tagatatata tatactttcc
1141 atttatttct gtaacttgaa aacttttgtg cttgaatcat tacatcataa tttctggaaa
1201 atcttgtttc tatctgaaaa acttgtagac agtttctgca ggggtaagat attttttaga
1261 gatgtgattg acctttggtt tcatagcatt tcagtagaca gaaatcagat aaactggatt
1321 tatttcggta tgtttcctta atattatgat cattaataga tatctggtta gcttttaaat
1381 agaaatgaat attcagtgcc ttcaggactt aatttcaact ttttgtcctc ttgctttata
1441 tgtatcctct tgtgaaatct gttcaaaatg ccataataaa agcaattctt gttcaaattc
1501 tg
//