LOCUS HSU43142 2015 bp mRNA linear HUM 09-JAN-1996
DEFINITION Human vascular endothelial growth factor related protein VRP mRNA,
complete cds.
ACCESSION U43142
VERSION U43142.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2015)
AUTHORS Lee,J., Gray,A., Yuan,J., Luoh,S.-M., Avraham,H. and Wood,W.I.
TITLE Vascular Endothelial Growth Factor Related Protein (VRP): A Ligand
and Specific Activator of the Tyrosine Kinase Receptor Flt4
JOURNAL Proc. Natl. Acad. Sci. U.S.A. (1996) In press
REFERENCE 2 (bases 1 to 2015)
AUTHORS Wood,W.I.
TITLE Direct Submission
JOURNAL Submitted (12-DEC-1995) William I. Wood, Molecular Biology,
Genentech, Inc., 460 Pt. San Bruno Blvd., S. San Francisco, CA
94080, USA
FEATURES Location/Qualifiers
source 1..2015
/db_xref="H-InvDB:HIT000219830"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="vh1.4"
/cell_line="human glioma cell line G61"
source 206..2012
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="vh1.6"
CDS 372..1631
/function="ligand and activator of the receptor tyrosine
kinase Flt4"
/note="name is abbreviated as VRP or vh1"
/codon_start=1
/product="vascular endothelial growth factor related
protein"
/protein_id="AAA85214.1"
/translation="MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPD
AGEATAYASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSR
TEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVY
RCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVTISFANHTSCRCMSKLDVY
RQVHSIIRRSLPATLPQCQAANKTCPTNYMWNNHICRCLAQEDFMFSSDAGDDSTDGF
HDICGPNKELDEETCQCVCRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREF
DENTCQCVCKRTCPRNQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQ
KACEPGFSYSEEVCRCVPSYWKRPQMS"
polyA_site 2015
BASE COUNT 525 a 532 c 499 g 459 t
ORIGIN
1 cgcggggtgt tctggtgtcc cccgccccgc ctctccaaaa agctacaccg acgcggaccg
61 cggcggcgtc ctccctcgcc ctcgcttcac ctcgcgggct ccgaatgcgg ggagctcgga
121 tgtccggttt cctgtgaggc ttttacctga cacccgccgc ctttccccgg cactggctgg
181 gagggcgccc tgcaaagttg ggaacgcgga gccccggacc cgctcccgcc gcctccggct
241 cgcccagggg gggtcgccgg gaggagcccg ggggagaggg accaggaggg gcccgcggcc
301 tcgcaggggc gcccgcgccc ccacccctgc ccccgccagc ggaccggtcc cccacccccg
361 gtccttccac catgcacttg ctgggcttct tctctgtggc gtgttctctg ctcgccgctg
421 cgctgctccc gggtcctcgc gaggcgcccg ccgccgccgc cgccttcgag tccggactcg
481 acctctcgga cgcggagccc gacgcgggcg aggccacggc ttatgcaagc aaagatctgg
541 aggagcagtt acggtctgtg tccagtgtag atgaactcat gactgtactc tacccagaat
601 attggaaaat gtacaagtgt cagctaagga aaggaggctg gcaacataac agagaacagg
661 ccaacctcaa ctcaaggaca gaagagacta taaaatttgc tgcagcacat tataatacag
721 agatcttgaa aagtattgat aatgagtgga gaaagactca atgcatgcca cgggaggtgt
781 gtatagatgt ggggaaggag tttggagtcg cgacaaacac cttctttaaa cctccatgtg
841 tgtccgtcta cagatgtggg ggttgctgca atagtgaggg gctgcagtgc atgaacacca
901 gcacgagcta cctcagcaag acgttatttg aaattacagt gcctctctct caaggcccca
961 aaccagtaac aatcagtttt gccaatcaca cttcctgccg atgcatgtct aaactggatg
1021 tttacagaca agttcattcc attattagac gttccctgcc agcaacacta ccacagtgtc
1081 aggcagcgaa caagacctgc cccaccaatt acatgtggaa taatcacatc tgcagatgcc
1141 tggctcagga agattttatg ttttcctcgg atgctggaga tgactcaaca gatggattcc
1201 atgacatctg tggaccaaac aaggagctgg atgaagagac ctgtcagtgt gtctgcagag
1261 cggggcttcg gcctgccagc tgtggacccc acaaagaact agacagaaac tcatgccagt
1321 gtgtctgtaa aaacaaactc ttccccagcc aatgtggggc caaccgagaa tttgatgaaa
1381 acacatgcca gtgtgtatgt aaaagaacct gccccagaaa tcaaccccta aatcctggaa
1441 aatgtgcctg tgaatgtaca gaaagtccac agaaatgctt gttaaaagga aagaagttcc
1501 accaccaaac atgcagctgt tacagacggc catgtacgaa ccgccagaag gcttgtgagc
1561 caggattttc atatagtgaa gaagtgtgtc gttgtgtccc ttcatattgg aaaagaccac
1621 aaatgagcta agattgtact gttttccagt tcatcgattt tctattatgg aaaactgtgt
1681 tgccacagta gaactgtctg tgaacagaga gacccttgtg ggtccatgct aacaaagaca
1741 aaagtctgtc tttcctgaac catgtggata actttacaga aatggactgg agctcatctg
1801 caaaaggcct cttgtaaaga ctggttttct gccaatgacc aaacagccaa gattttcctc
1861 ttgtgatttc tttaaaagaa tgactatata atttatttcc actaaaaata ttgtttctgc
1921 attcattttt atagcaacaa caattggtaa aactcactgt gatcaatatt tttatatcat
1981 gcaaaatatg tttaaaataa aatgaaaatt gtatt
//